KEGG   Tachyglossus aculeatus (Australian echidna): 119948753
Entry
119948753         CDS       T10703                                 
Symbol
APC
Name
(RefSeq) LOW QUALITY PROTEIN: adenomatous polyposis coli protein
  KO
K02085  adenomatosis polyposis coli protein
Organism
tacu  Tachyglossus aculeatus (Australian echidna)
Pathway
tacu04310  Wnt signaling pathway
tacu04390  Hippo signaling pathway
tacu04519  Cadherin signaling
tacu04550  Signaling pathways regulating pluripotency of stem cells
tacu04810  Regulation of actin cytoskeleton
tacu04934  Cushing syndrome
tacu05010  Alzheimer disease
tacu05022  Pathways of neurodegeneration - multiple diseases
tacu05165  Human papillomavirus infection
tacu05200  Pathways in cancer
tacu05206  MicroRNAs in cancer
tacu05210  Colorectal cancer
tacu05213  Endometrial cancer
tacu05217  Basal cell carcinoma
tacu05224  Breast cancer
tacu05225  Hepatocellular carcinoma
tacu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:tacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    119948753 (APC)
   04390 Hippo signaling pathway
    119948753 (APC)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    119948753 (APC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    119948753 (APC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    119948753 (APC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119948753 (APC)
   05206 MicroRNAs in cancer
    119948753 (APC)
  09162 Cancer: specific types
   05210 Colorectal cancer
    119948753 (APC)
   05225 Hepatocellular carcinoma
    119948753 (APC)
   05226 Gastric cancer
    119948753 (APC)
   05217 Basal cell carcinoma
    119948753 (APC)
   05213 Endometrial cancer
    119948753 (APC)
   05224 Breast cancer
    119948753 (APC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    119948753 (APC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    119948753 (APC)
   05022 Pathways of neurodegeneration - multiple diseases
    119948753 (APC)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    119948753 (APC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tacu01009]
    119948753 (APC)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:tacu03036]
    119948753 (APC)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:tacu04812]
    119948753 (APC)
Protein phosphatases and associated proteins [BR:tacu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     119948753 (APC)
Chromosome and associated proteins [BR:tacu03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    119948753 (APC)
Cytoskeleton proteins [BR:tacu04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     119948753 (APC)
SSDB
Motif
Pfam: Arm_APC_u3 APC_basic EB1_binding APC_r APC_u5 APC_u14 APC_rep APC_u9 APC_u15 APC_N_CC SAMP Arm APC_u13 APC_15aa Suppressor_APC ARM_ARMC5 ZER1-like_2nd Sec7-like_HUS
Other DBs
NCBI-GeneID: 119948753
NCBI-ProteinID: XP_038626179
Position
X3:11995139..12113031
AA seq 2847 aa
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
ASSGQIDLLERLKELNLDSSNFPGVKLRPKMSMRSYGSREGSVSSRSGECSPVPMGSFPR
RGFVNGSRESTGYLEELEKERSLLLAELEKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
QTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQLRVARIQQIEKDILRIRQLLQSQAA
EAERTPQSKHDAGSHEAERQNEGQGTAEISMATPGSGQGSTARMDHETASVMSSSSTYSV
PRRLTSHLGTKVTEDYKPQVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGC
LPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQ
IRAYCETCWEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGL
QAIAELLQVDCEMYGLTHDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQ
LKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSAL
WNLSAHCTENKAEICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDH
RQILRESSCLQTLLQHLKSHSLTIVSNACGTLWNLSARNAKDQEALWDMGAVSMLKNLIH
SKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSET
FDNIDNLSPKASHRNKQRHKQNLYSEYGFDSNRHDESRSESFTTGNVTVLSPYLNATVLP
VPGSSSSARGGLESSRSEKDRSLDRERGIGLGTYHPAPENPGNSSKRIGMQISTTAAQIA
KVMEEVSSIHVTQDDRSSGPTAEMHCMADERTALRRASTAHPHSSTFNFPKSENANRTCP
VPYPKMEYERASNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKI
HSANHMDDNDGDLDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHMIEDEMKQNEQRQS
RGPSTTYPGYGESSDDKHIKFQSHFGQQECVSPYRSRGANNAEPNRVGSGHGMNQKVNPS
LCQEDDYDDDDKPTNYSERYSEEEQHEEDRPTNYSIKYNEETHHTDQPIDYSLKYSSDGP
PSSQKPSFSFSKSSSAQSAKAEHISTSNGNVSTSSACAKRQSQLHPGSTPGRGGQTQKAA
SCKAPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGRDQVTRSADPASTLQITEL
KENAGAGSTEDAASEVPSASQLMRTKSGRLQTSNVSPSDSSRHKAVEFSSGAKSPSKSGA
QTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDS
PGQTMPPSRSKTPPPPQVVQAKRDAAKSKGPHADKREPGPRLAAVSAAVQRVQVLPDADT
LMHFATESTPDGFSCSSSLSALSLDEPYIQKDVELRIMPPVQENDHGNETDAEQPGEPTE
KQEKTAEKPTESEKDILDDSDDDDIDILEECIISAMPTKSSRKAKKPAQAASKIPPPVAR
KPSQLPVYKLLPSQSRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPN
ELVAIENIGTGAQPAGFEKRDTIPTEGRSTEDIPRGKNSASTTPVLDDSIAEEGDILAEC
INSAMPKGKSHKPFRVKKILNQAQQASAASSGSSKSQPEGERKKPTSPVKPMPQSIEYRA
RVKKNADSKNNFNTERSYADHKEAKKQNLKNHSRDFNDKLPNNEDRVRGSFAFDSPHHYT
PIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKETKEADTNASSHPEPSTNRTQV
CPKLPASRGQPKTLLQKPATFSQPSKDIPDRGAASDEKMQNFAIENTPVCFSCNSSLSSL
SDIDQENNNKDSEPIKPLDPPETQIESSRPQASGYAPKSFHVEDTPVCFSRNSSLSSLSI
DSEDDLLQECISSAMPKKKKPSRLKGDNEKNSSRNLGGVLAEDLTLDLRDIQRPDSEHGF
SPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTP
DQEEKPFTSNKGPRILKPGEKSTLESKKVESENKGIKGGKKVYKSLITGKVRSNSELSSQ
LKQPLPTNMPSISRGRTMIHIPGVRNSSSSTSPVAKKAPPLKAPASKSPNEGQPATTSPR
GAKPTIKSEASPVNRQPSQAGGSSKGPSRSGSRDSTPSRPPQQPLSRPMQSPGRSSISPG
RNGISPPNKLSQLPRTSSPSTASTKSSGSGRMAYTSPGRQMSQQNLAKPTGLSKNPSSIP
RSESASKGLNQAASSSGPNKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTL
RRKLEESASFESLSPSSRPDSPTRSQAQTPVLSPSLPDTHPSVQAGGWRKLPPSLNPSVD
SGEGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSA
SSESSEKAKSEDEKQVSAPVGPKPAKENQAPAKGTWRKIKENEMAPAGNTPQAASSGAPN
GADSKTLVYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKAGSTSKE
AKESQGKQNAGNGNAPVRSAGLENRLNSFIQLDSPDKKGTEGKPAQSNPTPTPEMGESSV
PERTPFSSSSSSKHSSPSGAVAARVTPFNYNPSPRKSSADSSSARPSQIPTPVNNSTKKR
DSKTENPEPGGTQSPKRHSGSYLVTSV
NT seq 8544 nt   +upstreamnt  +downstreamnt
atggctgcagcttcatatgatcagttgttaaagcaagttgaagcactgaagatggagaac
tcaaatcttcgacaagagctagaagataattcaaatcaccttaccaaactggaaactgag
gcatctaatatgaaggaggtgcttaaacagctacaaggaagcattgaagatgaagcaatg
gcttcttcaggacagattgatttgttggagcgacttaaggaacttaacttggacagcagt
aacttccccggggtgaaacttcggccaaagatgtccatgcgctcctatggaagccgggaa
gggtctgtatcaagtcgttcaggagagtgcagtcctgttcctatgggttctttcccaaga
agagggtttgtcaacggaagcagagagagtactggatatttagaagaacttgagaaagag
agatcactcctgcttgctgaacttgagaaagaagagaaagaaaaggactggtattatgct
cagcttcagaacctcactaaaaggatagatagtcttcctttaacagaaaatttctccttg
caaacggacatgaccaggcggcagttggagtatgaagcaagacagatcagagctgcaatg
gaagaacagctaggtacttgccaggatatggaaaaacgggcacagctgagagtggctaga
attcagcaaatagaaaaggacatacttcgcatccgacagctcttacagtcccaagcagct
gaagcagagaggacaccccagagcaagcatgatgcaggttctcatgaagccgagaggcaa
aatgaaggtcaaggaacagccgagatcagcatggcaactcctggtagtggtcagggttcc
actgcacggatggaccacgagacagccagtgtcatgagctctagtagtacctattctgtc
cctcgaagactgacaagtcacctgggtaccaaggtaaccgaagattacaaaccacaggtg
gaaatggtgtattcattgttgtcaatgcttggtactcatgataaggatgacatgtcacga
accttgctagctatgtctagctcccaggacagctgcatatccatgcgacagtcgggatgt
ctccctcttctcatccagctcttacatggcaatgacaaagactctgtgttgttgggcaat
tctcgaggcagtaaggaggcccgggccagggccagcgcagcactccacaacatcattcac
tcccagcctgatgacaagcgaggccggcgcgaaatccgcgtccttcatctgttggaacag
atccgtgcttactgtgagacatgttgggaatggcaggaggcccacgaacaaggcatggac
caggacaaaaatccaatgccagcacccgttgagcatcagatctgcccagctgtgtgtgtt
ctaatgaagctttcgtttgatgaagagcacaggcatgcaatgaatgaacttgggggacta
caagccattgcagaattattgcaagtggactgtgaaatgtatgggcttactcatgaccat
tacagtgttactttaagacgatatgctggcatggctttgacaaacttaacttttggggat
gtggctaacaaggctactctgtgttctatgaaaggctgtatgagagctcttgtagcccaa
ttgaaatctgaaagtgaagatttacagcaggtcattgcaagtgttttgaggaatttatca
tggcgggctgatgtaaatagtaaaaagactttgcgtgaagttggaagtgtgaaagcactg
atggagtgtgctctggaagttaaaaaggaatccactctaaaaagtgtattgagtgccttg
tggaatttgtcagctcattgcactgagaataaagccgagatctgtgctgtggatggtgct
ctggcgtttctagttggcaccctaacataccggagccagacaaatactttagccatcatt
gaaagtggaggtgggatattgcggaatgtgtccagcttaatagccaccaacgaggaccac
aggcaaatcctgagagaaagcagctgcttgcagacgttattacagcacttgaaatctcat
agcttgacaatagttagtaatgcgtgtggaaccttgtggaatctttcagcaagaaatgct
aaagatcaagaagcattgtgggacatgggagccgttagcatgctcaagaatctcattcac
tcaaagcacaaaatgattgctatgggcagtgctgcagctttaagaaacttgatggcaaat
agacctgcaaaatacaaggatgccaatatcatgtctcccggttcaagcttgccatctctt
catgttagaaagcaaaaggcattggaagcagaattagatgctcagcatttatcagagact
tttgacaacattgataatttaagccccaaagcatctcatcgtaataagcagagacacaag
caaaacctatacagcgaatatggttttgactctaatcggcacgatgagagcagatctgag
agttttactaccggaaatgtgaccgtcctttcgccatatttaaatgccacggtcttgccc
gtgcctggctcctcttcctctgcgcgaggaggcttggaaagttctcgttctgagaaagac
aggagtttggacagagagcgaggaatcggactaggcacgtaccatccagccccagaaaat
cccggaaactcttccaagcgaataggaatgcagatctccaccactgctgcccagattgcc
aaagtcatggaagaagtatctagcattcatgtcacacaagatgacaggagttctggaccc
actgcagaaatgcattgcatggcggacgaaagaaccgcgctgagaagagcgtcaacagcc
cacccacattcgagcacgtttaactttcctaaatccgaaaatgccaacaggacatgtcct
gtgccgtaccccaaaatggagtatgagcgagcttcaaacgatagcttaaatagtgtcagc
agtagtgatggctatgggaaaagaggccagatgaaaccttccattgagtcgtattctgaa
gatgatgagagcaaattttgcagctatgggcagtacccagccgacttagctcataagata
catagtgcgaatcacatggacgataatgatggcgatctcgacacaccgatcaattacagc
ctgaagtattcagatgagcagttgaactcggggaggcaaagtccctcccagaatgagaga
tgggcgagaccaaagcacatgatagaagatgaaatgaagcaaaatgaacaaaggcagtca
aggggtccaagcacaacctatcctgggtatggcgaaagcagcgatgacaaacacataaag
ttccagtctcactttggacagcaagaatgcgtttccccttacagatccagaggagccaat
aatgcggagccgaatcgagtgggctctggtcatgggatgaaccagaaagtaaacccgtct
ctctgtcaggaggatgattacgatgatgacgataagccaaccaactacagtgaacgctac
tcagaggaagagcaacatgaggaagacaggccgaccaattatagcatcaagtataacgag
gagacgcatcacacagaccagccgatcgattatagtttaaaatactccagcgatggcccg
ccttcctcgcagaagccatccttctcgttctccaagagttcttcagcgcaaagcgccaaa
gcggaacacatctccacgagcaatggaaatgtttccacctcctcggcttgtgccaagagg
cagagccagctccaccccggttccacgccaggtagaggcggacagactcaaaaggcggct
tcctgcaaggctccctccatcaaccaagaaacaattcagacgtactgtgtggaagataca
ccgatatgcttttcgcggtgtagttctctgtcgtccttgtcatccgccgaagatgaaatt
gggcgtgaccaggtgacccgtagcgccgaccctgccagcacgttacagataacggagctg
aaagaaaacgccggagccgggtcaaccgaggatgccgcaagcgaagtcccatccgcctcc
cagcttatgcgaaccaaatccggccggctccagacttcgaatgtatcgccttctgattcg
tcgagacataaggccgttgaattttcctccggtgccaaatctccatcgaaaagtggggcg
caaaccccgaagagcccgcctgagcattacgtccaggagacgccactcatgttcagccgc
tgtacgtctgtcagttccctggatagttttgagagccgctcgattgcaagctctgttcag
agcgagccttgtagcggcatggttagtggcatcatcagccccagcgaccttccggacagc
cctgggcaaaccatgcccccaagtaggagcaagaccccgccacctccccaggtggtccag
gcgaaaagggatgctgctaaaagcaaagggccgcatgctgacaaaagagaacctgggccc
aggctggcagctgtgagtgctgcagttcagagagtccaggtattgcccgatgctgatact
ctgatgcattttgctacagagagcaccccagatgggttttcttgttcctccagcctaagc
gcgctgagcctcgatgaaccgtatatacaaaaggatgtggagttgaggataatgccccca
gtacaggaaaatgaccatggaaacgaaacagacgccgagcagccaggagagccaaccgaa
aagcaagagaagacggcggagaaacccaccgaatcagaaaaggacatattggacgactcg
gatgacgacgacatcgacatattggaagaatgtatcatttcggctatgccgacaaaatct
tcccgaaaagccaagaagcccgcacaggctgcttcgaaaatccctccacctgtggccagg
aagcccagtcagctgccagtgtacaaactccttccttcccagagtcgattacagcctcaa
aagcatgttagtttcacccccggagatgatatgccacgggtgtattgtgtagaaggcacc
ccgataaacttctccacagctacgtcgctgagtgacctcacaatagaatcccccccgaat
gagctggttgccatcgaaaacatcgggacgggggcccagccggccggatttgaaaagaga
gatactatccctacggaaggcaggagcacagaagatattccaagagggaagaactcagcc
tcaactactcccgtgttggatgacagcatagctgaagaaggagacatccttgcggaatgc
attaattccgccatgcccaaaggaaaaagtcacaagcctttccgggtgaaaaagatcttg
aatcaggctcaacaagcatcagcagcttcctcgggaagtagcaaaagtcagccggagggt
gagaggaagaagcctacctcgccagttaaacccatgcctcaaagtatcgaatacagggcc
cgagtgaagaaaaatgccgactccaaaaataactttaatacggagagatcttatgcggac
cacaaagaggcaaagaagcagaatctgaaaaatcactccagggacttcaacgataaactt
ccaaataatgaagaccgtgtaagaggaagctttgctttcgattccccgcatcactacaca
ccaatcgaagggactccatactgtttttcgcgaaatgactctttgagttccctggatttc
gatgatgatgacgttgacctgtctagggaaaaggcagagttacggaaaggaaaagaaacc
aaggaagcagacactaacgctagcagccatccggagccatctactaatagaacccaagtt
tgtccaaaactgccagcgagcaggggtcagcccaagactttgctgcaaaagccagccact
ttctctcagccatctaaagatatcccggatagaggagcggcttcagatgaaaaaatgcag
aactttgctattgaaaacacacctgtttgcttttcatgtaattcatctctgagttctctc
agtgacatcgaccaagaaaataacaacaaggacagcgaacccatcaaaccactggaccct
cctgagacacagatcgaatcgagtagacctcaagcgtcgggttacgcgcccaagtcgttt
cacgtcgaagataccccagtgtgtttttcgcgaaacagctccctaagttctcttagtata
gattctgaagatgacctcttgcaggaatgcatcagttccgcgatgccaaaaaagaaaaag
ccttctagacttaagggggataatgaaaagaatagttcccggaacctgggtggcgtatta
gctgaagatttgaccctcgatttgagagacatccaaaggccagattcagagcatggtttc
tctcctgattcggagaactttgactggaaagcgattcaggaaggtgcaaattccatcgta
agtagtctgcatcaagctgctgctgctgcttgtttatctagacaagcttcatctgactct
gattccatcctgtcactaaaatctgggatttctttgggctcaccatttcatctcacgccc
gaccaagaggagaaaccctttacaagtaataaaggcccacgaatactgaagcctggggaa
aaaagtacattagaaagtaaaaaagttgagtctgaaaacaaggggatcaaaggagggaaa
aaggtgtacaaaagcttgattactgggaaagtgcggtcaaattcagaactctcaagccag
ttgaagcagcccctgccaacaaatatgccgtccatctcgcgaggtcgaacaatgattcac
attccaggagttcgtaacagctcttcaagcacaagtccagttgccaaaaaggcccccccg
ctgaaggccccagcctccaaaagccccaacgaaggccagcccgccacaacttctccaaga
ggggccaagccaacgatcaaatcggaagccagcccggtgaaccggcagccgtcccaagcg
ggtgggtcaagtaaaggaccttccagatcagggtcaagagattctactccttctagaccg
cctcagcagccactgagtaggcccatgcagtctccggggcgaagctccatttctcccggg
agaaacggaataagtcctcccaacaagctgtctcaactgccccggacgtcatcccccagt
actgcttcaaccaagtcctcaggttcgggaagaatggcgtacacgtctccgggccggcag
atgagtcagcagaatcttgccaaaccaacaggcctgtccaagaaccctagcagtattccc
agaagtgagtctgcctccaaaggattaaaccaggcggccagcagcagtgggccgaataaa
aaggtagagctctccagaatgtcttcaaccaaatccagcgggagtgaatccgacagatcg
gagagacccgttctggtgcggcagtccactttcattaaagaagcccccagccccacgctg
aggagaaagttggaagaatctgcctcgtttgaatccctgtctccatcttcgcgaccggat
tcgcccacaagatcccaggcccagactccggtgttaagcccgtcccttcccgacacgcac
ccgtcggtccaggctgggggttggcgcaaactgcctccctctctcaaccccagtgtcgac
tctggtgagggaaggccagcgaagcgccatgatatcgctcgctcccactccgaaagcccg
tccaggctgccgatcaatcgatccggaacttggaagcgcgagcacagcaaacactcctcc
tcgctgcctcgcgtaagcacttggcgaagaactggaagctcttcctcgatcctctctgct
tcatcagaatccagcgagaaagccaaaagtgaagatgagaagcaggtgagtgctcctgtg
ggccccaaaccggctaaagaaaaccaagccccggcgaaaggaacgtggagaaaaatcaag
gagaacgagatggctcctgcaggtaatacgcctcaggccgcctcctcgggcgccccaaat
ggcgcggactcgaagactctagtttatcaaatggcccccgccgtctctaagacagaggac
gtgtgggtgaggatcgaggactgtcccatcaataaccctagatcaggaagatctcccacg
ggaaacactcccccggtgattgacagtgtttccgagaaggccggttcaaccagtaaagag
gcaaaagagagtcaggggaaacaaaatgcaggaaatggcaatgcaccagttcgctccgca
ggcttggaaaatcgcctgaattcgttcattcagctagatagcccggataaaaaggggact
gaaggcaagccggcccagagcaatccaacccccactccagagatgggggaaagttccgtc
cctgaacgtacgccattcagttccagcagctcgagcaagcacagttccccaagtggagcc
gttgctgcccgagtgacccctttcaattacaatccaagccctaggaagagcagcgcagac
agcagttcagcccggccatctcagatccccaccccagtcaataatagcacaaagaaacgg
gattcgaaaacggaaaacccagagcccggtggaactcaaagccctaaacgccattctgga
tcttacttggtaacttctgtttga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (18)   
   Pfam (18)   
All databases (22)   

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