GenomeNet

Database: RefSeq
Entry: XP_032487974
LinkDB: XP_032487974
Original site: XP_032487974 
LOCUS       XP_032487974            1089 aa            linear   MAM 27-FEB-2020
DEFINITION  platelet-derived growth factor receptor alpha isoform X2 [Phocoena
            sinus].
ACCESSION   XP_032487974
VERSION     XP_032487974.1
DBLINK      BioProject: PRJNA606521
DBSOURCE    REFSEQ: accession XM_032632083.1
KEYWORDS    RefSeq.
SOURCE      Phocoena sinus (vaquita)
  ORGANISM  Phocoena sinus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha;
            Cetacea; Odontoceti; Phocoenidae; Phocoena.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_045767.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Phocoena sinus Annotation Release
                                           100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.3
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1089
                     /organism="Phocoena sinus"
                     /isolate="mPhoSin1"
                     /db_xref="taxon:42100"
                     /chromosome="5"
                     /sex="female"
                     /tissue_type="Cultured fibroblasts (kidney)"
                     /geo_loc_name="Mexico: San Felipe, Baja California"
                     /lat_lon="31.103595 N 114.679383 W"
                     /collection_date="04-Nov-2017"
                     /collected_by="Frances Gulland"
     Protein         1..1089
                     /product="platelet-derived growth factor receptor alpha
                     isoform X2"
                     /calculated_mol_wt=122646
     Region          28..100
                     /region_name="Ig_3"
                     /note="Immunoglobulin domain; pfam13927"
                     /db_xref="CDD:464046"
     Region          212..310
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          231..235
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          244..248
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          273..277
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          287..292
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          302..305
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          313..413
                     /region_name="Ig4_PDGFR"
                     /note="Fourth immunoglobulin (Ig)-like domain of
                     platelet-derived growth factor receptor (PDGFR); cd05859"
                     /db_xref="CDD:409445"
     Region          555..956
                     /region_name="PTKc_PDGFR_alpha"
                     /note="Catalytic domain of the Protein Tyrosine Kinase,
                     Platelet Derived Growth Factor Receptor alpha; cd05105"
                     /db_xref="CDD:173653"
     Site            order(599..600,602..605,607,625,627,675,677,681,818,
                     822..823,825,836,854..858,867,902)
                     /site_type="active"
                     /db_xref="CDD:173653"
     Site            order(599..600,602..605,607,625,627,675,677,681,822..823,
                     825,836)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:173653"
     Site            order(818,822,854..858,867,902)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:173653"
     Site            835..860
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:173653"
     CDS             1..1089
                     /gene="PDGFRA"
                     /coded_by="XM_032632083.1:242..3511"
                     /db_xref="GeneID:116754045"
ORIGIN      
        1 mgtshwallv lgclvtgpsl ilcqlslpsi lpsenerivq lnssfslrcf gesevswqyp
       61 mseeenpnve irdeennsgl fvtvlevvsa saahtglytc yynhtqlees eiegrriyiy
      121 vpdpdvafvp lgmtdylviv edddsaiipc rttdpetpvi llssdgvvha sydsrqgfng
      181 tftvgpyice atvrgkkfqt ipfnvyalka tseldlemea lktvykages ivvtcavfnn
      241 evvdlqwtyp gqvkgkgitm leetkvpsik lvytlmvpea tvkdsgdyec aarqatkevk
      301 emkkvtisvh ekgfieikpn fspleavnlh evkhfvvdvq aypppriawl kdnltlienl
      361 teittdieki qeiryrsklk lirakeedsg hytivvqned dvksytfell tqvpssildl
      421 vddhhgsngg qtvrctaegt plpdiewmic kdikkcnnet swtilannvs niitevhprd
      481 rsmvegqvtf akveetiavr claknllgve srelklvapt lrseltvaaa vlvllvivii
      541 slivlvviwk qkpryeirwr viesispdgh eyiyvdpmql pydsrwefpr dglvlgrilg
      601 sgafgkvveg tayglsrsqp vmkvavkmlk ptarssekqa lmselkimth lgphlnivnl
      661 lgactksgpi yiiteycfyg dlvnylhknr dsflsrhpek pkkeldifgl npadestrsy
      721 vilsfenngd ymdmkqadtt qyvpmlerke vskysdiqra lydrpasykk ksmldsevkn
      781 llsddnsegl tlldllsfty qvargmefla skncvhrdla arnvllaqgk ivkicdfgla
      841 rdimhdsnyv skgstflpvk wmapesifdn lyttlsdvws ygillweifs lggtpypgmm
      901 vdstfynkik sgyrmakpdh atsevyeimv kcwnsepekr psfyhlseiv enllpgqykk
      961 syekihldfl ksdhpavarm rvdsdnayig vtykneedkl kdweggldeq rlsadsgyii
     1021 plpdidpvpe eedlgkrnrh ssqtseesai etgsssstfi kredetiedi dmmddigids
     1081 sdlvedsfl
//
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