KEGG   Thunnus thynnus (Atlantic bluefin tuna): 137175237
Entry
137175237         CDS       T11154                                 
Symbol
plcb3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
tty  Thunnus thynnus (Atlantic bluefin tuna)
Pathway
tty00562  Inositol phosphate metabolism
tty01100  Metabolic pathways
tty04020  Calcium signaling pathway
tty04070  Phosphatidylinositol signaling system
tty04081  Hormone signaling
tty04082  Neuroactive ligand signaling
tty04261  Adrenergic signaling in cardiomyocytes
tty04270  Vascular smooth muscle contraction
tty04310  Wnt signaling pathway
tty04371  Apelin signaling pathway
tty04540  Gap junction
tty04621  NOD-like receptor signaling pathway
tty04912  GnRH signaling pathway
tty04916  Melanogenesis
Module
tty_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:tty00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    137175237 (plcb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    137175237 (plcb3)
   04371 Apelin signaling pathway
    137175237 (plcb3)
   04020 Calcium signaling pathway
    137175237 (plcb3)
   04070 Phosphatidylinositol signaling system
    137175237 (plcb3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    137175237 (plcb3)
   04081 Hormone signaling
    137175237 (plcb3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    137175237 (plcb3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    137175237 (plcb3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    137175237 (plcb3)
   04916 Melanogenesis
    137175237 (plcb3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    137175237 (plcb3)
   04270 Vascular smooth muscle contraction
    137175237 (plcb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tty04131]
    137175237 (plcb3)
Enzymes [BR:tty01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     137175237 (plcb3)
Membrane trafficking [BR:tty04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    137175237 (plcb3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    137175237 (plcb3)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh C2 EF-hand_like
Other DBs
NCBI-GeneID: 137175237
NCBI-ProteinID: XP_067437081
Position
22:complement(8642936..8695214)
AA seq 1257 aa
MAGAKPGVHALQLKPVSVHEALKKGGKFIKWDEEPNSGPPTLVTLKVDPDGFFLYWTGGS
NLEVEILDISTIRDTRTGKYAKLPKDPKVRDVLGCGKAESVEGKLVTVVHGNDLVNISFL
NFQAMQEDTAKIWTDELFTLATNILSQNSSRNTFLLKAYTKLKLQVNQDGKIPVKNILKM
FSDKKRVETALEQCGLVVNKSEGIKPDDFTWEAFQKFLDTLSLRPEIQSIFEESGSKRKP
FISLDQLMDFINRRQRDSRLNEVLYPPLKREQVRQIMEKYETNTSQLERDQISLQAFSRY
LGGEENGITPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGCR
CVELDCWKGRPPDEEPYITHGFTMTTEISFKEVIEAIAESAFKTSPYPVILSFENHVDSA
KQQAKMAEYCRTIFGDALLIDPLEKYPLIPGQALPSPQEMLGKILIKNKKKHHHRPSSGG
SIRRRELEEQSSPNNECPLTDGEGSHLLSNGEEKLAERMVKDSEPRKSIGGEGESEEDED
DEPSTELKKPNSDEGTASSEVNATEEMSTLVNYIEPVKFKSFEVANKRKKFFEMSSFVET
KGVDTLKSSPIEFVEYNKNQLSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQSLDLPM
QLNMGVFEYNGRSGYLLKPEFMRRIDKHFDPFTENIVDGIVANTVKIRVISGQFLTDKKV
GVYVEVDMFGLPVDTKRKYRTKTSNGNSLDPVWDDEMYVFNKVVLPTLASLRIAVFEENG
KFIGHRILPVSAIRPGYHYINLKNELNQPLLLSSLLVCTEAQDYIPNEHQEYAEALTNPI
KHVSQLDKRETQLAVLIEDNSEHVPEQPKEGEPRRESDAIPGGRLPSPFHNVPPCSLEDA
SDIINVPIPAQSQKEDLIATVLGDIQVQSIEELRQQKNYLKLLKKHGKELKDLHKKHLKK
VWNLSKEQKSRNSQLQSDTQRRRSQMEKHLKRSIKKNEPPEPMQQELTALDQELEKQVVQ
LREWQMQELLKLRQQQHTLEREKQQTHLQEAFQKLKETAHECQAAQLKKLRETCEKEKKE
LQKILDRKRQNSISEAKSRDKDKAETELNDINRKHIQDSVTLIRRLEEAQTRRQDKLMLR
QREVLQHIDEEFPLLQSQLERELDEESKRLPEEICQHLQSELQNKGLRKDALFSSLSNHS
SPSSGSGPPSNCSTPSYPSTPNRSTWNRSLDNSTASLADSTSSSATPVLSEGEMSFS
NT seq 3774 nt   +upstreamnt  +downstreamnt
atggccggggccaagccgggagtccacgcgctgcagctcaaacccgtgtccgtccacgaa
gcgctgaagaaggggggcaaattcatcaaatgggacgaggagcctaacagcgggccccca
accctggtaacgctgaaagttgacccagatggattcttcctctactggactggagggtcc
aacctggaggtagagattctggacatcagcaccatcagggacacccgaacaggaaaatat
gcaaagctaccaaaggaccccaaggtgcgggatgttctcggttgcggtaaggctgaaagt
gtagaagggaagctggtaaccgttgtccatggaaacgacctggtcaacatctccttcctc
aacttccaggctatgcaggaagacacagccaagatttggacagatgagctgttcactttg
gccacaaacatactttcccagaattcatcgcggaataccttcctcctcaaagcgtacact
aagttaaagttgcaggtgaatcaggacgggaagattccagtgaagaatattctcaagatg
ttttcagataaaaagagagtggagacggctctagagcagtgtggcctcgtcgttaacaag
tcagagggaataaagccagatgatttcacatgggaggccttccagaagtttcttgacact
ctcagtctccggcctgagatacaaagcatctttgaagaaagtgggtccaagaggaagccg
ttcatctctttggaccagctgatggacttcatcaaccgcaggcagcgagactccagactg
aacgaggtgctgtaccctccgctgaaaagagagcaggtccgacagatcatggagaaatat
gagaccaacaccagccagctggagagagaccagatcagtttgcaggctttcagtcggtat
ctgggaggagaggaaaacggcatcacacctccagagaggctggatatcatcgacgatatg
aaccaaccgctgtctcactactttatcaactcctcacacaacacatacctcacagtgggt
cagctgacaggtctgtcctcagtagagatgtacaggcaggtgctgctgaccggctgtcgc
tgtgtcgagctggactgctggaagggccgaccgccagacgaggagccttacatcacccat
gggttcaccatgaccactgagatatctttcaaggaggtgattgaagcaatagcagagagc
gctttcaagacctcgccgtaccctgtcatcctgtccttcgaaaaccacgtagattcggcc
aagcagcaagccaagatggcggagtactgcaggaccatatttggagacgcgctgctcatt
gatccactggagaaatatccgctaatcccagggcaggcgcttccctcgccgcaggagatg
ctggggaagattctcatcaaaaacaagaagaagcaccaccacaggccttccagtggcggc
agcattcgacgcagggagctggaggagcagtcgtcgcccaacaacgagtgccctctgaca
gatggcgagggaagccatctcctgtccaacggagaggagaagctggctgagaggatggtc
aaagattcagagccccgcaagtccatcggaggtgagggagagagcgaggaggacgaagat
gatgagccatcgaccgaactgaaaaagccaaactctgacgagggtacagccagcagtgaa
gtgaatgccacagaggagatgtcgactctcgtcaactacatcgaacctgtcaaatttaag
agctttgaggtggcaaacaagaggaagaagttctttgagatgtcgtcgtttgtggaaaca
aaaggcgtggacacgctaaagagctcccctatcgagtttgtcgagtacaataagaatcag
ctgagccgaatctaccctaaaggaacgagggtggacagctccaactacatgcctcagctc
ttctggaacgtcggctgccagatggtggcactaaacttccagagcctcgacctccctatg
cagctgaacatgggggtgtttgagtataacggccgcagtggctacctgctgaaaccggag
ttcatgagaaggatagacaaacactttgacccgtttacggagaacatcgtggatggaata
gtcgccaatactgtcaaaattagggtgatctcaggccagttcctgacagataagaaggtg
ggcgtttatgtggaagtggacatgtttggacttcctgtagatacaaaacggaagtataga
accaaaacgtccaatgggaactcgctggaccccgtgtgggatgatgagatgtatgtcttc
aataaggtggtcctccctacactggcctctctaaggatagcagtgtttgaggaaaacggg
aagtttatcggacaccgtatcctccccgtgtctgccattagacctggctaccactacatc
aacctgaagaatgagttaaaccagcctctcctgctgtcctctctgctggtgtgcactgag
gctcaggactacatccctaatgaacaccaggagtacgcagaggccctgaccaaccccatt
aaacacgtcagtcagttggataagagagagacacagctggctgttctcattgaggacaac
agtgagcatgtccccgaacagcccaaagagggagagcccaggagagagagtgacgccatt
ccgggaggtcgactcccctccccctttcacaacgtccctccctgctcattggaagatgct
tctgacatcatcaacgtacctataccggcacaaagtcagaaggaggacctcatagccaca
gttctgggagacatacaggtccagtctatagaggagttgaggcagcagaaaaactatttg
aagcttctgaagaaacatggcaaagaactcaaagatctgcataagaaacacctcaagaag
gtgtggaatctgagtaaggagcagaagagtcggaacagtcagcttcaatctgacacccag
aggaggcgcagtcagatggagaaacacctcaaacgtagcatcaagaaaaacgagcctccg
gagccgatgcagcaggagttgacggcgttggatcaagagcttgagaagcaggtggtccag
ctgagggaatggcagatgcaagagctgctgaagctccgacagcagcaacacacgctggaa
agagagaagcaacaaacacatctgcaagaggccttccagaagttaaaggagacggcccat
gaatgccaagcagctcagctcaagaagctcagggagacgtgcgagaaggagaagaaagag
ctccagaaaatcctagacaggaagcggcagaacagcatcagtgaagccaagagccgtgac
aaagacaaggctgaaaccgaactgaatgacatcaacaggaaacatattcaggattctgtc
accttaatccgaaggctggaggaggctcagaccaggagacaggataagctgatgctgagg
cagcgggaggtgttgcaacacatagatgaggaatttccactgctccagtctcagttggag
agggaactggacgaggagtctaagcgactaccggaggaaatctgccagcacctgcagtcg
gagctccaaaacaaaggtctccgaaaggacgccctgttctcatctttgtctaatcatagc
agccccagctctggctcgggcccgccctccaactgctccacaccctcctacccgtcaacg
cccaatcgaagcacctggaataggagcctggacaatagcactgcctcattggccgattcc
acgtcctcgtccgccacccctgtcctgtcggagggggagatgtcgttcagttag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (11)   

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