KEGG   Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101047168
Entry
101047168         CDS       T04350                                 
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
sbq  Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq00562  Inositol phosphate metabolism
sbq01100  Metabolic pathways
sbq04015  Rap1 signaling pathway
sbq04020  Calcium signaling pathway
sbq04022  cGMP-PKG signaling pathway
sbq04062  Chemokine signaling pathway
sbq04070  Phosphatidylinositol signaling system
sbq04071  Sphingolipid signaling pathway
sbq04072  Phospholipase D signaling pathway
sbq04081  Hormone signaling
sbq04082  Neuroactive ligand signaling
sbq04261  Adrenergic signaling in cardiomyocytes
sbq04270  Vascular smooth muscle contraction
sbq04310  Wnt signaling pathway
sbq04371  Apelin signaling pathway
sbq04540  Gap junction
sbq04611  Platelet activation
sbq04613  Neutrophil extracellular trap formation
sbq04621  NOD-like receptor signaling pathway
sbq04713  Circadian entrainment
sbq04720  Long-term potentiation
sbq04723  Retrograde endocannabinoid signaling
sbq04724  Glutamatergic synapse
sbq04725  Cholinergic synapse
sbq04726  Serotonergic synapse
sbq04728  Dopaminergic synapse
sbq04730  Long-term depression
sbq04742  Taste transduction
sbq04750  Inflammatory mediator regulation of TRP channels
sbq04911  Insulin secretion
sbq04912  GnRH signaling pathway
sbq04915  Estrogen signaling pathway
sbq04916  Melanogenesis
sbq04918  Thyroid hormone synthesis
sbq04919  Thyroid hormone signaling pathway
sbq04921  Oxytocin signaling pathway
sbq04922  Glucagon signaling pathway
sbq04924  Renin secretion
sbq04925  Aldosterone synthesis and secretion
sbq04926  Relaxin signaling pathway
sbq04927  Cortisol synthesis and secretion
sbq04928  Parathyroid hormone synthesis, secretion and action
sbq04929  GnRH secretion
sbq04933  AGE-RAGE signaling pathway in diabetic complications
sbq04934  Cushing syndrome
sbq04935  Growth hormone synthesis, secretion and action
sbq04961  Endocrine and other factor-regulated calcium reabsorption
sbq04970  Salivary secretion
sbq04971  Gastric acid secretion
sbq04972  Pancreatic secretion
sbq04973  Carbohydrate digestion and absorption
sbq05010  Alzheimer disease
sbq05016  Huntington disease
sbq05017  Spinocerebellar ataxia
sbq05022  Pathways of neurodegeneration - multiple diseases
sbq05142  Chagas disease
sbq05143  African trypanosomiasis
sbq05146  Amoebiasis
sbq05163  Human cytomegalovirus infection
sbq05200  Pathways in cancer
sbq05415  Diabetic cardiomyopathy
sbq05417  Lipid and atherosclerosis
Module
sbq_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:sbq00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101047168 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101047168 (PLCB1)
   04310 Wnt signaling pathway
    101047168 (PLCB1)
   04371 Apelin signaling pathway
    101047168 (PLCB1)
   04020 Calcium signaling pathway
    101047168 (PLCB1)
   04070 Phosphatidylinositol signaling system
    101047168 (PLCB1)
   04072 Phospholipase D signaling pathway
    101047168 (PLCB1)
   04071 Sphingolipid signaling pathway
    101047168 (PLCB1)
   04022 cGMP-PKG signaling pathway
    101047168 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    101047168 (PLCB1)
   04081 Hormone signaling
    101047168 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101047168 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101047168 (PLCB1)
   04613 Neutrophil extracellular trap formation
    101047168 (PLCB1)
   04621 NOD-like receptor signaling pathway
    101047168 (PLCB1)
   04062 Chemokine signaling pathway
    101047168 (PLCB1)
  09152 Endocrine system
   04911 Insulin secretion
    101047168 (PLCB1)
   04922 Glucagon signaling pathway
    101047168 (PLCB1)
   04929 GnRH secretion
    101047168 (PLCB1)
   04912 GnRH signaling pathway
    101047168 (PLCB1)
   04915 Estrogen signaling pathway
    101047168 (PLCB1)
   04921 Oxytocin signaling pathway
    101047168 (PLCB1)
   04926 Relaxin signaling pathway
    101047168 (PLCB1)
   04935 Growth hormone synthesis, secretion and action
    101047168 (PLCB1)
   04918 Thyroid hormone synthesis
    101047168 (PLCB1)
   04919 Thyroid hormone signaling pathway
    101047168 (PLCB1)
   04928 Parathyroid hormone synthesis, secretion and action
    101047168 (PLCB1)
   04916 Melanogenesis
    101047168 (PLCB1)
   04924 Renin secretion
    101047168 (PLCB1)
   04925 Aldosterone synthesis and secretion
    101047168 (PLCB1)
   04927 Cortisol synthesis and secretion
    101047168 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101047168 (PLCB1)
   04270 Vascular smooth muscle contraction
    101047168 (PLCB1)
  09154 Digestive system
   04970 Salivary secretion
    101047168 (PLCB1)
   04971 Gastric acid secretion
    101047168 (PLCB1)
   04972 Pancreatic secretion
    101047168 (PLCB1)
   04973 Carbohydrate digestion and absorption
    101047168 (PLCB1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    101047168 (PLCB1)
  09156 Nervous system
   04724 Glutamatergic synapse
    101047168 (PLCB1)
   04725 Cholinergic synapse
    101047168 (PLCB1)
   04728 Dopaminergic synapse
    101047168 (PLCB1)
   04726 Serotonergic synapse
    101047168 (PLCB1)
   04720 Long-term potentiation
    101047168 (PLCB1)
   04730 Long-term depression
    101047168 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    101047168 (PLCB1)
  09157 Sensory system
   04742 Taste transduction
    101047168 (PLCB1)
   04750 Inflammatory mediator regulation of TRP channels
    101047168 (PLCB1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101047168 (PLCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101047168 (PLCB1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101047168 (PLCB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101047168 (PLCB1)
   05142 Chagas disease
    101047168 (PLCB1)
   05143 African trypanosomiasis
    101047168 (PLCB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101047168 (PLCB1)
   05016 Huntington disease
    101047168 (PLCB1)
   05017 Spinocerebellar ataxia
    101047168 (PLCB1)
   05022 Pathways of neurodegeneration - multiple diseases
    101047168 (PLCB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101047168 (PLCB1)
   05415 Diabetic cardiomyopathy
    101047168 (PLCB1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101047168 (PLCB1)
   04934 Cushing syndrome
    101047168 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sbq04131]
    101047168 (PLCB1)
Enzymes [BR:sbq01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101047168 (PLCB1)
Membrane trafficking [BR:sbq04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    101047168 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    101047168 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 101047168
NCBI-ProteinID: XP_003933260
UniProt: A0A2K6T749
Position
Unknown
AA seq 1216 aa
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLAKKGQISVDGFMRYLS
GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
KLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
EADPGETPSEAPSEARTTPAENGVNHTTSLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPPSLSSDPGKVNHKTPSS
EELGGDIPGKEFDTPL
NT seq 3651 nt   +upstreamnt  +downstreamnt
atggccggggctcaacccggagtgcacgccttgcaactcaagcccgtgtgcgtgtccgac
agcctcaagaagggcaccaaattcgtcaagtgggatgatgattcaactattgttactcca
attattttgaggactgaccctcagggatttttcttttattggacagatcaaaataaggag
acggagctactggatctcagccttgtcaaagatgccagatgtgggagacacgccaaagct
cccaaggaccccaaattacgtgaacttttggacgtggggaacatcggacgcctggagcag
cgcatgatcacagtggtgtatgggcctgacctcgtcaacatctcccatttgaatctcgtg
gctttccaagaagaagtagccaaggaatggacaaatgaggttttcagtttggcaacaaac
ctgctggcccaaaacatgtccagggatgcatttctggaaaaagcctatactaaacttaag
ctgcaagtcactccagaagggcgtattcctctcaaaaacatatatcgcttgttttcagca
gaccggaagcgagttgaaactgctttagaggcttgtagtcttccatcttcaaggaatgat
tcaatacctcaagaagatttcactccagaagtgtacagagttttcctgaacaacctttgc
cctcgacctgaaattgataacatcttttcagaatttggtgccaaaagcaaaccatacctt
acggttgatcagatgatggattttatcaaccttaagcagcgagatcctcggcttaatgaa
atactttatccacctctaaaacaagagcaagtccaagtattgattgagaaatatgaaccc
aacaacagcctcgccaaaaaaggacagatatcagtggatgggttcatgcgctatctgagt
ggagaagaaaacggagtcgtttcacctgagaaactggatttgaacgaagacatgtctcag
cccctttctcactatttcattaattcctcgcacaacacctacctcacagctggccaactg
gctggaaactcctctgttgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtg
gagctggactgctggaagggacggactgcagaagaggaacctgtcatcacccatggcttc
accatgacaactgaaatatctttcaaggaagtgatagaggcaattgcggagtgcgcgttc
aagacttcaccttttccaattctcctttcatttgagaaccatgtggattccccaaagcag
caagccaagatggcggaatattgccgactgatctttggggatgcccttctcatggagccc
ctggaaaaatatccgctcgaatctggagttcctcttccaagtcctatggatttaatgtat
aaaattttggtgaaaaataagaagaaatcacacaagtcatcagaaggaagtggcaaaaag
aagctctcagaacaagcctccaacacctacagtgactcctccagtgtgttcgagccctca
tccccaggagccggagaagctgatacggaaagtgacgatgatgatgatgacgatgactgt
aaaaaatcttcaatggatgaggggactgctggaagcgaggctatggccacagaagaaatg
tctaacctggtgaactacattcagccggtcaagtttgagtcatttgaaatttcaaaaaaa
agaaataaaagtttcgaaatgtcttccttcgtggaaaccaaaggacttgaacaacttacc
aagtctcccgtggaatttgtagaatataacaaaatgcagcttagcaggatatatccgaaa
ggaacacgtgtggattcatccaactatatgcctcagctcttctggaatgcaggttgtcag
atggtggcacttaatttccagacaatggacctggctatgcaaataaatatgggcatgtat
gaatacaacgggaagagtggctacagattgaagccagaattcatgaggaggcctgacaag
cattttgatccatttactgaaggcatcgtagatgggatagtagcaaacactttatctgtt
aagattatttcaggtcagtttctttctgataagaaagttgggacttacgtggaagtggat
atgtttggtttgcctgtggatacaaggaggaaggcatttaagacaaagacatcccaagga
aatgctgtgaatcccgtctgggaagaagaacctattgtgttcaaaaaggtggttcttcct
actctggcctgtttgagaatagcagtttatgaagaaggaggtaaatttattggccaccgt
atcttgccagtgcaagccattcgaccaggctatcactatatctgcctaaggaatgaaagg
aaccagcctctgacgctgcctgctgtctttgtctacatagaagtgaaagactatgtgcca
gacacatatgcagatgtcattgaagctttatcaaacccaatccgatatgtgaacctgatg
gagcagagagcgaagcagttggctgctttgacactagaagatgaagaagaagtaaagaaa
gaggctgatcctggagaaacaccatcagaggctccaagtgaagcaaggacgactccagca
gaaaatggggtgaatcacactacatccctgacacccaagccaccctcccaggctctccac
agccagccagctccaggttctgtaaaagcacctgccaaaacagaagatcttattcaaagt
gtcttaacagaagtggaagcacagaccatcgaagagctaaagcaacagaaatcgtttgtg
aaacttcaaaagaagcactacaaagaaatgaaagacctggttaagaggcaccacaagaaa
accactgaccttatcaaagaacacactacaaagtataatgagattcagaatgactacctg
agaaggagagcagctttggaaaagtctgccaaaaaggacagtaagaaaaaatcagaaccc
agcagccctgatcatggttcgtcaacaattgagcaagacctcgctgccctggatgctgaa
atgacccaaaagttaattgacttaaaggacaaacaacagcagcagctgcttaatcttcgg
caagaacagtattatagtgaaaaataccagaagcgagaacatattaaactgcttattcaa
aaattgacagatgtcgcagaagagtgtcagaacaatcagttaaagaagctcaaagaaatc
tgtgagaaagaaaagaaggaattaaagaagaaaatggataaaaagaggcaggagaagata
acagaagctaaatccaaagacaaaagtcagatggaagaggagaagacagagatgattcgg
tcatacatccaggaagtggtgcagtacatcaagaggttagaagaggcccaaagtaaacgg
caggaaaaacttgtagagaaacacaaggagatacgtcagcagatcctggatgaaaagccc
aagctgcaggtggagctggagcaagaataccaagacaaattcaaaagactgccccttgaa
attttggaattcgtgcaggaagccatgaaagggaagatcagtgaagacagcaatcatggt
tctgcccctccctccctgtcctcagaccctggaaaagtgaaccacaagactccctccagt
gaggagctgggaggagacatcccaggaaaagaatttgatactcctctgtga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (6)   
   Pfam (6)   
All databases (14)   

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