KEGG   Trichosurus vulpecula (common brushtail): 118847969
Entry
118847969         CDS       T10126                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp01521  EGFR tyrosine kinase inhibitor resistance
tvp01522  Endocrine resistance
tvp04012  ErbB signaling pathway
tvp04066  HIF-1 signaling pathway
tvp04140  Autophagy - animal
tvp04150  mTOR signaling pathway
tvp04151  PI3K-Akt signaling pathway
tvp04152  AMPK signaling pathway
tvp04211  Longevity regulating pathway
tvp04213  Longevity regulating pathway - multiple species
tvp04350  TGF-beta signaling pathway
tvp04371  Apelin signaling pathway
tvp04666  Fc gamma R-mediated phagocytosis
tvp04714  Thermogenesis
tvp04910  Insulin signaling pathway
tvp04931  Insulin resistance
tvp05163  Human cytomegalovirus infection
tvp05165  Human papillomavirus infection
tvp05170  Human immunodeficiency virus 1 infection
tvp05200  Pathways in cancer
tvp05205  Proteoglycans in cancer
tvp05207  Chemical carcinogenesis - receptor activation
tvp05210  Colorectal cancer
tvp05212  Pancreatic cancer
tvp05221  Acute myeloid leukemia
tvp05224  Breast cancer
tvp05225  Hepatocellular carcinoma
tvp05226  Gastric cancer
tvp05231  Choline metabolism in cancer
tvp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:tvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    118847969 (RPS6KB1)
   04350 TGF-beta signaling pathway
    118847969 (RPS6KB1)
   04371 Apelin signaling pathway
    118847969 (RPS6KB1)
   04066 HIF-1 signaling pathway
    118847969 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    118847969 (RPS6KB1)
   04152 AMPK signaling pathway
    118847969 (RPS6KB1)
   04150 mTOR signaling pathway
    118847969 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118847969 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    118847969 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118847969 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    118847969 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    118847969 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    118847969 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118847969 (RPS6KB1)
   05205 Proteoglycans in cancer
    118847969 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    118847969 (RPS6KB1)
   05231 Choline metabolism in cancer
    118847969 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118847969 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118847969 (RPS6KB1)
   05212 Pancreatic cancer
    118847969 (RPS6KB1)
   05225 Hepatocellular carcinoma
    118847969 (RPS6KB1)
   05226 Gastric cancer
    118847969 (RPS6KB1)
   05221 Acute myeloid leukemia
    118847969 (RPS6KB1)
   05224 Breast cancer
    118847969 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118847969 (RPS6KB1)
   05163 Human cytomegalovirus infection
    118847969 (RPS6KB1)
   05165 Human papillomavirus infection
    118847969 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    118847969 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118847969 (RPS6KB1)
   01522 Endocrine resistance
    118847969 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tvp01001]
    118847969 (RPS6KB1)
Enzymes [BR:tvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     118847969 (RPS6KB1)
Protein kinases [BR:tvp01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   118847969 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 118847969
NCBI-ProteinID: XP_036612570
Position
4:complement(168787428..168818645)
AA seq 534 aa
MRRRRRRDGFYPAPDFRDGEAEAMAGVFDIDLDQPEDAGSEDELEEGGQLSESMDHGGVG
PYEIGMEHCEKFEISETSVNKGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGGDNSKQFYSH
VKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAP
PFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPF
FRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGF
TYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASAATTQTP
VDYPMETSGIEQMDVTVSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1605 nt   +upstreamnt  +downstreamnt
atgaggcggcggcggcggcgggacggattttacccagcgccagacttcagagacggggaa
gctgaggccatggcaggagtttttgacatcgacctggaccagccggaggacgcaggctcc
gaggatgagctggaggaagggggtcaattaagtgaaagcatggaccatggaggagttgga
ccatatgaaattggcatggaacattgtgaaaaatttgaaatctcagaaactagtgtgaac
aaagggccagaaaaaataagaccagaatgttttgagctacttcgagtacttggtaaaggg
ggctatggaaaggttttccaagtacgaaaagtaacaggagcaaatactgggaaaatattt
gccatgaaggtgcttaaaaaggctatgatagtaagaaatgcaaaagatacagctcataca
aaagcagaacggaatatcctcgaggaagtaaagcatcccttcattgtggacttaatttat
gcctttcagactggtggaaaactctacctcatcctggagtatctcagtggaggagaatta
tttatgcagttagaaagagagggaatatttatggaagatacagcttgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaagggatcatctacagggacctgaag
ccggaaaatatcatgcttaatcaccaaggtggagataacagtaaacaattctatagtcat
gtgaaattgacggactttggactatgcaaagaatccattcatgatggaacagtcacacac
acgttctgtggaacaatagaatacatggctcctgaaatcttgatgagaagtggccataat
cgtgctgtggactggtggagtttgggggcattaatgtatgacatgctgactggagcaccc
ccatttactggggagaacagaaagaagaccattgacaaaatcctcaaatgtaaacttaat
ttgcctccctacctcacacaagaagccagagatctgcttaaaaagctgctaaagagaaat
gctgcttcgcgtcttggagctggtcctggggatgctggagaagttcaggctcatcctttc
ttcagacacattaactgggaagaacttctggctcggaaggtggagcccccctttaaacct
cttttgcaatctgaagaggatgtgagccagtttgattcaaagtttacacgtcagacacct
gttgacagcccagatgactcaactctcagtgaaagtgccaaccaggtctttctgggtttt
acatatgtggctccatctgtacttgaaagcgtgaaagaaaaattttcatttgaaccaaaa
atccgatcacctcgaagatttatcggcagccctcggacgcctgtcagcccagtcaaattt
tctcctggggatttctggggaagaggtgcttcagccagtgcagcaactactcagacacct
gtggattatcccatggaaacgagtggaatagaacaaatggatgtgacggtgagtggagaa
gcatcagcaccacttccaatccgacagcctaactctgggccatataaaaaacaagctttt
cctatgatctccaaacggccagaacacttgcgtatgaatctatga

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