LOCUS       XP_029570057             393 aa            linear   VRT 28-JAN-2026
DEFINITION  suppressor of cytokine signaling 4-like [Salmo trutta].
ACCESSION   XP_029570057
VERSION     XP_029570057.1
DBLINK      BioProject: PRJNA550988
DBSOURCE    REFSEQ: accession XM_029714197.1
KEYWORDS    RefSeq.
SOURCE      Salmo trutta (river trout)
  ORGANISM  Salmo trutta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
            Salmoniformes; Salmonidae; Salmoninae; Salmo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_042981.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_901001165.2-RS_2026_01
            Annotation Pipeline         :: NCBI Eukaryotic Genome Annotation
                                           Pipeline (EGAP)
            Annotation Software Version :: 10.5
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 01/26/2026
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Salmo trutta"
                     /db_xref="taxon:8032"
                     /chromosome="25"
     Protein         1..393
                     /product="suppressor of cytokine signaling 4-like"
                     /calculated_mol_wt=44241
     Region          59..109
                     /region_name="SOCS"
                     /note="Suppressor of cytokine signalling; pfam12610"
                     /db_xref="CDD:432667"
     Region          244..344
                     /region_name="SH2"
                     /note="Src homology 2 (SH2) domain; cl15255"
                     /db_xref="CDD:472789"
     Site            order(262,280,301,303)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198248"
     Site            order(302,332)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198248"
     Region          353..>393
                     /region_name="SOCS"
                     /note="SOCS (suppressors of cytokine signaling) box. The
                     SOCS box is found in the C-terminal region of CIS/SOCS
                     family proteins (in combination with a SH2 domain), ASBs
                     (ankyrin repeat-containing proteins with a SOCS box), SSBs
                     (SPRY domain-containing proteins...; cl02533"
                     /db_xref="CDD:470605"
     Site            order(354..359,365,372,378)
                     /site_type="active"
                     /note="elongin B/C interaction [active]"
                     /db_xref="CDD:239641"
     CDS             1..393
                     /gene="LOC115162742"
                     /coded_by="XM_029714197.1:1..1182"
                     /db_xref="GeneID:115162742"
ORIGIN      
        1 msekksrssd icpkcgicsw sadsylwsck krsrssrndp glrgpegvgp meeqgarsts
       61 cpprrrerkc sctvmgkvdi dvpcrkalsr rslrqkfqda vgqcfplrtd hhqhhhhhhg
      121 cptgayrgaf svllwtkrpi hvtelmqdkc pfsskselah cwhlikkhat hpsaivglev
      181 aqaakaaqaa gkepvpsast sppstplswe giclsrplsl edwdlshphg raayggshtd
      241 nilvpdllqi nnspcywgvl drfqaeellg gqpegtfllr dsaqdkflfs vsfrrysrsl
      301 harieqngkr fsfdgrdpcm yrdpsvtgll rhysdpatcl ffepllsrpl artfpftlqh
      361 lcravicsct tyqgikilpl pyqlrdylrq yhy
//