KEGG   Tachyglossus aculeatus (Australian echidna): 119937152
Entry
119937152         CDS       T10703                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
tacu  Tachyglossus aculeatus (Australian echidna)
Pathway
tacu01522  Endocrine resistance
tacu04010  MAPK signaling pathway
tacu04015  Rap1 signaling pathway
tacu04068  FoxO signaling pathway
tacu04071  Sphingolipid signaling pathway
tacu04114  Oocyte meiosis
tacu04148  Efferocytosis
tacu04218  Cellular senescence
tacu04261  Adrenergic signaling in cardiomyocytes
tacu04370  VEGF signaling pathway
tacu04380  Osteoclast differentiation
tacu04517  IgSF CAM signaling
tacu04519  Cadherin signaling
tacu04550  Signaling pathways regulating pluripotency of stem cells
tacu04611  Platelet activation
tacu04613  Neutrophil extracellular trap formation
tacu04620  Toll-like receptor signaling pathway
tacu04621  NOD-like receptor signaling pathway
tacu04622  RIG-I-like receptor signaling pathway
tacu04625  C-type lectin receptor signaling pathway
tacu04657  IL-17 signaling pathway
tacu04658  Th1 and Th2 cell differentiation
tacu04659  Th17 cell differentiation
tacu04660  T cell receptor signaling pathway
tacu04664  Fc epsilon RI signaling pathway
tacu04668  TNF signaling pathway
tacu04670  Leukocyte transendothelial migration
tacu04714  Thermogenesis
tacu04722  Neurotrophin signaling pathway
tacu04723  Retrograde endocannabinoid signaling
tacu04728  Dopaminergic synapse
tacu04750  Inflammatory mediator regulation of TRP channels
tacu04912  GnRH signaling pathway
tacu04914  Progesterone-mediated oocyte maturation
tacu04917  Prolactin signaling pathway
tacu04926  Relaxin signaling pathway
tacu04932  Non-alcoholic fatty liver disease
tacu04933  AGE-RAGE signaling pathway in diabetic complications
tacu04935  Growth hormone synthesis, secretion and action
tacu04936  Alcoholic liver disease
tacu05014  Amyotrophic lateral sclerosis
tacu05020  Prion disease
tacu05022  Pathways of neurodegeneration - multiple diseases
tacu05132  Salmonella infection
tacu05133  Pertussis
tacu05135  Yersinia infection
tacu05140  Leishmaniasis
tacu05142  Chagas disease
tacu05145  Toxoplasmosis
tacu05152  Tuberculosis
tacu05161  Hepatitis B
tacu05163  Human cytomegalovirus infection
tacu05167  Kaposi sarcoma-associated herpesvirus infection
tacu05169  Epstein-Barr virus infection
tacu05170  Human immunodeficiency virus 1 infection
tacu05171  Coronavirus disease
tacu05205  Proteoglycans in cancer
tacu05208  Chemical carcinogenesis - reactive oxygen species
tacu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tacu05415  Diabetic cardiomyopathy
tacu05417  Lipid and atherosclerosis
tacu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119937152 (MAPK12)
   04015 Rap1 signaling pathway
    119937152 (MAPK12)
   04370 VEGF signaling pathway
    119937152 (MAPK12)
   04668 TNF signaling pathway
    119937152 (MAPK12)
   04068 FoxO signaling pathway
    119937152 (MAPK12)
   04071 Sphingolipid signaling pathway
    119937152 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    119937152 (MAPK12)
   04519 Cadherin signaling
    119937152 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    119937152 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    119937152 (MAPK12)
   04218 Cellular senescence
    119937152 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    119937152 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    119937152 (MAPK12)
   04613 Neutrophil extracellular trap formation
    119937152 (MAPK12)
   04620 Toll-like receptor signaling pathway
    119937152 (MAPK12)
   04621 NOD-like receptor signaling pathway
    119937152 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    119937152 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    119937152 (MAPK12)
   04660 T cell receptor signaling pathway
    119937152 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    119937152 (MAPK12)
   04659 Th17 cell differentiation
    119937152 (MAPK12)
   04657 IL-17 signaling pathway
    119937152 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    119937152 (MAPK12)
   04670 Leukocyte transendothelial migration
    119937152 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    119937152 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    119937152 (MAPK12)
   04917 Prolactin signaling pathway
    119937152 (MAPK12)
   04926 Relaxin signaling pathway
    119937152 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    119937152 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    119937152 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    119937152 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    119937152 (MAPK12)
   04722 Neurotrophin signaling pathway
    119937152 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    119937152 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    119937152 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    119937152 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    119937152 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    119937152 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    119937152 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    119937152 (MAPK12)
   05161 Hepatitis B
    119937152 (MAPK12)
   05171 Coronavirus disease
    119937152 (MAPK12)
   05163 Human cytomegalovirus infection
    119937152 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119937152 (MAPK12)
   05169 Epstein-Barr virus infection
    119937152 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    119937152 (MAPK12)
   05135 Yersinia infection
    119937152 (MAPK12)
   05133 Pertussis
    119937152 (MAPK12)
   05152 Tuberculosis
    119937152 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    119937152 (MAPK12)
   05140 Leishmaniasis
    119937152 (MAPK12)
   05142 Chagas disease
    119937152 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    119937152 (MAPK12)
   05020 Prion disease
    119937152 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    119937152 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119937152 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    119937152 (MAPK12)
   05415 Diabetic cardiomyopathy
    119937152 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    119937152 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    119937152 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    119937152 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    119937152 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tacu01001]
    119937152 (MAPK12)
Enzymes [BR:tacu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     119937152 (MAPK12)
Protein kinases [BR:tacu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   119937152 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like Haspin_kinase
Other DBs
NCBI-GeneID: 119937152
NCBI-ProteinID: XP_038612720
Position
14:54255917..54285021
AA seq 364 aa
MSERQPPQRGFSRQEVTRTLWEVRDLYRDLQPLGSGAYGAVCSAIDSRTGTKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDDTLDGFNDFYLVMPFMGTDLGKVM
KHEKLSEDRIQFLVYQMLKGLKYIHDAGIIHRDLKPGNLAVNEDCELKILDFGLARQTDS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLTEIMK
VTGTPPPEFVQKLQSQDAKNYMKTVPELEKKDFASILKDANPLAVNLLEQMLVLDAEKRV
TAAEAMGHPYFESVHDSEEEPQAEPYDDSFDNVDRSLDEWKRITYKEVLSFRPPPLFTPK
ESAL
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcggagcggcagccccctcagcgcggcttttcccggcaggaggtgacccgcacgctg
tgggaagtccgggacctctaccgggacctgcagccgctgggctccggggcctacggcgcc
gtctgctccgccatcgacagcaggaccggcaccaaggtggccatcaagaagctttaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgggagctgaggctgctgaagcac
atgcgacacgaaaacgtcatcggtctgctggacgtgttcacccccgatgacaccctggac
ggcttcaacgacttctacctggtgatgcccttcatgggtaccgacttgggcaaggtcatg
aagcacgagaagctctctgaggatcggatccagttcctggtctaccagatgctcaagggt
ctcaagtacatccacgacgccgggatcatccaccgggatctgaagcctgggaatctggct
gtgaatgaagactgtgagttgaagattctggacttcggcctggccaggcagacagacagt
gagatgaccggctatgtggtcacccgctggtaccgagcccctgaggtcatcctcaactgg
atgcactacactcagacagtggatatctggtccgtgggctgcatcatggccgagatgatc
actggcaagatcctcttcaaaggcaatgaccacctggaccagctgacggagatcatgaag
gtgacggggacgccgccgcccgaattcgtccagaagctgcagagtcaggacgccaaaaac
tacatgaaaactgttccggaattggagaagaaggattttgcctccatcctgaaggatgca
aaccctctggccgtgaacttgctggagcagatgctggtgctggacgcggagaagagggtg
accgccgccgaggccatgggccacccctactttgagtccgtccacgactcggaggaggag
ccccaggccgagccgtacgatgattccttcgacaacgtggaccggtcgctggacgagtgg
aagaggatcacttacaaggaggtcctgagcttcaggccgcccccactattcacgccaaag
gaatcagcgctatga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (11)   

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