KEGG   Trachypithecus francoisi (Francois's langur): 117064818
Entry
117064818         CDS       T07225                                 
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
tfn  Trachypithecus francoisi (Francois's langur)
Pathway
tfn04310  Wnt signaling pathway
tfn04390  Hippo signaling pathway
tfn04519  Cadherin signaling
tfn04550  Signaling pathways regulating pluripotency of stem cells
tfn04810  Regulation of actin cytoskeleton
tfn04934  Cushing syndrome
tfn05010  Alzheimer disease
tfn05022  Pathways of neurodegeneration - multiple diseases
tfn05165  Human papillomavirus infection
tfn05200  Pathways in cancer
tfn05206  MicroRNAs in cancer
tfn05210  Colorectal cancer
tfn05213  Endometrial cancer
tfn05217  Basal cell carcinoma
tfn05224  Breast cancer
tfn05225  Hepatocellular carcinoma
tfn05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:tfn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    117064818 (APC)
   04390 Hippo signaling pathway
    117064818 (APC)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    117064818 (APC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    117064818 (APC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    117064818 (APC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117064818 (APC)
   05206 MicroRNAs in cancer
    117064818 (APC)
  09162 Cancer: specific types
   05210 Colorectal cancer
    117064818 (APC)
   05225 Hepatocellular carcinoma
    117064818 (APC)
   05226 Gastric cancer
    117064818 (APC)
   05217 Basal cell carcinoma
    117064818 (APC)
   05213 Endometrial cancer
    117064818 (APC)
   05224 Breast cancer
    117064818 (APC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    117064818 (APC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    117064818 (APC)
   05022 Pathways of neurodegeneration - multiple diseases
    117064818 (APC)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    117064818 (APC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tfn01009]
    117064818 (APC)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:tfn03036]
    117064818 (APC)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:tfn04812]
    117064818 (APC)
Protein phosphatases and associated proteins [BR:tfn01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     117064818 (APC)
Chromosome and associated proteins [BR:tfn03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    117064818 (APC)
Cytoskeleton proteins [BR:tfn04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     117064818 (APC)
SSDB
Motif
Pfam: Arm_APC_u3 APC_basic EB1_binding APC_r APC_u5 APC_u14 APC_rep APC_u15 APC_u9 SAMP Arm APC_u13 APC_15aa Suppressor_APC ARM_ARMC5 ZER1-like_2nd Sec7-like_HUS SSNA1
Other DBs
NCBI-GeneID: 117064818
NCBI-ProteinID: XP_033034807
Position
Unknown
AA seq 2871 aa
MYASLGSGPVGALPVSVPPSTLRCWSTDGSRSCVRQETKSPGGARTSGNWASVWQEVLKQ
LQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGEC
SPVPMGSFPRRGFVNGSRESIGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRID
SLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILR
IRQLLQSQATEAERSSQNKHETGSHDAERQNEGQGVAEINMATSGNGQGSATRMDHETAS
VLSSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQS
GCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLL
EQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELG
RKATRGISSQELGQGLSGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGD
VANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKAL
MECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAII
ESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNP
KDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSL
HVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSD
NFNAGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGT
SSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHAHS
NTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDES
KFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARP
KHIIEDEIKQSEQRQSRSQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSET
NRVGSNHGINQNVSQSLCQEDVYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKHH
VDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSTKTEHISSSSENTSTPSSNAKRQNQLH
PSSAQSRSGQTQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCDQT
TQEADSANTLQIAEIKDKIGTRSTEDPVSEVPAVSQHTRTKSSRLQGSSLSSESTRHKAV
EFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSG
MVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKRETPKNKTPTAEKRESGPKQAAV
NAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQEND
NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK
KPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFS
TATSLSDLTIESPPNELAAGEGVRAGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPE
LDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMGQVQQASASSSATNKNQLDGKKKKP
TSPVKPIPQNTEYRTRIRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKDFNDKLPNNED
RVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEA
KVTSHTELTSNQQSASKTQAIAKHPINRGQLKPILQKQSTFPQSSKDIPDRGAATDEKLQ
NFAIENTPVCFSHNSSLSSLSDIDQENNNNKENEPIKETEPPDSQGEPSKPQASGYAPKS
FHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGI
LAEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSD
SDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGG
KKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGP
PLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSR
PAQQPLSRPVQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGR
QMSQQNLTKQTGLSKNASSIPRSESASKGLNQVNNGNGANKKIELSRMSSTKSSGSESDR
SERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDM
SLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPVKRHDIARSHSESPSRLPINRSGTWKREH
SKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGT
WRKIKENEISPTNSTSQTISSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRS
GRSPTGNTPPVIDSVSEKGNANKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPD
QKGTETKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRK
SSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV
NT seq 8616 nt   +upstreamnt  +downstreamnt
atgtacgcctccctgggctcgggtccggtcggtgctttgccggtttctgtaccaccctca
actctccggtgctggagcaccgacggcagcaggagctgcgtccggcaggagacgaaaagc
ccaggcggcgctcgtacttctgggaactgggcgagcgtctggcaggaagtacttaaacaa
ctacaaggaagtattgaagatgaagctatggcttcttctggacagattgatttattagag
cgtcttaaagagcttaacttagatagcagtaatttccctggagtaaaactacggtcaaaa
atgtccctccgttcttatggaagccgggaaggatctgtatcaagccgttctggagagtgc
agtcctgttcccatgggttcatttccaagaagagggtttgtaaatggaagcagagaaagt
attggatatttagaagaacttgagaaagagaggtcgttgcttcttgctgatcttgacaaa
gaagaaaaggaaaaagactggtattatgctcaacttcagaatctcactaaaagaatagat
agtcttcctttaactgaaaatttttccttacaaacagatatgaccagaagacagctggaa
tatgaagcgaggcaaatcagagttgcaatggaagaacaactaggtacctgccaggatatg
gaaaaacgagcacagcgaagaatagccagaattcagcaaatcgaaaaggacatacttcgt
atacgacagcttttacagtcccaagcaacagaagcagagaggtcgtctcagaacaagcat
gaaaccggctcacatgatgctgagcggcagaatgaaggtcaaggagtggcagaaatcaac
atggcaacttctggtaatggtcagggttcagctacacgaatggaccacgaaacagccagt
gttttgagttctagtagcacacactctgcacctcgaaggctgacaagtcatctgggaacc
aaggtggaaatggtgtattcattgttgtcaatgcttggtactcatgataaggatgatatg
tcgcgaactttgctagctatgtctagctcccaagacagctgtatatccatgcgacagtct
ggatgtcttcctctcctcatccagcttttacatggcaatgacaaagactctgtattgttg
ggaaattcccggggcagtaaagaggctcgggccagggccagtgcagcactccacaacatc
attcactcacagcctgatgacaagagaggcaggcgtgaaatccgagtccttcatcttttg
gaacagatacgcgcttactgtgaaacgtgttgggagtggcaggaagctcatgaacaaggc
atggaccaggacaaaaatccaatgccagctcctgttgaacatcagatctgtcctgctgtg
tgtgttctaatgaaactttcatttgatgaagagcatagacatgcaatgaatgaactaggt
aggaaggctacccggggcatttcatcacaggagctagggcaggggctttcagggggacta
caggccattgcagaattattgcaagtggactgtgaaatgtatgggcttactaatgaccac
tacagtattacactaagacgatatgctggaatggctttgacaaacttgacttttggagat
gtagccaacaaggctacgctatgctctatgaaaggctgcatgagagcacttgtggcccaa
ctaaaatctgaaagtgaagacttacagcaggttattgcaagtgttttgcggaatttgtct
tggcgagcagatgtaaatagtaaaaagacgttgcgggaagtcggaagtgtgaaagcattg
atggaatgtgctttagaagttaaaaaggaatcaaccctcaaaagcgtattgagtgcctta
tggaatttgtcagcacattgcactgagaataaagctgatatatgtgctgtagatggtgca
cttgcatttttggttggcactcttacttaccggagccagacaaacactttagccattatt
gaaagtggaggtgggatattacggaatgtgtccagcttgatagctacaaatgaggaccac
aggcaaattctaagagagaacaactgtctacagactttattacaacacttaaaatctcat
agtttgacaatagtcagtaatgcttgtggaactttgtggaatctctcagcaagaaatcct
aaagaccaggaagcattatgggacatgggggcagttagcatgctcaagaacctcattcat
tcaaagcacaaaatgattgctatgggaagtgctgcagctttaaggaatctcatggcaaat
aggcctgcgaagtacaaggatgccaatattatgtctcctggctcaagcttgccatctctt
catgttaggaaacaaaaagccctagaagcagaattagatgctcagcatttgtcagaaact
tttgacaatatagacaatttaagtcccaaggcatctcatcgtagtaagcaaagacacaag
caaagtctctatggtgattatgtttttgacaccaatcgacatgatgataataggtcagat
aattttaatgctggcaacatgactgtcctttcaccatatttgaatactacagtgttaccc
agctcctcttcatcaagaggaagcttagatagttctcgttctgaaaaagatagaagtttg
gagagagaacgaggaattggtctaggcaactaccatccagcaacagaaaatccaggaacc
tcttcaaagcgaggtttgcagatctccaccactgcagcccagattgccaaagtcatggaa
gaagtgtcagccattcatacctctcaggaagacagaagttctgggtctaccactgaatta
cattgtgtgacagatgagagaaatgcacttagaagaagctctgctgcccatgcacattca
aacacttacaatttcactaagtcagaaaattcaaataggacatgttctatgccttatgcc
aaattagaatacaagagatcttcgaatgatagtttaaatagtgtcagtagtagtgatggt
tatggtaaaagaggtcaaatgaaaccctcaattgaatcctattctgaagatgatgaaagt
aagttttgcagttatggtcaatacccagccgacctagcccataaaatacatagtgcaaat
catatggatgataatgatggagaactagatacaccaataaattatagtcttaaatattca
gatgagcagttgaactctggaaggcaaagtccttcacagaatgaaagatgggcaagaccc
aaacacataatagaagatgaaataaaacaaagtgagcaaagacaatcaaggagtcaaagt
acaacttatcctgtttatactgagagcactgatgataaacacctcaagttccaaccacat
tttggacagcaggaatgtgtttctccatacaggtcacggggagccaacggttcagaaaca
aatcgagtgggttctaatcatggaattaatcaaaatgtaagccagtctttgtgtcaagaa
gatgtctatgaagatgataagcctaccaattatagtgaacgttactctgaagaagaacag
catgaagaagaagagagaccaacaaattatagcataaaatacaatgaagagaaacatcat
gtggatcagcctattgattatagtttaaaatatgccacagatattccttcttcacagaaa
cagtcattttcattctcaaagagttcatctggacaaagcactaaaactgaacatatctct
tcaagcagtgagaatacgtccacaccttcatctaatgccaagaggcagaatcagctccat
ccaagttctgcacagagtagaagtggtcagactcaaaaggctgccacttgcaaagtttct
tctattaaccaagaaacaatacagacttattgtgtggaagatactccaatatgtttttca
agatgtagttcactatcatctttgtcatcagctgaagatgaaataggatgtgatcagacg
acacaggaagcagattctgctaataccctgcaaatagcagaaataaaagacaagattgga
actaggtcaactgaagaccctgtaagtgaagttccagcagtgtcgcagcacactagaacc
aaatccagcagactgcagggttctagtttatcttcagaatcaaccaggcacaaagctgtt
gaattttcttcaggagcaaaatctccctccaaaagtggtgctcagacacccaaaagtcca
cctgaacactatgttcaggagactccacttatgtttagcagatgtacttccgtcagttca
cttgatagttttgagagtcgttcgattgccagctccgttcagagtgaaccatgcagtgga
atggtaagtggcattataagccccagtgatcttccagatagccctggacaaaccatgcca
ccaagcagaagtaaaacccctccaccaccacctcaaacagctcaaaccaagcgagaaaca
cctaaaaataaaacacctactgccgaaaagagagagagtggacctaagcaagctgcagta
aatgctgcagttcagagggtccaggttcttccagatgctgatactttattacactttgcc
acagaaagtactccagatggattttcttgttcatctagcctgagtgctctgagcctcgat
gagccatttatacagaaagatgtggaattaagaataatgcctccagttcaggaaaatgac
aatgggaatgaaacagaatcagaacaacctaaagaatcaaatgaaaaccaagagaaagag
gcagaaaaaactattgattctgaaaaggacctattagatgattcagatgatgatgatatt
gaaatactagaagaatgtattatttctgccatgccaacaaagtcatcacgtaaagcaaaa
aagccagcccagactgcttcaaaattacctccacctgtggcaaggaaaccaagtcagctg
cctgtgtacaaacttctgccatcacaaaacaggttgcaaccccaaaagcatgttagtttt
acaccgggagatgatatgccacgagtgtattgtgtagaagggacacctataaacttttcc
acagctacatctctaagtgatctaacaatagaatcccctccaaatgagttagctgctgga
gaaggagttagagcaggggcacagtcaggtgaatttgaaaaacgagataccattcctaca
gaaggcagaagtacagatgaggctcaaggaggaaaaacctcatctgtaaccatacctgaa
ttggatgacaataaagcagaggaaggtgatattcttgcagaatgcattaattctgctatg
cccaaagggaaaagtcacaagcctttccgtgtgaaaaagataatgggccaggtccagcaa
gcatctgcgtcctcttctgcaaccaacaaaaatcagttagatggtaagaaaaagaaacca
acttcaccagtaaaacctataccacaaaatactgaatatcggacacgtataagaaaaaat
gcagactcaaaaaataatttaaatgctgagagagttttctcagacaacaaagattcaaag
aaacagaatttgaaaaataattccaaggacttcaacgataagctcccaaataatgaagat
agagtcagaggaagttttgcttttgattcacctcatcattacacacctattgaaggaact
ccttactgtttttcacgaaatgattctttgagttctctagattttgatgatgatgatgtt
gacctttccagggaaaaggctgaattaagaaaggcgaaagaaaataaggaatcagaagct
aaagttaccagccacacagaactaacctccaaccaacaatcagctagtaagacacaagct
attgcaaagcatccaataaatcgaggtcagcttaaacccatactgcagaagcaatccact
tttccccagtcatccaaagacataccagacaggggggcagcaactgatgaaaaattacag
aattttgctattgaaaatactccagtttgcttttctcataattcctctctgagttctctc
agtgacattgaccaagaaaacaacaacaataaagaaaatgaacctatcaaagagactgag
ccccctgattcacagggagaaccaagtaaacctcaagcatcaggctatgctccaaaatcg
tttcatgttgaagataccccagtttgtttttcaagaaacagttctctcagttctcttagt
attgactctgaagatgacctgttgcaggaatgtataagctccgcaatgccaaaaaagaaa
aagccttcaagacttaagggtgataatgaaaaacatagtcccagaaatatgggtggcata
ttagctgaagatctgacacttgatttgaaagatatacagagaccagattcagaacatggt
ttatcccctgattcagaaaattttgattggaaagctattcaggaaggtgcaaattccata
gtaagtagtttacatcaagctgctgctgctgcatgtttatctagacaagcttcatctgat
tcagattccatcctttccctgaaatcaggaatctctctgggatcaccatttcatcttaca
cctgatcaagaagaaaaaccctttacaagtaataaaggcccacgaattctaaaaccaggg
gagaaaagtacattggaaactaaaaagatagaatctgaaagtaaaggaatcaaaggagga
aaaaaagtttataaaagtttgattactggaaaagttcgatctaattcagaaatttcaggc
caaatgaagcagccccttcaagcaaacatgccttcaatctctcgaggcaggacaatgatt
catattccaggagttcgaaatagctcctcaagtacaagtcctgtttctaaaaaaggccca
ccccttaagactccagcctccaaaagccctagtgaaggtcaaacggccaccacttctcct
agaggagccaagccatctgtgaaatcagaattaagccctgttgccaggcagacatctcaa
ataggtgggtcaagtaaagcaccttctagatcaggatctagagattcgaccccttcaaga
cctgcccagcaaccgttaagtagacctgtacagtctcctggccgaaactcaatttcccct
ggtagaaatggaataagtcctcctaacaaattatctcagcttccaaggacatcatctcct
agtactgcttcaactaagtcctcaggttctggaaaaatgtcgtatacatctccaggcaga
cagatgagccaacagaaccttaccaaacaaacaggtttatccaagaacgccagtagtatt
ccaagaagtgagtctgcctccaaagggctaaatcaggtgaataatggtaatggagccaat
aaaaagatagaactttctagaatgtcttcaactaaatcaagtggaagtgaatctgataga
tcagaaagacctgtattagtacgccagtcaactttcatcaaagaagctccaagcccaacc
ttaagaagaaaattggaggaatctgcttcatttgaatctctttctccatcgtctagaccg
gcttctcccactaggtcccaggcacaaactccagttttaagtccttcccttcctgatatg
tctctatccacacattcatctgttcaggctggtggatggcgaaaactaccccctaatctc
agtcccactatagagtataatgatggaagaccagtaaagcgccatgatattgcacggtct
cattctgaaagtccttctagacttccgatcaataggtcaggaacctggaaacgtgagcac
agcaaacattcatcatcccttcctcgagtaagcacttggagaagaactggaagttcatct
tcaattctttctgcttcatcagaatccagtgaaaaagcaaaaagtgaggatgaaaaacat
gtgaactctatttcaggaaccaaacaaagtaaagaaaaccaagtatctgcaaaaggaaca
tggagaaaaataaaagaaaatgaaatttctcccacaaatagtacttctcagaccatttcc
tcaggtgctacaaatggtgctgaatcaaagactctaatttatcaaatggcacctgctgtt
tctaaaacagaggatgtttgggtaagaattgaggactgtcccattaacaatcctagatct
ggaagatctcccacaggtaatactcccccggtgattgacagtgtttcagaaaagggaaat
gcaaacaaagattcaaaagataatcaggcaaaacaaaatgtgggtaatggcagtgttccc
atgcgtaccgtgggtttggaaaatcgcctgaactcctttattcaggtagatgcccctgac
cagaaaggaactgagacaaaaccaggacaaaataatcctgtccctgtatcagagactaat
gaaagttctatagtggagcgtaccccattcagttctagcagctcaagcaaacacagttca
cctagtgggactgttgctgccagagtgactccttttaattacaacccaagccctaggaaa
agcagcgcagatagcacttcagctcggccgtctcagatcccaactccagtgaataacaac
acaaagaagcgagattcaaaaactgacagcacagaatccagtggaacccaaagtcctaag
cgtcattctgggtcttaccttgtgacatccgtttaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (10)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (18)   
   Pfam (18)   
All databases (40)   

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