KEGG   Candidatus Saccharibacteria bacterium GW2011_GWC2_44_17: UW38_C0001G0374
Entry
UW38_C0001G0374   CDS       T04605                                 
Symbol
ligA
Name
(GenBank) ligase, NAD-dependent protein
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
sbag  Candidatus Saccharibacteria bacterium GW2011_GWC2_44_17
Pathway
sbag03030  DNA replication
sbag03410  Base excision repair
sbag03420  Nucleotide excision repair
sbag03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:sbag00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    UW38_C0001G0374 (ligA)
   03410 Base excision repair
    UW38_C0001G0374 (ligA)
   03420 Nucleotide excision repair
    UW38_C0001G0374 (ligA)
   03430 Mismatch repair
    UW38_C0001G0374 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:sbag03032]
    UW38_C0001G0374 (ligA)
   03400 DNA repair and recombination proteins [BR:sbag03400]
    UW38_C0001G0374 (ligA)
Enzymes [BR:sbag01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     UW38_C0001G0374 (ligA)
DNA replication proteins [BR:sbag03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     UW38_C0001G0374 (ligA)
DNA repair and recombination proteins [BR:sbag03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     UW38_C0001G0374 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     UW38_C0001G0374 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     UW38_C0001G0374 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      UW38_C0001G0374 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 HHH Nlig-Ia PTCB-BRCT RNA_ligase UPF0758_N
Other DBs
NCBI-ProteinID: AKM80235
UniProt: A0A0G4AYB0
Position
complement(320885..322906)
AA seq 673 aa
MMTPVPHDKARLEELRELIDQYSYEYHVNDEQSVSDAVYDSLFGEIKQIEAAHPEWITSE
SPTQRVGNELKDGFKKVAHSSRMLSLNDVFDREEVQAWVTRIDKLLPGARHEFFVDVKMD
GLACALIYQDGNLVQAITRGDSYVGEDVTNNVRTIKNIPLRLRGQSKYAAFLQGRTEIRG
EIVMLKTDFAMLNTQRRENGEPEFANPRNLAAGTIRQLDPRLVAARPLHFRAYDLLRDNP
DEVPTNMFAYEALSGLGVTRNKEATVFTQLPDVMRFVDHIGDVRENLPFNTDGLVIKVND
RAVFRELGIVGKQPRAAVAYKYAAEQATTVVKDIVISIGRTGAATPVAVFDPVVVAGSTV
QHASLHNADEIARKDVRVGDTVIIFKAGDIIPQVEAVVLELRPKDSEQFDYQKALAQQYP
ELEFERTGKDVVYRVKGANTDLMLKRAVEYYASKAALDIETLGEKNVVALVDAGLVKDLA
DIYTLSIDDLLKLDRFADISAKKLVNAIAEKKNPPLEKFILALGIRHVGAQTAIDLANKF
GSMDKLQRARIEQLEDIDGIGKVVAESVVAWFADEDNIALLEKFERVGVHPHFQKKMGRL
IGKSFVITGSLESMSRDQAADRIRALGGTFQTSVAKDTIYLVAGGKVGASKLKKAESYGT
KIIDEAALLNLIS
NT seq 2022 nt   +upstreamnt  +downstreamnt
atgatgacgccagtcccgcatgataaggcacgactcgaagaactacgcgaactgattgat
cagtatagctatgagtaccatgtcaatgacgagcagtcggtcagtgatgctgtgtacgat
agtctattcggtgaaattaagcagattgaagcagcgcatccagaatggataacatccgag
agtccaactcaaagagtcggaaatgaactcaaagatggctttaaaaaggttgctcatagt
agccgaatgcttagcctaaatgatgtgtttgatcgagaggaagttcaggcgtgggtgacg
cgtatagacaagctgcttccaggtgcacgacatgagttttttgttgatgtgaaaatggac
ggtttagcgtgtgcacttatttatcaagatggaaatttagtgcaagcgattacgcgtgga
gatagttacgtaggtgaagatgtgacgaacaatgttcgtactataaaaaatattccactg
cgactacgaggtcagtctaaatacgctgcgttcttacagggccgtacagagatacgcggc
gaaattgtcatgctaaagactgactttgctatgttgaatacacagcgtagagaaaatgga
gagccggaatttgcaaatccaagaaacctagcagctggtacgattcgacaacttgatcca
cgacttgttgcggcacgtccacttcattttcgcgcgtatgatttattgcgcgacaacccg
gatgaagtgccgaccaatatgtttgcatatgaggcactctctggcctcggggtgacccgt
aataaagaggcgacagtatttactcaactacctgatgttatgcggtttgtagatcatatc
ggtgatgtccgcgaaaacttgccatttaatactgacggacttgtcataaaagtaaatgat
agggcggtctttcgagagcttggaattgtcgggaagcagcctagggcggccgtagcatac
aaatacgctgcagagcaggcgacaaccgtcgtaaaagatattgtgattagtattggacgc
accggagcagctacacctgttgcggtattcgacccggtagtggttgctggatcgacggtg
caacacgcgagtctccataatgcggatgaaattgcacgaaaagacgtacgcgtaggtgat
acggttattatattcaaggctggtgacattattcctcaggtagaagctgtcgtgcttgag
cttaggccaaaagatagtgagcaatttgactatcaaaaggcgctcgctcagcaataccct
gagctggagtttgaacgtactggcaaggacgtcgtatatcgtgtcaaaggcgcaaatact
gaccttatgctcaaacgtgcggtcgaatactatgcgagtaaagctgcgcttgatatcgag
actctgggagagaagaatgttgtcgcacttgtagacgctggtcttgtgaaggaccttgcc
gacatttacactttaagcatcgacgacctcctgaagctagatcgttttgcggatatatcg
gcaaaaaaactcgtcaatgcaattgcagagaagaagaatccgccactcgagaagtttatt
cttgctcttggtattcgccatgttggtgcgcaaactgctattgatcttgcaaataagttt
ggaagcatggataagctgcagcgagcacgcatagagcagcttgaagatatcgatggtatc
ggtaaggttgtcgcagagtcggtagtagcctggtttgctgatgaggataacattgcgcta
cttgagaagtttgaacgagttggtgtgcatccacatttccaaaagaaaatgggtagatta
attggaaagagttttgtcattaccggtagtctcgagagcatgagccgtgatcaggcggct
gatcggattcgtgcgcttggaggaacgtttcagacttcagtagcaaaagatacgatttat
cttgtcgctggcggaaaagtcggcgcgagtaagctgaagaaagctgaaagttacggaaca
aaaataattgatgaggctgcgctgctaaacttgatatcatga

  All links  
Gene (11)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (10)   
   Pfam (10)   
All databases (22)   

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