KEGG   Takifugu rubripes (torafugu): 101066166
Entry
101066166         CDS       T02386                                 
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
tru  Takifugu rubripes (torafugu)
Pathway
tru00562  Inositol phosphate metabolism
tru01100  Metabolic pathways
tru04012  ErbB signaling pathway
tru04068  FoxO signaling pathway
tru04070  Phosphatidylinositol signaling system
tru04081  Hormone signaling
tru04140  Autophagy - animal
tru04145  Phagocytosis
tru04150  mTOR signaling pathway
tru04210  Apoptosis
tru04218  Cellular senescence
tru04370  VEGF signaling pathway
tru04510  Focal adhesion
tru04517  IgSF CAM signaling
tru04518  Integrin signaling
tru04620  Toll-like receptor signaling pathway
tru04625  C-type lectin receptor signaling pathway
tru04810  Regulation of actin cytoskeleton
tru04910  Insulin signaling pathway
tru04914  Progesterone-mediated oocyte maturation
tru05100  Bacterial invasion of epithelial cells
tru05132  Salmonella infection
tru05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:tru00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101066166
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    101066166
   04370 VEGF signaling pathway
    101066166
   04068 FoxO signaling pathway
    101066166
   04070 Phosphatidylinositol signaling system
    101066166
   04150 mTOR signaling pathway
    101066166
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    101066166
   04517 IgSF CAM signaling
    101066166
   04518 Integrin signaling
    101066166
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    101066166
   04140 Autophagy - animal
    101066166
  09143 Cell growth and death
   04210 Apoptosis
    101066166
   04218 Cellular senescence
    101066166
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101066166
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101066166
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101066166
   04625 C-type lectin receptor signaling pathway
    101066166
  09152 Endocrine system
   04910 Insulin signaling pathway
    101066166
   04914 Progesterone-mediated oocyte maturation
    101066166
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    101066166
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101066166
   05100 Bacterial invasion of epithelial cells
    101066166
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tru04131]
    101066166
Enzymes [BR:tru01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     101066166
Membrane trafficking [BR:tru04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    101066166
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_C2 PI3K_p85B ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 101066166
NCBI-ProteinID: XP_003978260
UniProt: H2SAV2
Position
20:15247751..15262552
AA seq 1068 aa
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKHPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEVAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAVEDHASRTISREVGLNYTLSGQSNRAARDHILTEGDSEQLRQLTNRDPL
SEITEQEKDFLWRNRYYCMNIPEILPKILLAVKWNSRDEVAKMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECVKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctcccaggccatcctcgggggagctatggggcatccacctaatgcctcccaggatc
ctggtggactgtctcctgcccaacgggatgattctgaccttggagtgtctccgtgaggca
acgctcatcaccatcaaacatgagctctttaaggaggcaaggaaatatcccctccatcac
ctcctgcaggaggagacctcctacatttttgtcagtgttacacaggaagcagagcgggag
gagttctacgatgagactcggagactctgtgacctccgactcttccaaccattcctcaaa
gtcattgaaccagttggcaacagggaagaaaagatcctcaacagggagattggttttgcc
atcggtatgcccgtatgtgagtttgacctggtgaaagatcccgaggttcaggacttcagg
agaaacatcctgaatgtctgtaaagactctgtggagttgcgagacgccagtgggccccac
agcagagcgctctatgtttacccgcccaacgtagaatcctcacaggaactccccaaacac
atctacagcaaactggacaaaggtcagattatcgttgtgatttgggtcatcgtttctcca
aacaacgacaaacagaaatatacactgaagatcaaccacgactgtgtgcctgagcaggtg
atagcagaggccatccgtaagaagacacgcagcatgctgctgtcaccagagcaactgaag
atgtgcgttcaggaatatcagggtaaatacatcctcaaggtctgtggctgtgacgagtac
ctgctggagaaacatcccatcagccagtataagtatatccgtagttgcatcatgttgggc
aggatgcctaatctgatgctaatggctaaagacagcctgtacagccagttacccacagat
aactttgtcatgccatcctactcccggcgcatctccacggcaacatcgtatatgaatggc
gaggtagctgccaagtcactgtggactatcaatggaacactgcgaatacgaatcctatgt
gccacctacgttaatgtgaatatacgggacatagacaagatatatgtgagaacaggcatt
tatcatggaggtgaacagatgtgtgataatgtaaacacacaaagggtaccatgctccaat
cccaggtggaatgagtggctcacgtatgatatgtacatctctgacatcccacgtgctgcc
aggctttgcctttccatttgctctgttaaaggcagaaagggagcaaaggaggaacactgt
ccactagcttggggtaatattaacctgtttgactacactcatacactggtggccaacaag
atggctctgaacctctggcctgtgcctcatgggcttgaagatctccttaaccccatagga
gtaactggatccaatccaaataaggaaaccccgtgcctcgaactggagtttgaccacttc
agtagttcagtcaaatacccggacatgaatgcagttgaggatcacgctagccggaccatc
tcaagagaagtggggctaaattacaccctctctggacagagtaaccgtgcagccagagat
catatcctgacagagggcgactctgagcagctgagacagctcacaaacagagaccctctt
tcagaaatcactgagcaggagaaagacttcctctggagaaacaggtactactgcatgaac
atccctgagatacttcccaagatccttctcgcagtcaaatggaactccagagatgaagtt
gcaaagatgtactgcctactaaaggaatggccctccatccgtcctgaacaggccatggag
ctgttggactgtaactatcctgaccctatggtcaggcactttgctgtacgctgccttgat
aaatacctgactgatgacaaactctcccagtacctcatccagcttgtacaggtgctaaag
tatgaacagtatctcgacaatcccttggtccgttttctcctgaagaaagctctgaccaat
caaagaataggacatttctttttctggcatcttaaatcagaaatgcacaataagacagta
agccagaggtttggtttgcttttggaggcttactgcagggcttgtggcatgtaccttaag
catctcagcaggcaggtagaagccatggagaagctcattaacctcactgatatcctcaaa
caggaaaagaaggatgagacccagaaggtccagatgaggtttctggttgaccagatgaag
agaccagactatatggatgctttacagaatttcacctctcctctcaaccctgcacaccag
ctggggaacctgaggttagatgagtgcagaattatgtcatcagccaagagaccactgtgg
ctcaattgggagaatcctgacatcatgtccgagctgctttttcagaacaatgagatcatc
ttcaaaaatggagatgacctacggcaggacatgctgacattgcagattataaaaatcatg
gagaatatttggcagaatcagggactggatttacggatgcttccgtatggctgtctgtcg
ttgggcgattgtgtcggtctgattgaagtggttcgcagctcccacaccatcatgcagatt
cagtgtaaaggaggcttgaaaggagccctgcagttcaactccaacaccctgcatcagtgg
ctcagggacaagaacaagggcgagatgtacgatatggccgttgatctgtttacgaggtcc
tgcgctggctactgtgtagctacatttatccttgggataggagacaggcacaacagcaat
attatggtcaaagatgatggacagttatttcatatagattttggccactttctggatcat
aagaagaagaagtttggctacaagagagagcgcgtgcccttcgtgctgacacaagacttt
ctcattgtcatcagcaaaggatcccaagagtgtgtgaagaccaaagagtttgagagattc
caggagatgtgctataaagcatacctggcgatccggcagcatgctaatctcttcatcaac
ctgttctccatgatgctgggctctggcatgcctgagctgcagtcatttgatgacattgcc
tacattaggaaaacactggccctggagaaaactgagcaggaggcgttggactacttcatg
aaacagatgaacgatgctcatcacggtggatggaccaccaagatggactggatattccac
acaattagacaacatgcactaaactga

  All links  
Gene (17)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (7)   
   Pfam (7)   
All databases (45)   

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