LOCUS       XP_066854708             436 aa            linear   VRT 01-AUG-2024
DEFINITION  suppressor of cytokine signaling 4 [Anser cygnoides].
ACCESSION   XP_066854708
VERSION     XP_066854708.1
DBLINK      BioProject: PRJNA1136952
DBSOURCE    REFSEQ: accession XM_066998607.1
KEYWORDS    RefSeq.
SOURCE      Anser cygnoides (Swan goose)
  ORGANISM  Anser cygnoides
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes;
            Anatidae; Anserinae; Anser.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_089877) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_040182565.1-RS_2024_07
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 07/23/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Anser cygnoides"
                     /isolate="HZ-2024a"
                     /db_xref="taxon:8845"
                     /chromosome="5"
                     /sex="female"
                     /tissue_type="blood"
                     /geo_loc_name="China: Taizhou"
                     /collection_date="2022-10"
                     /breed="goose"
     Protein         1..436
                     /product="suppressor of cytokine signaling 4"
                     /calculated_mol_wt=49529
     Region          65..111
                     /region_name="SOCS"
                     /note="Suppressor of cytokine signalling; pfam12610"
                     /db_xref="CDD:432667"
     Region          271..371
                     /region_name="SH2_SOCS4"
                     /note="Src homology 2 (SH2) domain found in suppressor of
                     cytokine signaling (SOCS) proteins; cd10385"
                     /db_xref="CDD:198248"
     Site            order(279,281)
                     /site_type="other"
                     /note="Elongin-C binding interface [polypeptide binding]"
                     /db_xref="CDD:198248"
     Site            order(289,307,309,317,330)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198248"
     Site            order(340,342,360)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198248"
     Region          380..435
                     /region_name="SOCS_SOCS4"
                     /note="SOCS (suppressors of cytokine signaling) box of
                     SOCS4-like proteins. Together with CIS1, the CIS/SOCS
                     family of proteins is characterized by the presence of a
                     C-terminal SOCS box and a central SH2 domain. The general
                     function of the SOCS box is the...; cd03738"
                     /db_xref="CDD:239707"
     Site            order(381..386,392,399,405,410)
                     /site_type="other"
                     /note="putative elongin B/C interaction [polypeptide
                     binding]"
                     /db_xref="CDD:239707"
     CDS             1..436
                     /gene="SOCS4"
                     /coded_by="XM_066998607.1:260..1570"
                     /db_xref="GeneID:106044059"
ORIGIN      
        1 madskdsnvk nadvrpkssr srsadrkdgy vwsgkklsws kksehcsdae tasaagrsgs
       61 nlksqerkys cssieldldr scghrflgrs lkqklqdavg qcfpikncss rhasglqskr
      121 kihiselmld kcpfpprsel afrwhlikrh tapisqkaed wiiadlsqne ekedhlrdde
      181 vanggtdsps qscdladgis srgdsrselv lgkvvrsske esdmdsddev itlctssrkr
      241 nkpkwetdde llrmetppky htqidyvhcl vpdllqinnn pcywgvmdky aaeallegkp
      301 egtfllrdsa qedylfsvsf rrysrslhar ieqwnhnfsf dahdpcvfhs pditgllehy
      361 kdpsscmffe pllstplnrt fpfslqhicr tvicncttyd gidalpipps vklylkeyhy
      421 kskvrvlrid vpeqqs
//