KEGG   Thamnophis sirtalis (common garter snake): 106544747
Entry
106544747         CDS       T06107                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
tsr  Thamnophis sirtalis (common garter snake)
Pathway
tsr00562  Inositol phosphate metabolism
tsr01100  Metabolic pathways
tsr04020  Calcium signaling pathway
tsr04070  Phosphatidylinositol signaling system
tsr04081  Hormone signaling
tsr04082  Neuroactive ligand signaling
tsr04261  Adrenergic signaling in cardiomyocytes
tsr04270  Vascular smooth muscle contraction
tsr04310  Wnt signaling pathway
tsr04371  Apelin signaling pathway
tsr04540  Gap junction
tsr04621  NOD-like receptor signaling pathway
tsr04912  GnRH signaling pathway
tsr04916  Melanogenesis
Module
tsr_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:tsr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    106544747 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    106544747 (PLCB2)
   04371 Apelin signaling pathway
    106544747 (PLCB2)
   04020 Calcium signaling pathway
    106544747 (PLCB2)
   04070 Phosphatidylinositol signaling system
    106544747 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    106544747 (PLCB2)
   04081 Hormone signaling
    106544747 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    106544747 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    106544747 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    106544747 (PLCB2)
   04916 Melanogenesis
    106544747 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    106544747 (PLCB2)
   04270 Vascular smooth muscle contraction
    106544747 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tsr04131]
    106544747 (PLCB2)
Enzymes [BR:tsr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     106544747 (PLCB2)
Membrane trafficking [BR:tsr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    106544747 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    106544747 (PLCB2)
SSDB
Motif
Pfam: PH_14 PI-PLC-Y PLCB1-4-like_EFh PI-PLC-X EF-hand_like C2 Sec3_CC
Other DBs
NCBI-GeneID: 106544747
NCBI-ProteinID: XP_013916586
UniProt: A0A6I9XS61
Position
Unknown
AA seq 697 aa
MSVLSPILTPPKVKKYMIEGERFIKWDDESANAHPVILRVDPKGFYLYWTFQNKETEFLD
ITSIRDTRVGKFAKIPKNHKLREVFNLDFPNSNFLHKILTVVSGPDMVDLTFHNFVSYKE
NVGKNWADDIMDFIRNPFIYNASRYTFLEKILVKLKMQLNAEGKIPVKNIFQMFPADRKR
VEAALSACHLPQGKNDGINPEDFPEKVYKTFLMNLCPRPDIDEIFTSHHSKAKPYMTKDH
LTKFINKKQRNSQLNDTLFPPAKPDRVQGLIEKYEPSGMNIQRGQLSPEGMVWFLCGPEN
SIVSQNKLLLYQDMNQPLSHYFINSSHNTYLTVKPVEEGEKVPEAERNLENLNEEEIKKL
QSDEGTAGLEVTAFEEMSSLVNYIQPIKFESFEISAQKNQSFVVSSFTELKAYELLTRSP
IQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNVGCQMVALNFQTSDVPMQQNMALFEFN
GQSGYLLKHDFMRRPDKHFDPFSVDRIDVVVASTLSVTIISGQFLSERSVKSYVEVELFG
LPGDPKRRYRTKVTPNANSINPIWNEDPFVFEKILMPELASLRIVVLEEGGKFIGHRIIP
VTAVCSAGQFSGLSSPEMYRQTLLAGCRCVELDCWKGRLPDEEPIITHGYTMTTEILFKI
FTSSRLILILKALLNSGSRCTTGITSILMLLHSHIGG
NT seq 2094 nt   +upstreamnt  +downstreamnt
atgtcagtgcttagtcctatcctgacccctcctaaggtgaagaagtacatgattgaaggt
gaacgctttatcaaatgggatgacgaatctgcaaatgcacaccctgtcattctacgggtg
gatccaaaaggattttatctgtattggacttttcaaaataaggaaactgaatttttggat
attacaagcatccgagacactagagtggggaaatttgcaaagattcctaaaaatcacaag
ctccgagaagttttcaacttggattttccaaacagcaactttcttcacaagatattgact
gtggtttctggtcctgatatggtggacctcacatttcacaattttgtttcttataaagaa
aatgttggaaagaactgggcagatgatatcatggacttcattaggaacccctttatatac
aatgcttcccgctacactttcctggagaaaatcctggttaaactgaagatgcagctgaat
gctgaggggaaaattcctgtcaagaatatttttcaaatgtttcccgcggacagaaaaagg
gtagaagcagcattaagtgcctgtcatcttccacaggggaagaatgatggtatcaatcca
gaagactttcctgaaaaagtatataaaacattcctgatgaacctgtgtcctcggccagat
attgatgaaatatttacctcacaccattcaaaagccaagccgtacatgacgaaagatcac
ttgacaaaatttatcaacaagaaacagcgaaattcccaactcaatgacacgcttttccct
cctgccaaaccagacagagtacagggtctcatagaaaaatatgagcccagtgggatgaat
attcaaagagggcaactatctcctgagggaatggtttggttcctgtgtggtcctgaaaac
agcatcgtgtctcagaacaaactgctgctataccaagatatgaaccagccactctcccat
tatttcatcaactcatcccacaacacttacctaacagtcaagccagttgaggagggtgaa
aaagttcctgaagcagagagaaatttggaaaacctaaatgaggaagagattaaaaagcta
cagtctgatgagggaactgcaggtctggaagtgactgcctttgaagaaatgtccagtctg
gtgaattacattcagcccatcaaatttgagagttttgaaatttcagcacagaaaaaccag
agttttgttgtttcctccttcactgagttgaaggcttatgagttgttgaccaggtcaccc
atccagtttgtcgactacaacaaaagacagatgagccgaatttatcccaaaggtactcgg
atggattcttctaactatatgccacagatgttctggaatgttgggtgtcaaatggtggca
ttaaactttcagacaagtgatgtcccaatgcagcagaacatggctctgtttgaattcaat
gggcaaagtggctatcttcttaaacatgacttcatgcgtcgtccagacaagcactttgat
cctttttcagtggatcggattgatgtagttgtggcaagcactttgtcagtcaccatcatt
tctggccagttcctttcagaacgcagcgtgaagtcctacgtagaggtagagttgtttggc
ctaccaggagatccaaagcgtagatacagaaccaaagtgacaccaaatgccaactcaatc
aaccctatatggaatgaagacccttttgtgtttgaaaagattttgatgccagagttggct
tctctcagaatagtagttttggaagaaggtgggaagttcattggtcaccgcattatccca
gttactgctgtgtgctctgctggacagttttctggactctcgtctcctgaaatgtatcgc
caaactctcttggctggttgtcgttgtgtggaacttgattgctggaagggacgtcttcca
gatgaggaaccaatcatcacccacgggtacactatgacaactgaaatactattcaagatc
ttcacatcctccaggctgatcttgatcttgaaagccttacttaactcaggatcaagatgt
acaactggtattaccagcatcctgatgttactacattcccacattggaggataa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (12)   

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