KEGG   Trachypithecus francoisi (Francois's langur): 117096273
Entry
117096273         CDS       T07225                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
tfn  Trachypithecus francoisi (Francois's langur)
Pathway
tfn01522  Endocrine resistance
tfn04010  MAPK signaling pathway
tfn04015  Rap1 signaling pathway
tfn04068  FoxO signaling pathway
tfn04071  Sphingolipid signaling pathway
tfn04114  Oocyte meiosis
tfn04148  Efferocytosis
tfn04218  Cellular senescence
tfn04261  Adrenergic signaling in cardiomyocytes
tfn04370  VEGF signaling pathway
tfn04380  Osteoclast differentiation
tfn04517  IgSF CAM signaling
tfn04519  Cadherin signaling
tfn04550  Signaling pathways regulating pluripotency of stem cells
tfn04611  Platelet activation
tfn04613  Neutrophil extracellular trap formation
tfn04620  Toll-like receptor signaling pathway
tfn04621  NOD-like receptor signaling pathway
tfn04622  RIG-I-like receptor signaling pathway
tfn04625  C-type lectin receptor signaling pathway
tfn04657  IL-17 signaling pathway
tfn04658  Th1 and Th2 cell differentiation
tfn04659  Th17 cell differentiation
tfn04660  T cell receptor signaling pathway
tfn04664  Fc epsilon RI signaling pathway
tfn04668  TNF signaling pathway
tfn04670  Leukocyte transendothelial migration
tfn04714  Thermogenesis
tfn04722  Neurotrophin signaling pathway
tfn04723  Retrograde endocannabinoid signaling
tfn04728  Dopaminergic synapse
tfn04750  Inflammatory mediator regulation of TRP channels
tfn04912  GnRH signaling pathway
tfn04914  Progesterone-mediated oocyte maturation
tfn04917  Prolactin signaling pathway
tfn04926  Relaxin signaling pathway
tfn04932  Non-alcoholic fatty liver disease
tfn04933  AGE-RAGE signaling pathway in diabetic complications
tfn04935  Growth hormone synthesis, secretion and action
tfn04936  Alcoholic liver disease
tfn05014  Amyotrophic lateral sclerosis
tfn05020  Prion disease
tfn05022  Pathways of neurodegeneration - multiple diseases
tfn05132  Salmonella infection
tfn05133  Pertussis
tfn05135  Yersinia infection
tfn05140  Leishmaniasis
tfn05142  Chagas disease
tfn05145  Toxoplasmosis
tfn05152  Tuberculosis
tfn05161  Hepatitis B
tfn05163  Human cytomegalovirus infection
tfn05167  Kaposi sarcoma-associated herpesvirus infection
tfn05169  Epstein-Barr virus infection
tfn05170  Human immunodeficiency virus 1 infection
tfn05171  Coronavirus disease
tfn05205  Proteoglycans in cancer
tfn05208  Chemical carcinogenesis - reactive oxygen species
tfn05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tfn05415  Diabetic cardiomyopathy
tfn05417  Lipid and atherosclerosis
tfn05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tfn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117096273 (MAPK12)
   04015 Rap1 signaling pathway
    117096273 (MAPK12)
   04370 VEGF signaling pathway
    117096273 (MAPK12)
   04668 TNF signaling pathway
    117096273 (MAPK12)
   04068 FoxO signaling pathway
    117096273 (MAPK12)
   04071 Sphingolipid signaling pathway
    117096273 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    117096273 (MAPK12)
   04519 Cadherin signaling
    117096273 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    117096273 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    117096273 (MAPK12)
   04218 Cellular senescence
    117096273 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    117096273 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    117096273 (MAPK12)
   04613 Neutrophil extracellular trap formation
    117096273 (MAPK12)
   04620 Toll-like receptor signaling pathway
    117096273 (MAPK12)
   04621 NOD-like receptor signaling pathway
    117096273 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    117096273 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    117096273 (MAPK12)
   04660 T cell receptor signaling pathway
    117096273 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    117096273 (MAPK12)
   04659 Th17 cell differentiation
    117096273 (MAPK12)
   04657 IL-17 signaling pathway
    117096273 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    117096273 (MAPK12)
   04670 Leukocyte transendothelial migration
    117096273 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    117096273 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    117096273 (MAPK12)
   04917 Prolactin signaling pathway
    117096273 (MAPK12)
   04926 Relaxin signaling pathway
    117096273 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    117096273 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    117096273 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    117096273 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    117096273 (MAPK12)
   04722 Neurotrophin signaling pathway
    117096273 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    117096273 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    117096273 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    117096273 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    117096273 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    117096273 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117096273 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    117096273 (MAPK12)
   05161 Hepatitis B
    117096273 (MAPK12)
   05171 Coronavirus disease
    117096273 (MAPK12)
   05163 Human cytomegalovirus infection
    117096273 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117096273 (MAPK12)
   05169 Epstein-Barr virus infection
    117096273 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    117096273 (MAPK12)
   05135 Yersinia infection
    117096273 (MAPK12)
   05133 Pertussis
    117096273 (MAPK12)
   05152 Tuberculosis
    117096273 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    117096273 (MAPK12)
   05140 Leishmaniasis
    117096273 (MAPK12)
   05142 Chagas disease
    117096273 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    117096273 (MAPK12)
   05020 Prion disease
    117096273 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    117096273 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117096273 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    117096273 (MAPK12)
   05415 Diabetic cardiomyopathy
    117096273 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    117096273 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    117096273 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    117096273 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    117096273 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tfn01001]
    117096273 (MAPK12)
Enzymes [BR:tfn01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     117096273 (MAPK12)
Protein kinases [BR:tfn01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   117096273 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1
Other DBs
NCBI-GeneID: 117096273
NCBI-ProteinID: XP_033089384
Position
Unknown
AA seq 538 aa
MGPAPWNHGQSGLEPRVSAGAAPSPDSTPRAGKFSQRGEADRGISAPRPALGRDKAAGRR
SPPPALPPRLRPSPGGGRLGFPEGPEGGRGHHVRAARGPVGPRAGEGPCAAWAGVGPGSA
PGTSPRKGPGAGAPQRRAGEQREVGPGRAPRKPRRSRVPGPGGTARGLCGVGGSRACHEL
SAACPQWLLPPGGDQDGLGGARRVPGPAAPRPWTAAPVLRWPSRSCIGPSSPSCSPSAPT
ASCACSNTCVTRTYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHR
VSPGGGASHQPSPSAIPRLHVLPDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTR
WYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEF
VQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAAEALAHP
YFESLHDTEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGARVSKETAL
NT seq 1617 nt   +upstreamnt  +downstreamnt
atgggccctgcgccctggaaccatgggcagtcaggactggagcccagggtctcagcagga
gctgccccctcccccgactccacccccagagcggggaagttcagccaaaggggagaggct
gacaggggtatctccgcgccgcgtccggccctaggtcgggacaaagccgcggggcggcgc
tcccctccccctgcgcttccccccaggctccggccctcccccggcggcggccgcctcggg
tttccggaggggccggagggcgggcgagggcatcacgtgcgcgccgcccgcgggccggtt
ggtccccgggcgggggaggggccgtgcgctgcctgggccggggtcgggccagggtcggca
cctgggacatccccgaggaaagggccgggagcaggagcgccccagcggcgggcgggcgag
cagcgcgaagtcggcccggggcgcgcgccgaggaagccccgccgatcccgggtccccggt
cctgggggcaccgcccgcgggctctgcggggtgggcggctcccgggcctgccatgagctc
tccgccgcctgcccgcagtggcttttaccgccaggaggtgaccaagacggcctgggaggt
gcgcgccgtgtaccgggacctgcagcccctcggccgtggacagccgcaccggtgctaagg
tggccatcaagaagctgtatcggcccttccagtccgagctgttcgccaagcgcgcctacc
gcgagctgcgcctgctcaaacacatgcgtcacgagaacttacctggtgatgccgttcatg
ggcaccgacctgggcaagctcatgaaacatgagaagctgggcgaggaccggatccagttc
ctcgtgtaccagatgctgaaggggttgaggtatatccatgctgccggcatcatccacaga
gtgagtcctggtggaggagccagccatcagccctcccccagcgcaatcccccgcctccac
gtcctacctgacctgaagcctggcaacctggctgtgaacgaagactgtgagctgaagatc
ctggactttggcctggccaggcaggcagacagcgagatgactgggtatgtggtgacccgg
tggtaccgggcacccgaggtcatcttgaattggatgcgctacacgcagacggtggacatc
tggtctgtgggctgcatcatggcggagatgatcacaggcaagacgctgttcaagggcagc
gaccacctggaccagctgaaggagatcatgaaggtgacagggacgcctccagctgagttt
gtgcagcggctgcagagtgatgaggccaagaactacatgaagggcctccccgagttggag
aagaaggattttgcctccatcctgaccaatgcaagccctctggctgtgaacctcctggag
aagatgctggtgctggatgcggagcagcgggtgacagcagccgaggcactggcccatccc
tacttcgagtccctgcacgacacggaagacgagccccaggtccagaagtatgacgactcc
tttgatgacgtggaccgcacgctggatgaatggaagcgtgttacttacaaagaggtgctc
agcttcaagcctccccggcagctgggagccagggtctccaaggagacagctctgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (3)   
   Pfam (3)   
All databases (22)   

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