KEGG   Spermophilus citellus (European ground squirrel): 308649088
Entry
308649088         CDS       T11988                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform 1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
scil  Spermophilus citellus (European ground squirrel)
Pathway
scil01522  Endocrine resistance
scil04010  MAPK signaling pathway
scil04015  Rap1 signaling pathway
scil04068  FoxO signaling pathway
scil04071  Sphingolipid signaling pathway
scil04114  Oocyte meiosis
scil04148  Efferocytosis
scil04218  Cellular senescence
scil04261  Adrenergic signaling in cardiomyocytes
scil04370  VEGF signaling pathway
scil04380  Osteoclast differentiation
scil04517  IgSF CAM signaling
scil04519  Cadherin signaling
scil04550  Signaling pathways regulating pluripotency of stem cells
scil04611  Platelet activation
scil04613  Neutrophil extracellular trap formation
scil04620  Toll-like receptor signaling pathway
scil04621  NOD-like receptor signaling pathway
scil04622  RIG-I-like receptor signaling pathway
scil04625  C-type lectin receptor signaling pathway
scil04657  IL-17 signaling pathway
scil04658  Th1 and Th2 cell differentiation
scil04659  Th17 cell differentiation
scil04660  T cell receptor signaling pathway
scil04664  Fc epsilon RI signaling pathway
scil04668  TNF signaling pathway
scil04670  Leukocyte transendothelial migration
scil04714  Thermogenesis
scil04722  Neurotrophin signaling pathway
scil04723  Retrograde endocannabinoid signaling
scil04728  Dopaminergic synapse
scil04750  Inflammatory mediator regulation of TRP channels
scil04912  GnRH signaling pathway
scil04914  Progesterone-mediated oocyte maturation
scil04917  Prolactin signaling pathway
scil04926  Relaxin signaling pathway
scil04932  Non-alcoholic fatty liver disease
scil04933  AGE-RAGE signaling pathway in diabetic complications
scil04935  Growth hormone synthesis, secretion and action
scil04936  Alcoholic liver disease
scil05014  Amyotrophic lateral sclerosis
scil05020  Prion disease
scil05022  Pathways of neurodegeneration - multiple diseases
scil05132  Salmonella infection
scil05133  Pertussis
scil05135  Yersinia infection
scil05140  Leishmaniasis
scil05142  Chagas disease
scil05145  Toxoplasmosis
scil05152  Tuberculosis
scil05161  Hepatitis B
scil05163  Human cytomegalovirus infection
scil05167  Kaposi sarcoma-associated herpesvirus infection
scil05169  Epstein-Barr virus infection
scil05170  Human immunodeficiency virus 1 infection
scil05171  Coronavirus disease
scil05205  Proteoglycans in cancer
scil05208  Chemical carcinogenesis - reactive oxygen species
scil05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
scil05415  Diabetic cardiomyopathy
scil05417  Lipid and atherosclerosis
scil05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:scil00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    308649088 (MAPK14)
   04015 Rap1 signaling pathway
    308649088 (MAPK14)
   04370 VEGF signaling pathway
    308649088 (MAPK14)
   04668 TNF signaling pathway
    308649088 (MAPK14)
   04068 FoxO signaling pathway
    308649088 (MAPK14)
   04071 Sphingolipid signaling pathway
    308649088 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    308649088 (MAPK14)
   04519 Cadherin signaling
    308649088 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    308649088 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    308649088 (MAPK14)
   04218 Cellular senescence
    308649088 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    308649088 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    308649088 (MAPK14)
   04613 Neutrophil extracellular trap formation
    308649088 (MAPK14)
   04620 Toll-like receptor signaling pathway
    308649088 (MAPK14)
   04621 NOD-like receptor signaling pathway
    308649088 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    308649088 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    308649088 (MAPK14)
   04660 T cell receptor signaling pathway
    308649088 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    308649088 (MAPK14)
   04659 Th17 cell differentiation
    308649088 (MAPK14)
   04657 IL-17 signaling pathway
    308649088 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    308649088 (MAPK14)
   04670 Leukocyte transendothelial migration
    308649088 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    308649088 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    308649088 (MAPK14)
   04917 Prolactin signaling pathway
    308649088 (MAPK14)
   04926 Relaxin signaling pathway
    308649088 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    308649088 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    308649088 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    308649088 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    308649088 (MAPK14)
   04722 Neurotrophin signaling pathway
    308649088 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    308649088 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    308649088 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    308649088 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    308649088 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    308649088 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    308649088 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    308649088 (MAPK14)
   05161 Hepatitis B
    308649088 (MAPK14)
   05171 Coronavirus disease
    308649088 (MAPK14)
   05163 Human cytomegalovirus infection
    308649088 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    308649088 (MAPK14)
   05169 Epstein-Barr virus infection
    308649088 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    308649088 (MAPK14)
   05135 Yersinia infection
    308649088 (MAPK14)
   05133 Pertussis
    308649088 (MAPK14)
   05152 Tuberculosis
    308649088 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    308649088 (MAPK14)
   05140 Leishmaniasis
    308649088 (MAPK14)
   05142 Chagas disease
    308649088 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    308649088 (MAPK14)
   05020 Prion disease
    308649088 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    308649088 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    308649088 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    308649088 (MAPK14)
   05415 Diabetic cardiomyopathy
    308649088 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    308649088 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    308649088 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    308649088 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    308649088 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:scil01001]
    308649088 (MAPK14)
Enzymes [BR:scil01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     308649088 (MAPK14)
Protein kinases [BR:scil01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   308649088 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 308649088
NCBI-ProteinID: XP_081150551
Position
5:52345064..52418620
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaagagaggcccacgttctatcggcaggagctgaacaagacaatctgggaggtg
cctgagcgttatcagaacctgtccccggtgggctccggtgcctatggctccgtgtgtgct
gcttttgacacaaaaactgggttacgtgtggcagtgaagaagctgtccagaccatttcag
tccatcattcatgccaaaaggacctacagagagctgcggttacttaaacacatgaaacat
gaaaatgtgattggtctgttggatgtgtttacacctgcaagatctctggaggaatttaat
gatgtgtatctggtgacccatctcatgggggcagatctgaacaacatagtaaagtgtcag
aagcttacggatgaccacgttcaattccttatctaccaaattctccgaggtctaaagtat
attcattcagctgatataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagattctggattttggactagctcgacatactgatgatgaaatgaca
ggctacgtggctacaaggtggtacagagctcctgagatcatgttgaactggatgcattac
aaccagacagtggatatatggtcagtgggatgcataatggcggagctgttaactggaaga
acattgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgagcttttgaagaaaatctcctcagagtctgcaagaaactatattcag
tctttgacccagatgcccaagatgaactttgcaaatgtatttattggtgccaatcccctg
gctgtcgacttgctggagaagatgcttgtattggactcagataagagaattactgcagcc
caagcccttgcacacgcctactttgctcagtatcatgatcctgatgatgaaccagtggcc
gatccttatgatcagtcttttgaaagcagggacctcctaatagatgagtggaaaagcctg
acctatgatgaagtcatcagctttgtgccgccgccccttgaccaagaagagatggagtcc
tga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (6)   
   Pfam (6)   
All databases (12)   

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