KEGG   Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101029401
Entry
101029401         CDS       T04350                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
sbq  Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq00562  Inositol phosphate metabolism
sbq01100  Metabolic pathways
sbq04015  Rap1 signaling pathway
sbq04020  Calcium signaling pathway
sbq04022  cGMP-PKG signaling pathway
sbq04062  Chemokine signaling pathway
sbq04070  Phosphatidylinositol signaling system
sbq04071  Sphingolipid signaling pathway
sbq04072  Phospholipase D signaling pathway
sbq04081  Hormone signaling
sbq04082  Neuroactive ligand signaling
sbq04261  Adrenergic signaling in cardiomyocytes
sbq04270  Vascular smooth muscle contraction
sbq04310  Wnt signaling pathway
sbq04371  Apelin signaling pathway
sbq04540  Gap junction
sbq04611  Platelet activation
sbq04613  Neutrophil extracellular trap formation
sbq04621  NOD-like receptor signaling pathway
sbq04713  Circadian entrainment
sbq04720  Long-term potentiation
sbq04723  Retrograde endocannabinoid signaling
sbq04724  Glutamatergic synapse
sbq04725  Cholinergic synapse
sbq04726  Serotonergic synapse
sbq04728  Dopaminergic synapse
sbq04730  Long-term depression
sbq04742  Taste transduction
sbq04750  Inflammatory mediator regulation of TRP channels
sbq04911  Insulin secretion
sbq04912  GnRH signaling pathway
sbq04915  Estrogen signaling pathway
sbq04916  Melanogenesis
sbq04918  Thyroid hormone synthesis
sbq04919  Thyroid hormone signaling pathway
sbq04921  Oxytocin signaling pathway
sbq04922  Glucagon signaling pathway
sbq04924  Renin secretion
sbq04925  Aldosterone synthesis and secretion
sbq04926  Relaxin signaling pathway
sbq04927  Cortisol synthesis and secretion
sbq04928  Parathyroid hormone synthesis, secretion and action
sbq04929  GnRH secretion
sbq04933  AGE-RAGE signaling pathway in diabetic complications
sbq04934  Cushing syndrome
sbq04935  Growth hormone synthesis, secretion and action
sbq04961  Endocrine and other factor-regulated calcium reabsorption
sbq04970  Salivary secretion
sbq04971  Gastric acid secretion
sbq04972  Pancreatic secretion
sbq04973  Carbohydrate digestion and absorption
sbq05010  Alzheimer disease
sbq05016  Huntington disease
sbq05017  Spinocerebellar ataxia
sbq05022  Pathways of neurodegeneration - multiple diseases
sbq05142  Chagas disease
sbq05143  African trypanosomiasis
sbq05146  Amoebiasis
sbq05163  Human cytomegalovirus infection
sbq05200  Pathways in cancer
sbq05415  Diabetic cardiomyopathy
sbq05417  Lipid and atherosclerosis
Module
sbq_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:sbq00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101029401 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101029401 (PLCB3)
   04310 Wnt signaling pathway
    101029401 (PLCB3)
   04371 Apelin signaling pathway
    101029401 (PLCB3)
   04020 Calcium signaling pathway
    101029401 (PLCB3)
   04070 Phosphatidylinositol signaling system
    101029401 (PLCB3)
   04072 Phospholipase D signaling pathway
    101029401 (PLCB3)
   04071 Sphingolipid signaling pathway
    101029401 (PLCB3)
   04022 cGMP-PKG signaling pathway
    101029401 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    101029401 (PLCB3)
   04081 Hormone signaling
    101029401 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101029401 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101029401 (PLCB3)
   04613 Neutrophil extracellular trap formation
    101029401 (PLCB3)
   04621 NOD-like receptor signaling pathway
    101029401 (PLCB3)
   04062 Chemokine signaling pathway
    101029401 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    101029401 (PLCB3)
   04922 Glucagon signaling pathway
    101029401 (PLCB3)
   04929 GnRH secretion
    101029401 (PLCB3)
   04912 GnRH signaling pathway
    101029401 (PLCB3)
   04915 Estrogen signaling pathway
    101029401 (PLCB3)
   04921 Oxytocin signaling pathway
    101029401 (PLCB3)
   04926 Relaxin signaling pathway
    101029401 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    101029401 (PLCB3)
   04918 Thyroid hormone synthesis
    101029401 (PLCB3)
   04919 Thyroid hormone signaling pathway
    101029401 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    101029401 (PLCB3)
   04916 Melanogenesis
    101029401 (PLCB3)
   04924 Renin secretion
    101029401 (PLCB3)
   04925 Aldosterone synthesis and secretion
    101029401 (PLCB3)
   04927 Cortisol synthesis and secretion
    101029401 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101029401 (PLCB3)
   04270 Vascular smooth muscle contraction
    101029401 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    101029401 (PLCB3)
   04971 Gastric acid secretion
    101029401 (PLCB3)
   04972 Pancreatic secretion
    101029401 (PLCB3)
   04973 Carbohydrate digestion and absorption
    101029401 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    101029401 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    101029401 (PLCB3)
   04725 Cholinergic synapse
    101029401 (PLCB3)
   04728 Dopaminergic synapse
    101029401 (PLCB3)
   04726 Serotonergic synapse
    101029401 (PLCB3)
   04720 Long-term potentiation
    101029401 (PLCB3)
   04730 Long-term depression
    101029401 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    101029401 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    101029401 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    101029401 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101029401 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101029401 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101029401 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101029401 (PLCB3)
   05142 Chagas disease
    101029401 (PLCB3)
   05143 African trypanosomiasis
    101029401 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101029401 (PLCB3)
   05016 Huntington disease
    101029401 (PLCB3)
   05017 Spinocerebellar ataxia
    101029401 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    101029401 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101029401 (PLCB3)
   05415 Diabetic cardiomyopathy
    101029401 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101029401 (PLCB3)
   04934 Cushing syndrome
    101029401 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sbq04131]
    101029401 (PLCB3)
Enzymes [BR:sbq01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101029401 (PLCB3)
Membrane trafficking [BR:sbq04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    101029401 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    101029401 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PI-PLC-Y PLCB1-4-like_EFh PH_14 EF-hand_like C2
Other DBs
NCBI-GeneID: 101029401
NCBI-ProteinID: XP_010346545
UniProt: A0A2K6V229
Position
Unknown
AA seq 1175 aa
MEVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVSGPDPVNTVFL
NFMAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKM
FSADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGK
PYLTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNKQFLERDQMSMEGFSR
YLGGEENGILPLEALDLSADMTQPLSSYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGC
RCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDS
AKQQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHQPSTGGP
DSAGRKRPLEQSNSALSESSATTEPSSPQLGSPSSDSCPGLSNGEEGVLEKPSLELQKSL
GEEGLNRGPYALGPADREEEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIE
PVKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSN
YMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEV
IVDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDE
EPFAFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPAL
LIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRARQLAALIGESEAQAGHETCQDTQSQ
QLGSQLSPNPSPSPLDASPRRPPGPATSPTSASLSSPGQRDDLIASILSEVAPTPLDELR
GHKALVKLRSRQERELRELRKKHQRKAVTLTRRLLDGLAQAQAEGRCRPRPGALGGAAEE
DSKEGEDEAKRYQEFQSRQVQSLLGLREAQADAEARRRLEHLKQAQQRLREVVLDANTTQ
FKRLKETNEREKKELQKILDRKRHNSISEAKTRDKHKKEVELTEINRRHITESVNSIRRL
EEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLAQECQEHRARLPQEIRRSLLGETPEGL
GDRPLVACASNGHAPGSSGHLSGADSESQEENTQL
NT seq 3528 nt   +upstreamnt  +downstreamnt
atggaggtggacacactggacatcagttccatcagggacacacggacgggccggtacgcc
cgcctgcccaaggatcccaagatccgggaagttctgggctttgggggtcccgacgcccgg
ctggaggagaagctgatgacggtggtgtctgggccggaccccgtgaacacagtgttcttg
aacttcatggccgtgcaggacgatacagccaaggtctggtccgaggagctgttcaagctg
gctatgaacatcctggctcagaacgcctcccggaacaccttcctgcgcaaagcatacacg
aagctgaagctgcaggtgaaccaggatggtcggatccccgtcaagaacatcctgaagatg
ttctcagccgacaagaagcgagtagagactgcgctggaatcctgtggcctcaacttcaac
cggagtgagtccatccgacccgatgagttttccttggaaatctttgagcggtttctgaac
aagctgtgtctgcggccggacattgacaagatcctgctggagataggtgccaagggcaag
ccatacctgacgctggagcagctcatggacttcatcaaccagaagcaacgtgacccgaga
ctcaacgaagtgctgtacccacccctgcggccctcccaagcccggctgctcattgagaag
tatgagcccaacaagcagtttctggagcgagaccagatgtccatggagggctttagccga
tacctgggaggcgaggagaatggtatcctgcccctggaagctctggatctgagtgcagac
atgacccagccgctgagctcctacttcatcaactcctcgcataacacctatctcactgcg
gggcagctggctgggacctcgtcagtggagatgtaccgccaggccctgctctggggctgc
cgctgcgtggagctggacgtgtggaaggggcggccgcccgaggaggagcccttcatcacc
catggcttcaccatgaccacggaggtgcctctgcgagacgtgctggaggccattgctgag
actgccttcaagacctctccctaccccgtcatcctctcctttgagaaccacgtggattcg
gcaaagcagcaggcaaagatggccgagtactgccgctccatctttggagatgcgctgctt
atcgaccctctggacaagtacccgctggccccaggcgtccctctgcccagcccccaggac
ctgatgggccgaatcctggtgaagaacaagaagcggcaccagccgagcaccggcggccca
gacagtgccgggcgcaagcggccactggagcagagcaactcggccctgagcgagagctcc
gccaccaccgagccctcctccccgcagcttgggtctcccagctctgacagctgcccaggc
ctgagcaatggggaggagggggtgctcgagaagcccagcctggagcttcaaaaatctttg
ggcgaggagggcctgaaccggggcccctatgctcttggacctgctgaccgtgaggaggag
gaggaagatgaggaagaagaggaacagacagaccccaaaaagccaaccacagatgagggc
acagctagcagcgaggtcaatgccactgaggagatgtccacgcttgtcaactacatcgag
cctgtcaagttcaagtcctttgaggctgctcgaaagaggaacaaatgcttcgagatgtca
tccttcgtggagaccaaggccatggagcagctgaccaagagccccatggagtttgtggaa
tacaacaagcagcagctcagccgcatctaccccaagggcacccgcgtggactcctccaac
tacatgccccagctcttctggaacgtagggtgccagcttgtcgcgctcaacttccagacc
ctggatgtggcgatgcagctcaatgcgggcgtgttcgagtacaatgggcgcagcgggtac
ctgctcaagccggagttcatgcggcggccggacaagtccttcgaccccttcaccgaagtc
atcgtcgatggcatcgtggccaatgccttgcgggtcaaggtgatctcggggcagttcctg
tccgacaggaaggtgggcatctacgtggaggtggacatgtttggcctccccgttgacacg
cggcgcaagtaccgcacccggacctctcaggggaactccttcaaccccgtgtgggacgag
gagccgttcgccttccccaaggtggtgctgcccacgctggcttcgcttcgcatcgcagcc
tttgaggagggcggcaaattcgtggggcaccggatcctgcctgtctctgccatccgctcc
gggtaccactacgtctgcctgcggaacgaggccaaccaaccgctgtgcctgccggccctg
ctcatctacaccgaggcctcggactacattccggacgaccaccaggactacgcggaggcc
ttgatcaaccccattaagcacgtcagcctgatggaccagagagcccgccaactggctgcc
ctcattggtgagagtgaggctcaggctggccacgagacatgccaggacacccagtctcag
cagctggggtctcagctgtccccaaaccccagtcctagcccactggatgcttccccacgc
cggccccccggccctgccacctcccctaccagcgcctctctgagcagcccagggcagcgc
gacgatctcatcgccagcatcctctcagaggtggcccccaccccgctggacgagctccga
ggacacaaggctctggtcaagctccggagccggcaggagcgagagcttcgggagctgcgc
aagaagcatcagcggaaggcggtcaccctcacccgccgcctgctggatggcctggctcag
gcacaggcggagggcaggtgccggccgcggccaggtgccctaggtggggctgctgaagag
gactcaaaggagggggaggacgaggcgaagcgctatcaggagttccagagcagacaggtg
cagagcctactggggctgcgggaggcccaggcggacgcagaggcgcggcggaggctggag
cacctgaaacaggctcagcagcggctcagggaggtcgtccttgatgcaaacacgactcag
ttcaagaggctgaaggagacgaacgagagggagaagaaggagctgcagaagatcctggac
agaaagcgccacaacagcatctcggaggccaagacaagggacaagcataagaaggaggtg
gaactgacagagattaatcgtcggcacatcactgagtctgtcaactccatccgtcggctg
gaggaggcccagaagcagcggcacgaccgtcttgtggcgggccagcagcaggttctgcaa
cagctggcagaagaggagcccaagctgctggctcagctggcccaggagtgtcaggagcat
cgggcaaggctgccccaggagatccgccggagcctgctgggcgagacgccagaggggctg
ggggacaggcctctggtggcctgtgccagcaacggtcacgcacccgggagcagcgggcac
ctgtcgggtgctgactcggagagccaggaggagaacacgcagctctga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (15)   

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