KEGG   Trichosurus vulpecula (common brushtail): 118827958
Entry
118827958         CDS       T10126                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2
  KO
K02085  adenomatosis polyposis coli protein
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp04310  Wnt signaling pathway
tvp04390  Hippo signaling pathway
tvp04519  Cadherin signaling
tvp04550  Signaling pathways regulating pluripotency of stem cells
tvp04810  Regulation of actin cytoskeleton
tvp04934  Cushing syndrome
tvp05010  Alzheimer disease
tvp05022  Pathways of neurodegeneration - multiple diseases
tvp05165  Human papillomavirus infection
tvp05200  Pathways in cancer
tvp05206  MicroRNAs in cancer
tvp05210  Colorectal cancer
tvp05213  Endometrial cancer
tvp05217  Basal cell carcinoma
tvp05224  Breast cancer
tvp05225  Hepatocellular carcinoma
tvp05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:tvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    118827958 (APC2)
   04390 Hippo signaling pathway
    118827958 (APC2)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    118827958 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    118827958 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118827958 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118827958 (APC2)
   05206 MicroRNAs in cancer
    118827958 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118827958 (APC2)
   05225 Hepatocellular carcinoma
    118827958 (APC2)
   05226 Gastric cancer
    118827958 (APC2)
   05217 Basal cell carcinoma
    118827958 (APC2)
   05213 Endometrial cancer
    118827958 (APC2)
   05224 Breast cancer
    118827958 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    118827958 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118827958 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    118827958 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118827958 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tvp01009]
    118827958 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:tvp03036]
    118827958 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:tvp04812]
    118827958 (APC2)
Protein phosphatases and associated proteins [BR:tvp01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     118827958 (APC2)
Chromosome and associated proteins [BR:tvp03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    118827958 (APC2)
Cytoskeleton proteins [BR:tvp04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     118827958 (APC2)
SSDB
Motif
Pfam: APC_basic Arm_APC_u3 APC_rep APC_N_CC APC_r Arm SAMP Suppressor_APC PEA2_C SSNA1 Mis12 ARM_PUB Sec7-like_HUS JIP_LZII HALZ Par-4_C
Other DBs
NCBI-GeneID: 118827958
NCBI-ProteinID: XP_036590240
Position
1:complement(60088577..60165949)
AA seq 2597 aa
MAAIQYQNGSVVVCHSTAALEEAAAGGGGAPGQPGERARQAPEDAVSMGLLWFLSFLHST
FFGDEGLELGAQDLGSWAIHWHLALGLALPLLRHPGDELRETEAATGNPASPKTNRKDLI
KVQPSCLVCPPSSPLPPGFPADAPQIPASVLEELKMSGPGPTASYEQLVRQVEALSRENT
HLRRELQDNSSHLSKLENETSDMKEVLKHLQGKLEQEARAMVSSGRTELLEQLKALQMDI
TNLYNLKFQPPALVAEPGSQSRSRSRSPEGSPLHCAAPVPAAPGLSKKREESGELSRATV
RLLEELDKERCFLLAEIEKEEQEKLWYYGQLQGLSQRLDELPRSETFSMQTDLIRQQLEF
EAQHIRALMEERFGTSDEMVQRAQIRASRLEQIEKELAEAQAQTQTRERAQQPQPEHQTL
LGAKPTGADGDGEAEVPTHPEDGTGQLSNSKVEVVFWLLSMLATRDKEDMARTLLAMSSS
QESCVAMRRSGCLPLLLQILHDADREAGPAEGAKDARMRANAALHNIIFSQPDEGQAKKE
MRVLHVLEQIRSYSETCWDWLRMQSQDGGQGPEGGAGPVPIEPQICQATCAVMKLSFDEE
YRRAMNELGGLQAVAELLQVDYEMHKMTNDPLNLALRRYAGMTLTNLTFGDVVNKATLCA
RRGCMQAIVAQLASDSEELHQVVSSILRNLSWRADINSKKVLREVGSMTGLMQCALRATK
ESTLKSVLSALWNLSAHSTENKAAICLVDGALGFLVSTLTYKCQSNSLAIIESGGGILRN
VSSLIATREDYRQVLRDHNCLQTLLQHLRSHSLTIVSNACGTLWNLSARSPRDQELLWDL
GAVSMLRNLIHSKHKMIAMGSAAALRNLLTHRPLKYKDTAAVISPGSCMPSLYVRKQKAL
EAELDARHLAEALDTMEKQSLKGQVAKKPPLRHLDSLVKDYASDSGCFDDEDVPALAPGV
EVGNPSVLSMFLNSSFLQGQALPRMPAPRRGPEAEREDGSSGRGSMDAKKGVMDGTAAAA
EKLATKLSVAVAKIDKLVEDISALHTSSEDSFSLSSGDHGLDWPSGPGEVREARAQSCSP
CRLPEAGRREGLGRAHPLLRLKAAYTSLSNDSLNSSSTSDGYCPREHMKPSPRASFVDYR
EELQRYQQRPSRLDLKNIVATQPDRREPPSQESAAPQGPETQEGLQKSSIFPGEWALRKE
SEWPKEREGKLATDSHVHTIKLSPSYQHVPLLEGMAKVGAVPFPSSGGAPTARKQAWLPT
GTLKGTEGLSKIPEKLTAPAPPAPAAETLQKYSVEDTPICFSRCSSLSSLSSADHGMDGR
SRSEDNELDSDSSLEILEEPGPGEGEDDGVEDWRHRGTASLPVAIPAPRGDQAFLSQAQG
DEGASPSRQEDMTPSSSSENYIQETPLVMSRCSSVSSLGSFESPSIASSIQSDPCSEMVS
GTVSPSELPDSPGQTMPPSRSKTPLPERETSQFNLQWENNVKKFMDITDFKERFQLPPDL
DSTIYFTVEKPDENFSCASSLSALPLHEHYVQKDVELKLLPPFPERGGGLHFAGHEKREE
PGREERVEGTRGGRPRLETHSEDDLEILKECISSAMPSRFRKVKTALVPGLPSGKKGLHV
PVYMLVPAHAHASMAARTPRPSRSPYKDEDSFTDSAEGTPVNFSSTTSLSDETLQYPPKD
GQGQRAERREPISRRVTSSHSTPTKMAAAYKHRAACLPLSSRGTEPTRGSLKNLPNLELT
VSRPRSAHSERDSHSRGDSAHLNGGHGDVAFQSLCHTTPTEEAVYCFYENDSDDAPEAPA
RKAPAGARAPKKEHRAGKKETEPKTKVVPPPSTRPRAPPKSQHKLIADETPPCYSLSSSV
SSLSDLDLSDRDGGQPHGKGGLSHLQARKPLHTKPPALAPGRDSSPSSPSLNSDEDLLQR
CIGSAMPKRQRHAVRNRKAERKPKQGVPKATGSKERKAELRRELGEEVGSDRASDLDSVE
WQAIQDGANSIVTWLHQAAAAATSFSREPSSESDSILSFVSGLSVGSTLQLTLGREEQKR
RGKDTGGEVEKKEQNKTADECKKGGEARTLNRRMSRGPEKPNSAQKPVSNLPAVFRGRTV
IYMPTLAKGAPKPRSPPKKTVPKSEPPAKPLTLNQQRSRSLHRPGKISEMTELTLPKRSA
TPPARMAKTPSSGSSQTSTPSQPPSKKSPPSSQISKPVPATGGKAGTNSPQARAPVKALL
SRQHKTQKSPVRIPFMQKPVRKTFPVRNNQPVPEEQGAGRKAGGRLNLVRVASTRSSGSE
SDRSGFLRQLTFIKESSNLLLRHRSETTTPLSQNSSPRRSRPGVPAVFLCSSRCDELKAA
KAGPQPSPRASPGERLPRRTSSESPSRLPVKIATPQPEPFKRYSSSPHINVVKRSGSPAP
TPPQRAEAGGGRRRSDGEAKPLPQVSAREGHNAQSTATKGTWRRIRDEDIPHILKSTLPS
TALPLVGTVQEDSPGPQRKTSDAVVQTEDFSASKTNSSTSPTLENREPPKNAVSIPVNSV
QAPFIGSDVDGLSSKVAAAISFTHEGLTAPAGGFPSSRHSSPSRAARVTPFNYIPSPMVV
PAMTDKSVEKAISLQGE
NT seq 7794 nt   +upstreamnt  +downstreamnt
atggcagctatccagtaccaaaatgggagcgtagtggtctgtcacagcacggctgcactg
gaggaggctgcggcgggtggaggcggagcgcctgggcagccgggcgagcgggcacggcag
gcgccggaggatgcagtctccatggggctgctgtggtttctctccttcctccattccacc
ttctttggggacgagggcttggagcttggggcccaggacttgggatcttgggccattcat
tggcatctggccctgggcctggctctgccccttcttcgccatcctggggatgagctcagg
gagaccgaggcagccacaggcaacccggcaagccccaaaacaaaccggaaggatcttatc
aaggtgcagcccagctgcctggtgtgccctccctcctcacctctgccccctggcttccct
gcagatgcccctcagatcccagcttcggtgctggaggaactaaagatgtcgggaccgggc
ccaacggcttcctatgagcagctggtgcggcaggtggaagccctgagccgggagaacacc
cacctgcggagagaactccaggataactccagtcatctgtcaaagttggagaatgagacc
tctgacatgaaggaggtgctgaagcaccttcaggggaagctggaacaagaagcgagagca
atggtgtcttctgggaggactgagttgttggagcagctgaaagccttgcagatggatatc
accaacttgtacaacctcaagtttcagcccccagctctggttgcagagccaggcagccag
agtcggagccggagccggagccctgagggcagccccctgcactgtgctgcccctgtaccc
gctgctcccggactgtccaagaaaagagaagaatcaggagaattgagcagggccactgtc
cggctgctggaggaactggacaaagagaggtgcttcctgctggcagagattgagaaggaa
gaacaagagaaactctggtattacgggcagctccagggcttgtcccagaggttggatgag
ctacctcgatcagagacgttttccatgcagacagacctgatccgacagcagctggagttc
gaagctcagcacatccgagcgctgatggaagagcgattcgggacctcggacgagatggtg
cagagggctcagatccgagcctctcgcctggagcagattgagaaggagcttgcggaagcc
caggctcagacgcagacccgggagcgcgcgcagcagccacagcctgagcaccagaccctc
ctaggggcaaagccaacaggagcagatggtgatggggaggcagaagtccccacacaccca
gaggatgggaccggccaactcagcaacagcaaggtggaggtggtgttctggttactgtcc
atgctggccacgagggataaggaggacatggcacggaccctcctggccatgtcgagctcc
caggagagctgtgtggccatgcgccgctctggctgcctgccgctcctgctgcagatcctc
cacgatgccgaccgagaggcgggccccgccgagggggccaaggatgcccgcatgcgagcc
aacgcagccctacacaacatcatcttctcccagcccgatgagggccaggccaagaaggag
atgcgagtgctgcatgtgctggagcagatccgctcctactctgagacctgctgggactgg
cttcggatgcagagccaagatgggggccagggccctgaggggggcgctgggcctgtccct
attgaaccacagatctgccaggccacctgtgcggtgatgaaactctcttttgatgaggaa
taccgccgggccatgaatgaacttggtgggctgcaggctgtggcagagttgctgcaggtg
gattatgagatgcataagatgaccaatgaccctctgaacctggccctgcggagatacgcg
ggcatgaccctcaccaacctcaccttcggcgatgttgtcaacaaggccacactgtgtgcc
cggcggggctgtatgcaggctattgtggcccagttggcctcagacagtgaggagctccac
caggtggtgtccagcatccttcgcaacctgtcctggagggcggatattaacagcaagaaa
gtcctgcgggaggtgggcagtatgactgggctcatgcagtgtgcccttcgagccaccaag
gaatccacactgaagagcgtcctcagtgccctatggaacctgtcggcccacagcacagag
aacaaagctgccatatgcttggtggatggagccctgggcttcctggtcagtactctcacc
tataagtgccagagtaactcactagccatcatcgagagtggagggggcatcctccggaat
gtgtccagcctcatcgcgacccgggaggactacaggcaggtgctccgggaccacaactgc
cttcagacgctcctccagcacctgaggtcccacagcctgaccattgtgagtaatgcctgc
gggaccttgtggaacctgtcggctcgtagtccccgtgaccaggagctgctctgggacctg
ggagccgtgagcatgctgcggaacctgatccactccaagcacaagatgatagcgatgggc
agtgcagctgccctgcgcaatctgctcacccaccggcccctcaaatacaaggacacggcg
gctgtcatctcccctggttcttgcatgcccagtctctatgtacgcaagcagaaggccctg
gaggccgagctggatgccaggcacctagcggaagctctggacacaatggagaagcagagc
ctaaagggtcaggttgccaagaagcccccgctgcgccacctcgacagcctggtcaaggac
tatgcttctgattctggctgtttcgacgatgaggatgtgcccgctctggccccaggggtg
gaggtgggtaatccctcagtcctctccatgtttctcaacagttccttcctgcagggccag
gccttgcctcgcatgccagccccacgtcgaggccccgaagcagagagggaggatggcagc
agtggcagaggcagtatggacgccaagaagggggtgatggatgggacggcggcagcggct
gagaaactggccaccaaactgtctgtggctgtggccaagatcgataaactggtggaggac
atctcagccctgcacacctcctcagaggacagcttcagcctcagctcgggtgaccacggg
ctggactggccttcggggcctggggaggtccgggaggccagggcccagtcctgctcaccc
tgccggctccctgaggcaggaaggagggaagggttggggagggctcatccgctcctcagg
ctgaaggcagcttacaccagcctgtccaatgacagcttgaacagcagcagcactagtgat
ggctactgcccccgagaacacatgaagccctccccaagagcctcatttgttgactatcga
gaggagcttcagaggtaccagcagcgccccagccgtctggacctcaagaacattgtggct
acccaacctgacaggagagagcccccatctcaagagtctgctgccccccaggggccagaa
acccaggaggggctgcagaagtcatcaatatttcctggggagtgggctctgaggaaggag
tcagagtggcccaaagaaagggagggcaagcttgccactgactcccacgtgcacaccatc
aaactgtcaccctcatatcagcacgtgcctctgctggagggtatggccaaagtcggtgct
gttccctttcccagcagcggcggtgctccaacagccaggaagcaggcctggctgcccaca
gggaccctgaaaggcactgaagggctgagcaagatccctgagaagctgacagccccagcc
ccaccggctcctgcagcagaaacattacagaagtattccgtggaggacacacccatctgc
ttttcccgatgtagctccctctcctccctctcctcggctgaccatggcatggacgggaga
agccgaagtgaagacaatgagctggacagtgactcttccctggagatcctggaggagccg
gggcccggggagggagaggacgatggggtggaggattggaggcaccgggggactgcttcc
ctgcctgtggccatccctgccccaaggggagaccaggctttcttgtcccaggcccagggg
gatgagggtgcctccccttctcgacaagaagacatgaccccctccagctcctctgagaat
tacatccaggagactccccttgtcatgagccgctgcagctccgtcagctccctgggcagc
tttgagagcccctccattgccagctcgatccagagcgacccctgcagtgagatggtgagt
ggcaccgtgagccccagtgagcttcctgacagcccagggcagaccatgccccccagccgg
agcaagaccccccttccagaacgggagaccagccagttcaacctgcagtgggagaacaat
gtaaagaagttcatggacatcaccgacttcaaggagcgcttccagctgcccccagacctc
gacagcaccatctacttcactgtggagaagccggatgagaacttctcctgcgcctccagc
ctcagcgcgctgcccctccacgagcactacgtgcagaaggatgtggagctcaagctcctg
ccccctttccctgagcgtggaggtggacttcactttgctggccacgaaaagcgggaggag
cctgggcgggaggagcgggtggaaggaacccgtgggggccggcctcgcctggagacccac
tctgaggatgacctcgagatcctgaaagaatgtatcagctcggcaatgccctctcgattc
cgaaaggtcaagacagccctggtgccgggcttgccttcaggcaagaagggactacacgtg
cctgtctacatgctggtgcctgcacatgcccatgctagcatggcagccaggacccctcgg
ccttcccgcagcccatataaagatgaggattccttcacggactcagctgaaggcacgcca
gtcaacttctccagcaccacctcactcagcgacgagacccttcagtatccgcccaaggac
ggccaggggcagcgggctgagaggagggagccaatctctcggcgggttacctccagccat
tctactccaaccaagatggcagctgcctacaagcacagggcagcctgcctaccactatca
agcaggggcactgagccgacccgaggctctctcaaaaatctgcccaacctagaactgact
gttagccggcccaggtcagctcactctgagagggacagccattccaggggggacagtgca
catctaaatgggggtcatggggatgttgcctttcagtctctatgtcacacaacacccact
gaagaggcagtttactgcttctacgagaatgattccgatgatgctcctgaggccccagcc
cggaaggcgccggcaggagcccgggctccaaagaaggagcatagggcaggcaagaaagaa
acggagcccaagaccaaagtggtgccaccgccctccacgcggccccgagcaccccccaaa
tcccagcacaaactgattgcagatgagacgccaccctgctactcattaagctcttctgtg
agctcgctcagtgacctggacctttcagatagggacggtgggcagccacacggcaaaggg
ggcctgtcccacctacaggcccgcaagcctctacataccaagccccccgcactggctcct
ggtcgggacagttctccaagctcccctagcctcaactcagacgaagatttgctacaaagg
tgtattggctccgccatgcccaagagacagcgccatgcagtccgaaaccgcaaggctgag
cgcaagcccaaacaaggggtcccgaaggcaactggcagcaaggagcgaaaggccgagcta
cggagggagctaggcgaggaggtgggctcagaccgagcctcagacctggacagcgtggag
tggcaggctattcaagacggcgccaattccatcgtgacatggctgcaccaggcagcagca
gcagcaacatccttttccagggaaccctcgtctgaatctgactctatcctctcctttgtg
tctggtctgtcagtggggtccaccctgcagcttacccttggaagggaggagcagaagcga
agggggaaggacactggaggagaagtggaaaagaaggaacaaaataaaactgctgatgag
tgcaaaaaaggaggggaggcccggaccctcaaccgccggatgtcccggggcccagaaaag
ccaaacagtgcccagaaacccgtgtctaatctgccagcagtgttccgtggccgaacagtc
atctacatgcccaccctggccaagggtgcccccaagcctcgatctcctccaaagaaaact
gtgcccaagagtgagccccctgccaaacccctcacactcaatcagcagagatcccggagc
ctccaccggccagggaaaatctcagagatgactgagctgacactacccaagaggagtgcc
acaccccctgcccggatggctaagaccccctcctcaggctcttcccaaacctctactcca
tcccagccaccatctaagaagtccccgccctcttcccagataagtaagccagtgccagca
actgggggtaaagcaggcaccaacagccctcaggccagggccccagtgaaggctctgctc
tccagacagcacaaaacccagaaatctcctgtccggattccattcatgcagaagccagtg
aggaagacattcccagtgaggaacaaccagcctgtcccagaggagcagggtgctggaaga
aaggcaggtgggaggctcaatctggtccgtgtggcctcaacccgatccagtggcagtgag
tcagaccgctctggcttccttcgacagctgaccttcatcaaggagtcttccaacctcctc
ctgcgacaccgctccgagaccacaactcccctttctcagaacagctccccacgccgaagt
cggcccggggtcccggccgtcttcctctgttcttctcgctgtgacgagctcaaagcggcc
aaagccgggccccagcctagtcctagagcctctccaggggagcgcctaccccgccggacc
agctcagagagtccttcccgcttacctgtcaagatagctacaccccaacctgaaccattc
aaacgctattcctcatcccctcacatcaatgttgtcaagaggtccggcagtccagccccg
accccaccgcaaagggctgaggctgggggtgggaggaggaggagtgatggagaggccaag
cctctcccccaggtaagtgcaagggagggccacaatgcacagtcaacagccaccaagggt
acatggcggaggattcgggacgaagacataccccatatcctgaagagcacgctcccctcc
actgccctgcctcttgttggcacagtccaggaggatagtccaggtccccagaggaagacc
agtgatgctgtggtccagacagaagacttctcagcctctaaaaccaactccagcacctca
ccaaccctggagaaccgggagccacccaagaatgcagttagcatcccggtcaacagtgtg
caggcccccttcattggcagtgatgtggatgggctgagctccaaggtggctgctgccatc
tccttcacccacgaggggctgacagcccccgcaggaggcttcccctccagccgccacagc
tctcccagccgggctgcccgagttacccccttcaattatatccccagtcccatggtggta
ccagctatgaccgacaaatctgtggagaaagctatcagcctccagggtgaatag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (16)   
   Pfam (16)   
All databases (20)   

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