GenomeNet

Database: RefSeq
Entry: XP_026526021
LinkDB: XP_026526021
Original site: XP_026526021 
LOCUS       XP_026526021             437 aa            linear   VRT 06-OCT-2018
DEFINITION  suppressor of cytokine signaling 4 [Notechis scutatus].
ACCESSION   XP_026526021
VERSION     XP_026526021.1
DBLINK      BioProject: PRJNA494227
DBSOURCE    REFSEQ: accession XM_026670236.1
KEYWORDS    RefSeq.
SOURCE      Notechis scutatus (mainland tiger snake)
  ORGANISM  Notechis scutatus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata;
            Toxicofera; Serpentes; Colubroidea; Elapidae; Hydrophiinae;
            Notechis.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_020716642.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Notechis scutatus Annotation Release
                                           100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.1
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Notechis scutatus"
                     /db_xref="taxon:8663"
                     /chromosome="Unknown"
     Protein         1..437
                     /product="suppressor of cytokine signaling 4"
                     /calculated_mol_wt=50084
     Region          61..111
                     /region_name="SOCS"
                     /note="Suppressor of cytokine signalling; pfam12610"
                     /db_xref="CDD:432667"
     Region          272..372
                     /region_name="SH2_SOCS4"
                     /note="Src homology 2 (SH2) domain found in suppressor of
                     cytokine signaling (SOCS) proteins; cd10385"
                     /db_xref="CDD:198248"
     Site            order(280,282)
                     /site_type="other"
                     /note="Elongin-C binding interface [polypeptide binding]"
                     /db_xref="CDD:198248"
     Site            order(290,308,310,318,331)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198248"
     Site            order(341,343,361)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198248"
     Region          381..436
                     /region_name="SOCS"
                     /note="SOCS (suppressors of cytokine signaling) box. The
                     SOCS box is found in the C-terminal region of CIS/SOCS
                     family proteins (in combination with a SH2 domain), ASBs
                     (ankyrin repeat-containing proteins with a SOCS box), SSBs
                     (SPRY domain-containing proteins...; cl02533"
                     /db_xref="CDD:470605"
     Site            order(382..387,393,400,406)
                     /site_type="active"
                     /note="elongin B/C interaction [active]"
                     /db_xref="CDD:239641"
     CDS             1..437
                     /gene="SOCS4"
                     /coded_by="XM_026670236.1:1008..2321"
                     /db_xref="GeneID:113413735"
ORIGIN      
        1 maenkerkpk nadvrpktsr srsadrkdgy vwsgkklswi kknenssnaa manasgiptl
       61 slrnqerkqs cssaemeleh vcghrflsrs fkqklqdamg qcfpikscst rhssrlspkr
      121 kihiselmld kcpfpprsel afrwhlikqh tapvrqkses wlsmgsskge rkdeelreie
      181 madepdsgvl qessgienas ypcdpqeesa lggkqlkssr eesdmdsdde vvtlctssrk
      241 rnkpqweied dllqlqmplr yhtqidyvhc lvpdllqinn npcywgvmdk yaaealldgk
      301 pegtfllrds aqedylfsvs frrysrslha rieqwnhnfs fdahdpcvfh spditglleh
      361 ykdpsscmff epllstplhr tfpfslqhlc rtvicnstty dginalpvpp svklylkeyh
      421 ykskvrvlrv dvpdqha
//
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