KEGG   Thermobifida halotolerans: NI17_023900
Entry
NI17_023900       CDS       T08032                                 
Symbol
ilvC
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
thao  Thermobifida halotolerans
Pathway
thao00290  Valine, leucine and isoleucine biosynthesis
thao00770  Pantothenate and CoA biosynthesis
thao01100  Metabolic pathways
thao01110  Biosynthesis of secondary metabolites
thao01210  2-Oxocarboxylic acid metabolism
thao01230  Biosynthesis of amino acids
Module
thao_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
thao_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:thao00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    NI17_023900 (ilvC)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    NI17_023900 (ilvC)
Enzymes [BR:thao01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     NI17_023900 (ilvC)
SSDB
Motif
Pfam: KARI_N KARI_C F420_oxidored 2-Hacid_dh_C NAD_binding_2 AdoHcyase_NAD UDPG_MGDP_dh_C PDH_N NAD_binding_7 GFO_IDH_MocA ApbA
Other DBs
NCBI-ProteinID: UOE19692
UniProt: A0AA97LWU1
Position
5441475..5442470
AA seq 331 aa
MAAQMYYDDAADLNLIQGRTVAVIGYGSQGHAHALSLRDSGVDVRVGLPEGSKSRAKAEE
DGLRVVTPAEAAQEADLIMVLVPDHIHRDLYANEIAPHLNEGDALFFGHGFSIRYGLIQP
PAGVDVAMVAPKGPGHLVRRQFEAGRGVPVLVAVEKDASGSAWDLALSYAKAIGGTRAGA
LKTTFTEETETDLFGEQAVLCGGVSELIKAGFATLVEAGYQPEVAYFECLHEMKLIVDLM
YEGGLSKMYWSVSDNAEYGGYTRGPRVVTEATREEMRKILGEIQDGTYARELVEEFDNGR
PNFLKRREAEQNEQIEKVGSELRPLMSWLKS
NT seq 996 nt   +upstreamnt  +downstreamnt
gtggcagcacagatgtactacgacgacgccgccgacctgaacctcatccaggggcgcacc
gtcgccgtcatcggttacggcagccaggggcacgcgcacgcgctgtcgctgcgggattcc
ggggtcgacgtgcgggtcggtctgccggaggggtccaagagccgggccaaggccgaggag
gacggcctgcgggtcgtcaccccggcggaggcggcgcaggaggccgacctcatcatggtt
ctggtgcccgaccacatccaccgcgacctgtacgccaacgagatcgccccgcacctcaac
gagggcgacgcgctgttcttcgggcacggcttcagcatccgctacggcctgatccagccg
cccgcgggtgtggacgtggcgatggtcgcccccaagggccccggccacctggtccgccgc
cagttcgaggcggggcgcggagtcccggtgctggtcgccgtggagaaggacgcctccggc
tcggcctgggacctggcgctgtcctacgccaaggccatcggcggcacccgcgcgggcgcg
ctcaagaccaccttcaccgaggagaccgagaccgacctgttcggtgagcaggccgtgctg
tgcggcggtgtgtccgagctgatcaaggccgggttcgccacgctggtcgaggcgggctac
cagcccgaggtggcctacttcgagtgcctgcacgagatgaagctcatcgtcgacctcatg
tacgagggcggcctctccaagatgtactggtcggtgtcggacaacgccgagtacggcggc
tacacgcgcggcccgcgggtcgtcaccgaggccacccgcgaggagatgcgcaagatcctg
ggcgagatccaggacggcacctacgcccgcgaactggtcgaggagttcgacaacggtcgg
ccgaacttcctgaagcgccgtgaggccgagcagaacgagcagatcgagaaggtgggcagc
gagctgcgtccgctgatgagctggctgaagtcctga

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