KEGG   Sardina pilchardus (sardine): 134068058
Entry
134068058         CDS       T10667                                 
Symbol
plcb4a
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
spil  Sardina pilchardus (sardine)
Pathway
spil00562  Inositol phosphate metabolism
spil01100  Metabolic pathways
spil04020  Calcium signaling pathway
spil04070  Phosphatidylinositol signaling system
spil04081  Hormone signaling
spil04082  Neuroactive ligand signaling
spil04261  Adrenergic signaling in cardiomyocytes
spil04270  Vascular smooth muscle contraction
spil04310  Wnt signaling pathway
spil04371  Apelin signaling pathway
spil04540  Gap junction
spil04621  NOD-like receptor signaling pathway
spil04912  GnRH signaling pathway
spil04916  Melanogenesis
Module
spil_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:spil00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    134068058 (plcb4a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    134068058 (plcb4a)
   04371 Apelin signaling pathway
    134068058 (plcb4a)
   04020 Calcium signaling pathway
    134068058 (plcb4a)
   04070 Phosphatidylinositol signaling system
    134068058 (plcb4a)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    134068058 (plcb4a)
   04081 Hormone signaling
    134068058 (plcb4a)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    134068058 (plcb4a)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    134068058 (plcb4a)
  09152 Endocrine system
   04912 GnRH signaling pathway
    134068058 (plcb4a)
   04916 Melanogenesis
    134068058 (plcb4a)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    134068058 (plcb4a)
   04270 Vascular smooth muscle contraction
    134068058 (plcb4a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:spil04131]
    134068058 (plcb4a)
Enzymes [BR:spil01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     134068058 (plcb4a)
Membrane trafficking [BR:spil04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    134068058 (plcb4a)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    134068058 (plcb4a)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2
Other DBs
NCBI-GeneID: 134068058
NCBI-ProteinID: XP_062379544
Position
20:complement(19055130..19088360)
AA seq 1205 aa
MARAYVFNWQKPLPSFMQEGAYFDRFEEDPFVFEPQCFFKVDEFGFFLTWKSEGKEGQLL
ESSLINSIRSTIPKDPKTLSSLEWMGRSENDLEGRTICICSGPDLVNLTFTFMVAQDASV
TKQWTAGLRSLIHNFRANNVCPMTCLRKHWMRLSFLTNVNGKIPVRSITRTFASGKTEKV
IFQALKDLGLPGGKNDEIDHSVFTFDKFYALTQKICPRTDIEELFKKINGGKSDYLNVDQ
LVCFLNERQRDPRLNEILFPFYDSKRAVQIVECYEPDDKLKRKGLMSSDGFCRYLMSDEN
APVYQDRLELYQDMEHPLAHYFISSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCVELDC
WDGKGEDQEPIITHGKAMCTDILFKDAIQAIKETAFVTSEYPVILSFENHCSKPQQYKLA
RYCEDIFGDLLLREPLEGFPMEPGCPLPSPRDLKRKILIKNRRSKPEAEQKELEEFKRHM
DAMDAADPFPTAEESSDGVDEAHPELRLGLPFCSADPGGAVEVEVGSGRETAEDEVEVFE
APDQENGKKVGDANVDVLDLINSYHYVAATTNVHPYLSSIVNYAQAVKFLGFEVAEENNI
HHNMSSFNETVCLGLLKTSAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVA
LNFQTPDLAMQLNQGKFEYNGSSGYLLKPDFMQRPDRMFDPFSETPVDGVIAATCSVQFI
SGQFLSDKKMGTYVEVDMYGLPTDTIRKEFRTKMVMNNGLNPVYNSEPFVFRKVILPDLA
VLRIAVYDDSNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCHIVLKTYVPDGF
GAIVDALSDPKRFLSITEKRVDQMKAMGIDECDIVDVPSASSRSDKRRKVSQVKARAGPS
PSQSGQLRHNASSTQLAAGPSSAPADTALLVHPVCVEDLKQMKTYLKLLKNQQRELSALK
KKHTKEQLEMQRAHGTQVDKIVTQHTKDKGTLEKQLEKAIKKAGEKSSSDLKMETDFKIQ
AITTEHKDKVKELLSQQAVEWSALTGGHGAESQALRDQHVLQQCELLKALLDSLQHQHHQ
QLQLIHNRQGKDIRAKQAKSSMESAKAISQDKSIKNKAERERRVRELNSCNTKKFLEERK
RLCMKQAKETEQLQRAQREQLDELDRCIEQLLRSHHSQHHSEAQRDAEEEGRQQASHSDA
TSSQT
NT seq 3618 nt   +upstreamnt  +downstreamnt
atggcacgggcatacgtgttcaactggcagaagcctcttcctagcttcatgcaggagggg
gcatactttgaccgatttgaagaggatccttttgtgtttgaaccgcagtgctttttcaaa
gtggatgagtttggtttcttccttacatggaaaagtgaaggaaaggaagggcagcttttg
gagagctctcttatcaacagcatccgcagcaccatacccaaggaccctaagactctgtcg
tcgctggagtggatgggaaggagtgagaatgacctggagggtcgcaccatctgcatatgc
agcggccctgacctggtcaatctcaccttcaccttcatggtggcccaggatgccagcgtt
accaagcagtggacggcgggcctgaggtcactgattcacaacttcagggccaacaacgtg
tgccccatgacctgcctgaggaaacattggatgaggctgtcatttcttacaaatgtgaat
ggcaagattccagtgagaagtattacaagaacctttgcctcaggcaaaactgaaaaagta
atcttccaagcactgaaggacttgggtcttcccggtggaaagaatgatgaaattgaccac
tcggtgtttacgtttgataagttttatgcactcacacaaaagatctgtcccagaactgac
attgaggaactcttcaagaagataaatggtggcaaaagtgattatttaaacgtagaccag
ttagtctgcttcttaaatgaacgtcagcgggacccgcggctcaacgagatccttttcccc
ttctatgactccaagcgggccgtgcagatcgtggagtgctacgagcccgacgacaagctg
aaaagaaaaggccttatgtcgagcgacggcttctgccgctacctgatgtcggacgagaac
gcccccgtctaccaggaccgcctggagctgtaccaggacatggagcatccgctggcccac
tacttcatcagctcctcgcacaacacatacctgacgggccgccagttcggggggaagtcc
tcggtggagatctaccggcaggtgctcctgtcaggctgcaggtgtgttgaacttgactgc
tgggatggcaagggtgaagaccaggagcctattatcacccacggcaaggccatgtgcaca
gacatcctcttcaaggatgctattcaggccatcaaggaaactgcctttgtgacatccgag
taccctgtgattctgtcctttgagaaccactgctccaagcctcagcagtacaagttggcc
cgatactgcgaggacatttttggggatctgttgctgcgggagccgctggaaggctttcca
atggagccgggctgccccctgccctctccccgcgacctcaagaggaaaatcctcatcaag
aaccgccggtccaagccagaggccgagcagaaagagctggaggagtttaagaggcacatg
gacgccatggacgctgcagatcccttccccaccgcggaggagagtagtgacggcgtggac
gaggcccacccagagctgcgtctggggctgccgttctgctccgctgacccgggcggcgcg
gtggaggtggaggtgggcagtggcagggaaacggcagaggatgaagtggaggtattcgaa
gcccctgatcaagagaatggcaaaaaggttggagacgcaaacgtggacgtcctggatctc
atcaacagctaccactacgtcgctgccacgaccaacgtccacccctacctctcatcgatc
gtcaattacgcccaagctgtgaagttcctgggctttgaagtagcggaggagaacaacatc
catcacaacatgtcctcgttcaacgaaacggtctgcctgggactgctgaagacgagtgcc
atcgagtttgtgaactacaacaagcggcagatgagccggatctatcccaaagggggccgg
gtggactccagtaattacatgcctcagatcttctggaatgccggctgccagatggtggct
ctgaacttccagaccccagatctggctatgcagctcaaccagggcaagtttgagtacaac
ggctcgtccgggtacctgctgaagcccgacttcatgcagcggcccgatcgcatgttcgat
ccgttctccgagaccccggtggacggcgtgatagccgccacgtgcagcgttcagtttatc
tccggtcagtttttgtcggacaaaaagatgggcacgtacgtggaggtggacatgtacggg
ctgcccacggacaccatcaggaaagagttccgcaccaagatggtgatgaataacggcctc
aaccccgtgtacaactccgagccctttgtgttccgaaaggtgatcctgccagacctggcg
gtgctgagaatagctgtgtatgatgacagcaataagctgattggccagaggatcctcccc
ctggacgggttgcaggcgggctaccgccacatctcgctgagaaacgagggcaacaagccg
ctctcgctgcccaccgtcttctgccacatcgtgctcaaaacatatgtgcccgacggcttc
ggggccatcgtggatgcattgtctgatcccaagaggttcttatccatcacggagaagaga
gtggaccagatgaaggccatgggcatcgacgagtgtgacatcgtggacgtgccgagcgcc
agctccaggagcgataagaggcggaaggtgagccaggtgaaggccagagccggcccgagc
ccgagccagagcggccagctccgccacaacgcctcgtccactcagctcgccgccggaccc
tcctccgcgccggccgacacagctctgctggtgcatccagtgtgcgtggaggacttgaag
cagatgaagacctacctcaaacttttgaagaaccagcagcgtgagctcagtgccttaaag
aagaaacacaccaaggagcagctggagatgcagagggcccacggcacccaagtggacaaa
atcgtgactcagcacaccaaagacaagggcactctggagaaacagctggagaaagcaatt
aagaaagcaggcgagaagagcagctccgatctgaagatggagacagactttaaaatccag
gccataaccacggaacacaaagacaaggtgaaggagctgctgtcccagcaggcggtggag
tggtcagcgctgaccggcggccacggcgcggagagccaggcgctgcgcgaccagcacgtg
ctgcagcagtgtgagctcctcaaggcgctgctcgactccctccagcaccagcaccaccag
cagctgcagctcatccacaaccggcagggcaaagacatccgcgccaagcaagccaagtcc
tccatggagagcgccaaagccatcagtcaagataaaagcatcaaaaataaggcggagaga
gaacggcgggtgcgggagctgaacagctgcaacacaaagaagttcttggaggagagaaaa
aggctgtgcatgaagcaggccaaggagacggagcagctgcagagggcccagcgagagcag
ctggacgagctggacaggtgcatcgagcagctgctgcgatcacatcactcccagcatcac
agtgaagctcagagagatgcagaggaagagggaaggcaacaggcgagccacagtgatgca
acaagcagtcaaacgtaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (11)   

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