LOCUS       XP_044085812             441 aa            linear   MAM 13-OCT-2021
DEFINITION  suppressor of cytokine signaling 4 [Neogale vison].
ACCESSION   XP_044085812
VERSION     XP_044085812.1
DBLINK      BioProject: PRJNA769404
DBSOURCE    REFSEQ: accession XM_044229877.1
KEYWORDS    RefSeq.
SOURCE      Neogale vison (American mink)
  ORGANISM  Neogale vison
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia;
            Musteloidea; Mustelidae; Mustelinae; Neogale.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_058103.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Neovison vison Annotation Release
                                           100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 9.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Neogale vison"
                     /isolate="M4711"
                     /db_xref="taxon:452646"
                     /chromosome="13"
                     /sex="female"
                     /tissue_type="tongue"
                     /dev_stage="mature"
     Protein         1..441
                     /product="suppressor of cytokine signaling 4"
                     /calculated_mol_wt=50212
     Region          58..109
                     /region_name="SOCS"
                     /note="Suppressor of cytokine signalling; pfam12610"
                     /db_xref="CDD:432667"
     Region          277..377
                     /region_name="SH2_SOCS4"
                     /note="Src homology 2 (SH2) domain found in suppressor of
                     cytokine signaling (SOCS) proteins; cd10385"
                     /db_xref="CDD:198248"
     Site            order(285,287)
                     /site_type="other"
                     /note="Elongin-C binding interface [polypeptide binding]"
                     /db_xref="CDD:198248"
     Site            order(295,313,315,323,336)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198248"
     Site            order(346,348,366)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198248"
     Region          386..440
                     /region_name="SOCS_SOCS4"
                     /note="SOCS (suppressors of cytokine signaling) box of
                     SOCS4-like proteins. Together with CIS1, the CIS/SOCS
                     family of proteins is characterized by the presence of a
                     C-terminal SOCS box and a central SH2 domain. The general
                     function of the SOCS box is the...; cd03738"
                     /db_xref="CDD:239707"
     Site            order(387..392,398,405,411,416)
                     /site_type="other"
                     /note="putative elongin B/C interaction [polypeptide
                     binding]"
                     /db_xref="CDD:239707"
     CDS             1..441
                     /gene="SOCS4"
                     /coded_by="XM_044229877.1:375..1700"
                     /db_xref="GeneID:122893081"
ORIGIN      
        1 maensesisk nvdvrpktsr srsadrkdgy vwsgkklsws kksescsdae tvnavektev
       61 plrsqerkhs cssieldldh scghrflgrs lkqklqdavg qcfpikncsg rhssglpskr
      121 kihiselmld kcpfpprsdl afrwhfikrh tapinsksse wvstdssqse lrdgqlkqrr
      181 nveeevncfs qtnvqpcvit tnsasscrgg pvtgsvmnll snnsiedsdm dsddeiitlc
      241 tssrkrnkpk wemdeeilql etppkyhtqi dyvhclvpdl lqinnnpcyw gvmdkyaaea
      301 llegkpegtf llrdsaqedy lfsvsfrrys rslharieqw nhnfsfdahd pcvfhspdit
      361 gllehykdps acmffeplls tplirtfpfs lqhicrtvic ncttydgida lpipssmkly
      421 lkeyhykskv rvlridapeq c
//