KEGG   Sorex fumeus (smoky shrew): 130039919
Entry
130039919         CDS       T10594                                 
Symbol
AP2A2
Name
(RefSeq) AP-2 complex subunit alpha-2 isoform X1
  KO
K11824  AP-2 complex subunit alpha
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum04142  Lysosome biogenesis
sfum04144  Endocytosis
sfum04721  Synaptic vesicle cycle
sfum04961  Endocrine and other factor-regulated calcium reabsorption
sfum05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    130039919 (AP2A2)
   04142 Lysosome biogenesis
    130039919 (AP2A2)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    130039919 (AP2A2)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    130039919 (AP2A2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    130039919 (AP2A2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sfum04131]
    130039919 (AP2A2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sfum04147]
    130039919 (AP2A2)
Membrane trafficking [BR:sfum04131]
 Endocytosis
  Clathrin-mediated endocytosis
   AP-2 complex
    130039919 (AP2A2)
Exosome [BR:sfum04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   130039919 (AP2A2)
SSDB
Motif
Pfam: Adaptin_N Alpha_adaptin_C Alpha_adaptinC2 Cnd1 HEAT_EF3_N RIX1 HEAT_GCN1 HEAT_2 HEAT_MROH2B_1st UTP20_N TOR1L1_N PDS5 DUF4003 SUV2_M
Other DBs
NCBI-GeneID: 130039919
NCBI-ProteinID: XP_055987874
Position
Unknown
AA seq 938 aa
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
KLLFIFLLGHDIDFGHMEAVNLLSSNRYSEKQIGYLFISVLVNSNSELIRLINNAIKNDL
ASRNPTFMGLALHCIANVGSREMGEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSP
DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFRTSVSLAVSRLSRIVTSA
STDLQDYTYYFVPAPWLSVKLLRLLQSYPPPEDPAARGRLTECLETILNKAQEPPKSKKV
QHSNAKNAVLFEAISLVIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCALASSE
FSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLEAADYCI
REEIVLKVAILAEKYAVDYAWYVDTILNLIRIAGDHVSEEVWFRVIQIVTNRDDVQGYAA
KTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLTQFHLLHSKFHLCSVPGRAL
LLSAYIKFVNLFPEVKATIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLE
EMPPFPERESSILAKLKRKKGRSSVGGLEASKRERGADLNGGPDPGQAVASATSTPSPSA
DLLGLGAPSAPAGPPPTSAGGLLVDVFSDSPSTAAPLAPGSEDNFARFVCKNNGVLFENQ
LLQVGLKSEFRQNLGRMLIFYGNKTSTQFFNFSPTLLCSDELQANLSLQTKPVDPTVDGG
AQVQQVVNIECISDFTEAPVLNVQFRYGGTLQNVSVKLPITLNKFFQPTEMASQDFFQRW
KQLSSPQQEVQNIFKAKHPMDTEITKAKIIGFGSALLEEVDPNPANFVGAGIIHTRTTQI
GCLLRLEPNLQAQVYRLTLRASKESVSQRLCELLAQQF
NT seq 2817 nt   +upstreamnt  +downstreamnt
atgccggccgtgtcgaagggggacgggatgcggggcctggcggtcttcatctcggacatc
cgcaactgtaaaagtaaagaggcagaaataaagagaataaacaaagagctggccaatatc
agatccaagtttaaaggagacaaggctctcgatggctacagcaagaaaaagtacgtgtgc
aagttgctcttcatcttccttctgggccacgacatcgacttcgggcacatggaggctgtc
aacctgctgagctccaacagatacagcgagaagcagattggctacctgttcatctccgtg
ctggtcaactccaactccgagctcatccgcctcatcaacaacgccatcaagaacgacctg
gccagccgcaaccccaccttcatgggtctggccctgcactgcatcgccaacgtgggcagc
cgcgagatgggcgaagcctttgctggggagatccccaaaattctggtagcgggggacacc
atggacagcgtgaagcagagcgcagccttgtgcctgctgcgcctgtaccgcacatctccg
gacctggtgcccatgggcgactggacctcccgcgtggtgcatctgctcaatgaccagcac
ctgggtgtggtgactgctgccaccagcctcatcaccaccctggcacagaagaaccccgag
gagttccgcacatctgtgtctttggctgtctccagactgagcaggatcgtcacgtcggcc
tccacggacctccaggactacacgtactactttgttccggcgccctggctctcggtgaag
ctgctgcggctgctgcagtcgtacccgcccccagaagaccccgcagcacgaggccgcctg
actgagtgcctggagacgatcctcaacaaggcccaggagccacccaagtccaagaaggtg
cagcactccaacgccaagaacgcggtgctcttcgaggccatcagcctcgtcatccaccat
gacagcgagcccaacctgctggtgcgtgcctgtaaccagctgggccagttcttgcagcac
cgtgagaccaacctgcgctacctggcgctggagagcatgtgtgcgctggccagctccgag
ttctcccatgaggctgtcaagacgcacattgagacggtcatcaatgccctcaagaccgag
cgggacgtgagcgtgcggcagcgggccgtggacctgctctacgccatgtgtgatcgcagc
aacgcgcagcagattgtggccgagatgctgagctacctggaagcagccgactactgcatc
cgggaggagatcgtgctgaaggtggccatcctggccgagaagtacgctgtggactacgcg
tggtacgtggacaccatcctcaacctcatccgcatcgccggcgaccacgtgagcgaggag
gtgtggttccgcgtgatccagatcgtcaccaaccgggacgacgtgcagggctacgccgcc
aagaccgtgttcgaggctctgcaggccccagcgtgccacgagaacctggtcaaagtgggg
ggctacatcctgggggagttcggcaacttgattgccggggacccgagatccagccccctg
actcagttccacctgctgcactccaagttccacctgtgcagtgtgcctggccgggcgctc
ctcctgtccgcctacatcaagttcgtcaatctcttcccggaggtcaaggccaccatccag
gacgtgttgcgcagtgacagccagctccgcaacgccgacgtggagctgcagcagcgtgcg
gtggagtacctgcgcctcagcactgtggccagcaccgacatcctggccacagtgctggag
gagatgccaccgttcccagagcgggaatcgtccatcctggccaagctgaagaggaagaag
ggccggagctccgtgggcggcctggaggcgagcaagcgggagcgtggcgccgacctcaac
gggggcccggaccccggccaggccgtggccagcgccacgtccacgccttccccgtctgca
gacctcctgggcctgggggcgccctctgcccctgcagggcccccccccacctcggcagga
gggctgctggtggacgtgttctcagactcaccgtccacggcagcacccctcgctcctggc
tccgaagacaactttgccaggttcgtctgcaagaacaacggcgtgttgtttgagaaccag
ctgctgcaggtcggcctgaagtctgagttccggcagaacttaggccgcatgctcatcttc
tacgggaacaagacctccacgcagttcttcaacttcagccccacgctgctgtgctccgac
gagctgcaggccaacctgagcctgcagaccaagcccgtggatcccaccgtggacgggggc
gcgcaggtgcagcaggtggtgaacattgagtgtatatccgacttcaccgaggcacccgtc
ctcaacgtccagttcaggtatggcggcaccttgcagaacgtgtccgttaagctgccgatc
acactcaacaagttcttccagcccacagaaatggcctctcaggatttctttcagcgttgg
aagcagctgagcagccctcagcaggaagtgcagaacatcttcaaggccaagcacccgatg
gacacggagatcaccaaagccaagattatcggatttggctctgcactccttgaagaggtc
gaccccaatcctgctaattttgtgggagctgggatcatccacaccagaaccactcagatt
ggctgcctgctgcgtctggagcccaatctgcaagcccaggtttaccgcctcacgctgcgt
gccagcaaggagagcgtctcccagcggctgtgcgagctgttggcccagcagttctaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (14)   
   Pfam (14)   
All databases (20)   

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