LOCUS       XP_042179027             564 aa            linear   VRT 08-JUL-2021
DEFINITION  suppressor of cytokine signaling 5-like [Oncorhynchus tshawytscha].
ACCESSION   XP_042179027
VERSION     XP_042179027.1
DBLINK      BioProject: PRJNA432585
DBSOURCE    REFSEQ: accession XM_042323093.1
KEYWORDS    RefSeq.
SOURCE      Oncorhynchus tshawytscha (Chinook salmon)
  ORGANISM  Oncorhynchus tshawytscha
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
            Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_056429.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Oncorhynchus tshawytscha Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 9.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..564
                     /organism="Oncorhynchus tshawytscha"
                     /isolate="Ot180627B"
                     /db_xref="taxon:74940"
                     /sex="male"
                     /tissue_type="blood"
                     /dev_stage="Mature"
                     /geo_loc_name="Canada: British Columbia, Capilano River"
                     /linkage_group="LG01"
     Protein         1..564
                     /product="suppressor of cytokine signaling 5-like"
                     /calculated_mol_wt=62424
     Region          156..199
                     /region_name="SOCS"
                     /note="Suppressor of cytokine signalling; pfam12610"
                     /db_xref="CDD:432667"
     Region          397..497
                     /region_name="SH2"
                     /note="Src homology 2 (SH2) domain; cl15255"
                     /db_xref="CDD:472789"
     Site            order(415,433,454,456)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198173"
     Site            order(455,485)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198173"
     Region          506..562
                     /region_name="SOCS"
                     /note="SOCS (suppressors of cytokine signaling) box. The
                     SOCS box is found in the C-terminal region of CIS/SOCS
                     family proteins (in combination with a SH2 domain), ASBs
                     (ankyrin repeat-containing proteins with a SOCS box), SSBs
                     (SPRY domain-containing proteins...; cl02533"
                     /db_xref="CDD:470605"
     Site            order(507..512,518,525,531)
                     /site_type="active"
                     /note="elongin B/C interaction [active]"
                     /db_xref="CDD:239641"
     CDS             1..564
                     /gene="LOC112253130"
                     /coded_by="XM_042323093.1:561..2255"
                     /db_xref="GeneID:112253130"
ORIGIN      
        1 mekvgkmwsn lrnrcqtlfh sdgagpsten svveedgmhc vadlgrgets geaqaslass
       61 lsrsllplpg vtggrrhncv sdipqmvert tdrkdneear vapwgvpmgr rdsysrhapw
      121 ggkkkhscst ktqssmdtdr rsgrargaag rrerrygvns iqemddsgdg grslstrslr
      181 qrlsdtvglc lplpprrrsl ssspqtptis krkihltelm letcpfpqgs dlankwhlik
      241 qhtapasphs stalldafdp ahpspedeee rlrerrrlsi eegvdpppna qihtlealaq
      301 csslyklgpk mapgiaeasg egkmascsgg aagssvqvlg gataqladcd seedsttlcl
      361 qalrpklrht sgdghlsrnq sgpwkvhtqi dyihclvpdl lqitalpcyw gvmdryeaea
      421 lldgrpegtf llrdsaqedy lfsvsfrryn rslharieqw nhnfsfdahd pcvfhsstvt
      481 gllehykdps acmffepllt aplhrtfpsg lqhlaraaic rrttydgigt lplppalqdf
      541 lkeyhykqkv rvrwlerepp lkvk
//