KEGG   Thunnus thynnus (Atlantic bluefin tuna): 137197342
Entry
137197342         CDS       T11154                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
tty  Thunnus thynnus (Atlantic bluefin tuna)
Pathway
tty00562  Inositol phosphate metabolism
tty01100  Metabolic pathways
tty04020  Calcium signaling pathway
tty04070  Phosphatidylinositol signaling system
tty04081  Hormone signaling
tty04082  Neuroactive ligand signaling
tty04261  Adrenergic signaling in cardiomyocytes
tty04270  Vascular smooth muscle contraction
tty04310  Wnt signaling pathway
tty04371  Apelin signaling pathway
tty04540  Gap junction
tty04621  NOD-like receptor signaling pathway
tty04912  GnRH signaling pathway
tty04916  Melanogenesis
Module
tty_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:tty00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    137197342
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    137197342
   04371 Apelin signaling pathway
    137197342
   04020 Calcium signaling pathway
    137197342
   04070 Phosphatidylinositol signaling system
    137197342
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    137197342
   04081 Hormone signaling
    137197342
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    137197342
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    137197342
  09152 Endocrine system
   04912 GnRH signaling pathway
    137197342
   04916 Melanogenesis
    137197342
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    137197342
   04270 Vascular smooth muscle contraction
    137197342
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tty04131]
    137197342
Enzymes [BR:tty01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     137197342
Membrane trafficking [BR:tty04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    137197342
 Endocytosis
  Macropinocytosis
   Phospholipase C
    137197342
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 DUF4277
Other DBs
NCBI-GeneID: 137197342
NCBI-ProteinID: XP_067466789
Position
14:complement(24794216..24823216)
AA seq 1161 aa
MASAQPGVHALKLQPPSVSHTLRNGSNFTKWDEDLSTVTPVTLHVDPHGFYLYWTDQNKE
TELLDLTHIKDVRTGRSTKTPKEAKLRELLDVGNLVGRLENRMVTVVTASDHVNVNQLNF
IATQEEEAKVWCEELFSLSSNLLSYNLNRDQSLLKAYVRLTLQLNTEGRIPVKNIGRLFS
SDRKKVENALENCRLPYGRGDSVKLEDFTLEVYRSFLDCLCPRPELGNIFKLQGANDGSL
SVDQMTDFINNKQRDPRLNEILYPPLRPAQTHSLIERYQHDQELLKQGVISLQAFTSYLS
SDENGVIPPEKLDQSEDMSFPLSHYFINSSHNTYLTAGQLAGSSSVEMYRQVLLAGCRCV
ELDVWKGRTNEEEPVITHGFTMTSEIPFKEVIEAIAECAFKTSPFPVILSFENHVDSLKQ
QAKMAEYCQSIFGEALLIDPLDKYPLESGVPLPSPQELMGKILIKNKKSHKPPNNTDTKR
LTDQPANQSNEPVSPSNNTGEMEAESEEDDDDEDDDGKKGSAEREAVATEEMSTLVNYVQ
PTKFNSFEASKKAARCYNMSSFVETKALEHLTKSPVEFVEYNKSQLSRIYPKGTRVDSSN
FMPQLFWNAGCQLVALNYQTIDLSMQLNLFMFEYNGRSGYRLKPEFMRRPDKHFDPFTEN
TVDGIVANTLSVKVISGQFLTERRVGVYVEVEMFGLPVDTRRKALKTKTSQNNNAINPVW
DEEPIMFKKVILPTLASLRIAAFEEGGKFIGHRIIPVSAIRPGYRYIGLRNEKNQSLILP
AVFVYIEVKDYVPDTFADVIEALSNPIRYVNLLEQRSKQLAALTLEDGEEDTQTEDEADS
CAERKNDQKSAPLENGLSLASGPAGHTPIATTPKASAANQQAATTDAAKPAAKTEDLVLS
VLIDVPVCTIESLQQSKLYQKEQRRQFKELKELVRRHQKKTSELLREFNNKYKKTARQCS
KSRGSCSDSEKDDRLQQLKDEQQQQLLALRQEQYYSQKYLQREHIKTLTERLSSLAEESH
NAQMKKLKDICDKEKKELKRQMDRRRTEKINQAKTKEKHLAEEEKMEINKSYVNEVVQNI
KRLEETQAKRHDQLVEQHNELLQEIQDQKPKLQGAVEAEFQEKFQCLPGEIEDFLQDRKP
EVRGHSKSRPSTPHETLSEED
NT seq 3486 nt   +upstreamnt  +downstreamnt
atggcgagtgctcagccgggggtccatgcattgaaactccagcctccctctgtctctcac
acgctgaggaacggaagcaacttcactaaatgggacgaggatctgtcaactgtgactcca
gtgactctgcacgtggatccacatggattttacctctactggacggaccaaaacaaggag
acagagttgttggacttgacccacataaaagatgtcagaacgggaagaagcaccaaaaca
ccaaaggaggccaagctgcgggagctgctggatgttggaaacctggttggccggctcgag
aaccgcatggttaccgtggttacggcttcagaccatgtaaacgtcaaccagctcaacttc
atagcgacgcaggaggaagaagcgaaggtgtggtgtgaggaactgttttctctgtcttcc
aacctcctgagctacaatctcaacagagaccaaagtctgctgaaagcgtacgtcaggtta
accctccagctgaacacagaggggagaattcctgtcaagaacatcggtcggctgttttca
tcagacaggaagaaagtagagaatgccttggagaactgcagactgccttacggacggggc
gacagcgtcaaactggaggactttactctggaagtttacaggagttttttagactgtctg
tgtcctcgtccggagctcggcaacatctttaaactgcaaggagcgaatgacgggtcgctg
tcagtcgaccagatgacagacttcatcaacaacaagcagagagacccgaggctgaacgaa
atcctctacccgcctcttcgccccgcgcagacacacagtctgattgagaggtaccaacat
gaccaggagctgctgaaacaaggtgtcatctccctccaggcgttcactagttatctatcc
agtgatgagaacggcgtcatcccaccggaaaaactggatcagtctgaagatatgagcttt
ccgctgtctcactacttcatcaactcatcacataacacatatctgacagcgggccagctg
gcagggagctcctcggtggagatgtacaggcaggttctcctggccggatgccgttgtgtg
gaattagatgtgtggaaaggacgaactaatgaggaggaacctgtgatcacacacgggttc
accatgacatcagaaatccccttcaaggaagtgattgaagccatcgcagagtgcgccttc
aagacctcacctttccccgtcatactgtcttttgaaaatcacgtggactctttgaagcag
caggctaagatggctgaatattgtcaatctatctttggagaagctctgttgatcgacccc
ctggacaaatatcctctggagtcaggtgtccccctacccagtcctcaggagctgatgggc
aaaattctcatcaagaacaagaaatctcacaaaccgcccaataacaccgacaccaagaga
ctgacggaccagcctgccaatcagagcaacgaaccagtatctcctagcaacaacacagga
gagatggaagctgagagtgaggaagatgatgatgatgaagatgatgatggtaaaaagggt
tcagcagagcgggaagccgtggcaacagaggaaatgtcgactctggtaaactacgtccaa
ccaaccaagttcaactcctttgaagcctccaagaaggcagcccgctgttacaacatgtcg
tcttttgtggagaccaaagctttggagcacctcacaaagtcgccagtggagtttgtagaa
tataataaatcccagttgagtcgtatctatccaaaaggaaccagagttgactcgtccaac
ttcatgcctcaacttttctggaacgctggatgtcagctggtggctctcaactaccaaact
atagatttgtccatgcagctgaatctcttcatgtttgagtacaacggtcggagcggctac
agactgaagcctgagttcatgaggcggccagacaaacactttgacccttttacagaaaac
acagtggacggcatcgtagctaacaccctctctgtgaaggtgatttcaggtcagttcctg
actgaacgtagggtgggtgtgtacgtggaggtggagatgtttggacttcctgtggacacc
aggaggaaagcgctgaagaccaaaacctctcagaacaacaacgccatcaacccagtgtgg
gacgaagagcctatcatgttcaaaaaggtgattcttcctactctggcttctctgagaatc
gctgcgtttgaggaaggagggaagtttattggtcatcgaattatcccagtgtctgccata
agaccaggatatcgttatatcggcctgagaaatgagaaaaatcagtctctgattctaccg
gctgtgtttgtctacattgaagtcaaagactacgtcccagacacctttgcagatgtaata
gaggctctgtccaaccccattcgatatgtcaaccttctggagcagaggtccaaacagctg
gcggctctgacgctggaggacggagaggaagacacacagaccgaggatgaagccgacagc
tgtgcagagcgtaagaacgatcagaagtcagcgccgctggagaatggactcagcctcgcg
tccggccccgcaggacacacgcccatcgccacgacgcccaaagcctccgcagccaatcag
caagcagctacaacagatgcagccaaaccagcagcaaagactgaagatctggttttaagt
gttttgatagatgtcccagtgtgcaccatagagagtctgcagcagtccaagctttaccag
aaggagcagagacgtcagtttaaggagctgaaggagttagtgaggagacaccagaagaaa
acctcagagctcctccgagaattcaacaacaaatacaagaagacagccagacagtgcagc
aagagcaggggttcatgttcggacagcgagaaagacgaccgcctccagcagctgaaagac
gagcagcagcagcagcttctggctctgaggcaggaacagtactacagtcagaaatatcta
cagagagaacatatcaaaacgctgacagagcgactgagcagtctggctgaggagagtcac
aacgcccagatgaagaaactcaaagacatctgcgacaaagagaagaaagagttgaagaga
cagatggatcgaaggagaacagagaagatcaaccaggcgaagaccaaagagaaacatctg
gccgaggaggagaagatggagatcaataaatcctacgtcaatgaagtcgtccagaacata
aaacggctcgaggagacgcaggcgaagcgccacgatcagctggtggaacaacacaatgag
ctgctgcaggagattcaagaccagaaaccaaagctgcagggggccgtggaggccgagttt
caggagaagttccagtgtttgcccggagagatcgaagacttcctgcaggacaggaagcca
gaggttagaggtcacagcaagtcccgaccgtcgacccctcacgaaactctgtcggaggaa
gactga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (12)   

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