LOCUS       XP_025719182            1297 aa            linear   MAM 09-MAY-2025
DEFINITION  collagen alpha-1(XVIII) chain isoform X9 [Callorhinus ursinus].
ACCESSION   XP_025719182
VERSION     XP_025719182.1
DBLINK      BioProject: PRJNA481736
DBSOURCE    REFSEQ: accession XM_025863397.2
KEYWORDS    RefSeq.
SOURCE      Callorhinus ursinus (northern fur seal)
  ORGANISM  Callorhinus ursinus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia;
            Pinnipedia; Otariidae; Callorhinus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_027397160) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_003265705.2-RS_2025_05
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 05/07/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Callorhinus ursinus"
                     /isolate="GAN/ISIS: 27379988/994484"
                     /db_xref="taxon:34884"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="blood"
                     /dev_stage="adult"
     Protein         1..1297
                     /product="collagen alpha-1(XVIII) chain isoform X9"
                     /calculated_mol_wt=131802
     Region          41..229
                     /region_name="LamG"
                     /note="Laminin G domain; Laminin G-like domains are
                     usually Ca++ mediated receptors that can have binding
                     sites for steroids, beta1 integrins, heparin, sulfatides,
                     fibulin-1, and alpha-dystroglycans. Proteins that contain
                     LamG domains serve a variety of...; cl22861"
                     /db_xref="CDD:473984"
     Region          <362..>546
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          <589..>790
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          990..1038
                     /region_name="Collagen_trimer"
                     /note="Collagen trimerization domain; pfam20010"
                     /db_xref="CDD:466257"
     Region          1121..1290
                     /region_name="Endostatin-like"
                     /note="Endostatin-like domain; the angiogenesis inhibitor
                     endostatin is a C-terminal fragment of collagen XV/XVIII,
                     a proteoglycan/collagen found in vessel walls and basement
                     membranes; this domain has a compact globular fold similar
                     to that of C-type lectins; cd00247"
                     /db_xref="CDD:238151"
     Site            order(1151,1160,1166,1175..1176,1179,1241..1242,1252)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:238151"
     CDS             1..1297
                     /gene="COL18A1"
                     /coded_by="XM_025863397.2:88..3981"
                     /db_xref="GeneID:112816720"
ORIGIN      
        1 maprwpwlrp rprslldvla pvvlllgvrv asaepeslgt evgllqllge ppppqvtqve
       61 dpdvgpafvf gldansgqva ryhfpspffr dfslhfhvrp atedagvlfa itdaaqavvs
      121 vgvrlsgvrd ghqhiqllyt epgatrthta asfrlpaftg qwtrfalsvd gatvalfvdc
      181 elfqrvplvr sprglelepg aglfvaqagg adpdkfqgvi aelrvrgdph vsplhcleed
      241 degggrvsgd fgsgleetre plreqsgpsp kpslpeappv tspplaagrd vedsrteeie
      301 eettvsslga rirpgleavt tgsvwspggg leegpavqsp hawpvpgpqg ppgplgppgk
      361 dgapgrdgep gdpgedgrpg dpgpqgfpgt pgdagpkgek gdpgvgprgp pgpqgppgpp
      421 gpsfrhdklt fidmegsgfg gdleslrgpr gfpgppgppg vpglpgepgr fgmnssdvpg
      481 paglpgvpgr dgapglpgtp gppgppgkeg gpgkmgqkgs pgevgapgpk gskgdpgpvg
      541 apgenglaga pgpagppgpp gppgppgpel aagfddmegs ggpfwstaqg asgsqgppgp
      601 pgikgdpgit gppgakgevg aegppgfpgl pgregsagaq gpkgekgtqg ekgdpgrdgv
      661 gqpglpgppg ppgpvvymse qdkvlggvpg pegrpgfagf pgpagpkgdl gskgqrglpg
      721 pkgekgepgp lfspdgsmla paqkgakgep gfrgppgpyg rpghkgeigf pgrpgrpgmn
      781 glkgekgepg hssigfgmrg ppgppgppgp pgppgtpiyd snafmesgrp gppglpglqg
      841 psglkgdkgd vgppgppgqf pfdllqlgte mkgekgdrgd tgqkgeqgap ggggffgssv
      901 pgppgppgyp gipgpkgesi rgqpgppgpq gppgighegr qgppgppgpp gppgppsfpg
      961 pyrqtisvpg ppgppgppgp pgtmgtssgv riwatyqtml dkvpevpegw lifvaereel
     1021 yvrvrnglrk vllgprtplp rgtdnevaal qppvgnpypr relthstarp wraddilasp
     1081 prlpdpqpyp gapqhgsylh fqparptggp thththqdyh pvlhlvalns pqpggmrgir
     1141 gadfqcfqqa ravglagtfr aflssrlqdl ysvvrradrt svpivnlrde vlfpswealf
     1201 sgsegrlkpg arifsfdgrd vlqhpawpqk svwhgsdpsg rrltdsycet wrteaaaatg
     1261 qassllagrl laqkatgchn tlivlciens fmtsfsk
//