KEGG   Trichosurus vulpecula (common brushtail): 118844772
Entry
118844772         CDS       T10126                                 
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
  KO
K07293  tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp04014  Ras signaling pathway
tvp04072  Phospholipase D signaling pathway
tvp04148  Efferocytosis
tvp04360  Axon guidance
tvp04625  C-type lectin receptor signaling pathway
tvp04630  JAK-STAT signaling pathway
tvp04650  Natural killer cell mediated cytotoxicity
tvp04660  T cell receptor signaling pathway
tvp04670  Leukocyte transendothelial migration
tvp04722  Neurotrophin signaling pathway
tvp04920  Adipocytokine signaling pathway
tvp04931  Insulin resistance
tvp05168  Herpes simplex virus 1 infection
tvp05205  Proteoglycans in cancer
tvp05208  Chemical carcinogenesis - reactive oxygen species
tvp05211  Renal cell carcinoma
tvp05220  Chronic myeloid leukemia
tvp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:tvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    118844772 (PTPN11)
   04630 JAK-STAT signaling pathway
    118844772 (PTPN11)
   04072 Phospholipase D signaling pathway
    118844772 (PTPN11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    118844772 (PTPN11)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    118844772 (PTPN11)
   04650 Natural killer cell mediated cytotoxicity
    118844772 (PTPN11)
   04660 T cell receptor signaling pathway
    118844772 (PTPN11)
   04670 Leukocyte transendothelial migration
    118844772 (PTPN11)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    118844772 (PTPN11)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    118844772 (PTPN11)
  09158 Development and regeneration
   04360 Axon guidance
    118844772 (PTPN11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    118844772 (PTPN11)
   05208 Chemical carcinogenesis - reactive oxygen species
    118844772 (PTPN11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118844772 (PTPN11)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    118844772 (PTPN11)
   05211 Renal cell carcinoma
    118844772 (PTPN11)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    118844772 (PTPN11)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    118844772 (PTPN11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tvp01009]
    118844772 (PTPN11)
Enzymes [BR:tvp01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     118844772 (PTPN11)
Protein phosphatases and associated proteins [BR:tvp01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    118844772 (PTPN11)
SSDB
Motif
Pfam: Y_phosphatase SH2 SH2_1 PTP-SAK Tc-R-P DSPc PTPlike_phytase Y_phosphatase3 PTP-NADK
Other DBs
NCBI-GeneID: 118844772
NCBI-ProteinID: XP_036608652
Position
1:complement(32940048..33013614)
AA seq 599 aa
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQDLKYD
VGGGEKFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRPENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGAMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPTDPGGVLDFLEEVHHKQESIPDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLADQTSGDQSPLPPCTPTPSCPEYDYSSPPPKGQERCNDFHVKNEFGRFAF
NT seq 1800 nt   +upstreamnt  +downstreamnt
atgacatcccggagatggtttcacccaaatatcactggagtggaggcagaaaatttactg
ctgacacgaggcgttgatggcagcttcttggccaggcccagtaagagtaatccaggggac
ttcacactttctgttaggcggaatggtgctgtcactcacatcaagattcagaacactggt
gactattatgacctgtatggcggggagaagtttgccacactggctgagttagtgcagtat
tatatggagcatcatggacagttgaaagaaaagaacggtgatgttatcgagctcaaatac
ccgctgaactgtgcagatcctacctcggaaaggtggtttcatgggcacctctctgggaaa
gaagcagagaaattactaactgagaaaggaaaacatggaagcttcttggtgcgggaaagc
cagagccacccaggggactttgttctctctgtgcgcacgggggatgacaagggcgagagt
aacgatggcaaatcaaaagtgacacacgtcatgattcgctgccaggatctgaaatatgat
gtcggtggaggagagaagtttgattctttaacagatcttgtggagcattacaagaagaac
cccatggtggaaactctgggtacagtgctccagctcaagcagcccttgaacacgacgcgt
atcaatgctgcagagatcgaaagccgtgtgagagaattaagcaaactagctgagaccacg
gataaagttaaacaaggtttttgggaagaatttgagaccttacaacagcaggaatgcaaa
ctcctatatagccgtaaagagggtcagcggccagaaaataaaaacaaaaacagatataag
aacatcttgccctttgatcacaccagggttgtcctacatgatggggatccaaatgaacca
gtgtcggattatattaatgcgaacattatcatgcctgaatttgagaccaagtgcaacaat
tcaaagcccaaaaagagttatattgcaactcaaggctgtctgcagaacacagtgaatgac
ttctggagaatggtattccaggagaattcacgagttattgtcatgaccacgaaagaagtg
gagagaggcaagagtaaatgtgtcaaatactggccagatgaatatgctctaaaggagtat
ggggctatgcgtgttaggaacgtcaaagaaagtgctgcccatgactatacactaagagag
cttaagctctctaaggttggacaagggaacacggagagaacagtgtggcagtatcatttt
agaacctggcccgatcacggcgtgcccactgaccccgggggtgttctggactttttagaa
gaggtccatcacaagcaggagagcattcctgatgcaggccctgtggtggtgcattgcagt
gctgggatcggcaggacaggaactttcattgtgattgacatccttattgacattatcaga
gaaaaaggtgtggattgtgacattgatgtccccaagaccattcagatggtgagatcccag
agatcagggatggtccagacagaagcccagtacagatttatctacatggccgtgcagcat
tatatcgagacgctacagcgtagaatcgaggaggagcagaaaagcaagagaaaagggcat
gaatatacaaacattaaatattccctagcggaccagacaagtggagatcagagtcctctt
ccaccctgcaccccaactccatcctgtccagaatatgactattcctctccacccccaaaa
ggtcaagaaagatgcaatgactttcatgtgaagaatgaatttggaaggtttgcattctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (9)   
   Pfam (9)   
All databases (15)   

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