KEGG   Trichosurus vulpecula (common brushtail): 118853358
Entry
118853358         CDS       T10126                                 
Symbol
HMGCR
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
  KO
K00021  hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp00900  Terpenoid backbone biosynthesis
tvp01100  Metabolic pathways
tvp04152  AMPK signaling pathway
tvp04976  Bile secretion
Module
tvp_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:tvp00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    118853358 (HMGCR)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    118853358 (HMGCR)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    118853358 (HMGCR)
Enzymes [BR:tvp01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.34  hydroxymethylglutaryl-CoA reductase (NADPH)
     118853358 (HMGCR)
SSDB
Motif
Pfam: HMG-CoA_red Sterol-sensing Patched
Other DBs
NCBI-GeneID: 118853358
NCBI-ProteinID: XP_036619275
Position
1:complement(441733438..441761073)
AA seq 884 aa
MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNDKICGWNYECPKFEEDVLSS
DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG
LNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG
VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR
VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSSQNSTAENSKVALGLDENVSKR
IEPNVSLWQFYLSKMISMDIEQMITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVMI
QKKAPDTCCRREPVLARNKQKFSEMEEESGHNKERKAEVIKPLLAETETSKVTFVLGNSA
AHPTSSNTEPEIELPTEPRPNEECLQILENIEKGAKFLSDAEIIRLVNAKHIPAYKLETL
METHERGVSIRRQMLSKKLPEPSSLEYLPYRDYNYSLVMGACCENVIGYMPVPVGVAGPL
SLDGKEFQVPMATTEGCLVASTNRGCRAICLGGGASSCVLADGMTRGPVVRFPSACDSAK
MKTWLESPEGFKIIKEAFDSTSRFARLQKVHISLAGRNAYIRFQSRTGDAMGMNMISKGT
EKALAKLHEVFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTT
TEALVEVNISKNLVGSAMAGSIGGYNAHAANIVTAIFIACGQDAAQNVCSSNCITLMEAT
GPLNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAKIVCG
TVMAGELSLMAALAAGHLVKSHMIHNRSKVNLQNLQGTCTKKVA
NT seq 2655 nt   +upstreamnt  +downstreamnt
atgttgtcaagactcttccgaatgcatggcctctttgtggcatcccatccttgggaagtc
atagtgggcactgtgactcttaccatctgcatgatgtccatgaacatgtttactggtaat
gacaaaatctgtggctggaattatgaatgtccaaagtttgaagaagatgttttaagcagt
gatattatcattctgacaatcacacgatgcatagcaatcctgtatatttactttcagttc
cagaatctaagacagcttggatcaaaatatattttgggcatcgccggcctttttaccatc
ttctcaagctttgtcttcagcacagttgttattcatttcttagataaagagttgacgggc
ctgaatgaagctctgcccttttttctgctcttgattgacctttcccgagccagtgcttta
gcaaagtttgccctcagttctaactcacaggatgaagtaagagaaaacattgcccgtgga
atggcaatcttaggcccaactttcacactcgatgcccttgtcgaatgtcttgtgattggt
gttggtaccatgtctggtgttcgacaacttgaaattatgtgctgctttggttgcatgtca
gtccttgccaattactttgtgttcatgacattctttccagcttgtgtatctttggtatta
gagctgtctcgggaaagtcgtgaaggtcgtccaatatggcaactcagtcattttgcccgt
gttttagaagaagaagaaaataaaccaaatcctgtaactcagcgggtcaagatgattatg
tctctaggcttggttcttgttcatgctcatagtcgctggatagctgatccatcatctcag
aacagtaccgccgaaaattctaaggttgctttaggactggatgaaaatgtgtccaaaaga
attgaacctaatgtttctctctggcagttttatctttctaagatgatcagtatggacatt
gaacaaatgatcacccttagtttagctctccttctggctgtcaagtacatcttctttgaa
caggcagaaacagagtctacactgtcattaaaaaaccccatcacgtctcctgtgatgatt
caaaagaaggctccagacacctgttgtagacgggaacctgtgttggccagaaataagcag
aaattcagtgaaatggaagaagaatctgggcataacaaggagagaaaagctgaagttata
aagcccttattggcagaaactgaaacatcaaaggttacatttgttttgggtaactcagct
gcacatccaacatcatcgaacactgagcctgaaatcgaactacccactgaaccacgtcct
aatgaagaatgtctccagatacttgaaaatatagagaaaggtgcaaaattcctcagtgat
gctgagatcatcagattagtcaatgctaagcatattccagcttataaattggaaactttg
atggaaacccatgagcgaggtgtgtctattcgccgacaaatgttgtctaagaagcttcct
gaaccctcttcattagagtatttaccatacagggattataattattctttggtgatgggg
gcatgctgtgagaatgttattggatacatgcctgttcccgttggagtagccgggcccctc
tctctggatggcaaagaattccaggtcccaatggccacaactgaaggctgtcttgtagcc
agtaccaacaggggttgtagagcaatatgtcttggtggaggagcaagtagctgtgttctg
gcagatgggatgactcgagggccagtagtaaggtttcccagcgcatgtgactctgcaaag
atgaagacttggcttgaaagtcctgaaggctttaagataataaaggaagcgtttgacagc
accagcaggtttgcgcgtcttcagaaagttcacattagtctggctggtcggaatgcctat
atccgtttccaatccaggacaggggatgccatgggaatgaatatgatttcaaagggaaca
gagaaagcacttgcaaaacttcatgaagtttttcctgaaatgcaaatcctagccgttagc
ggtaactactgtacagacaaaaaacctgctgctataaattggatagagggaagaggaaaa
tctgttgtttgtgaagctgtcattccagcaaaggttgtcagagaagtattaaaaaccact
acagaagctttggttgaagttaacataagcaagaatttggtgggctcagccatggctggt
agcataggaggctataatgcacatgcagccaatattgtaactgccatcttcattgcttgt
gggcaggatgcagctcagaatgtgtgcagctctaattgtatcactcttatggaagcaact
ggccccttaaatgaagacctgtatatcagctgtactatgccatccatagaaataggaact
gttggtggaggaaccaacctgctaccacagcaggcctgtctgcagatgctaggtgttcaa
ggagcatgcaaagacaaccctggtgaaaatgcccgtcagctcgcaaaaatcgtgtgtggt
acagttatggccggggagttatcactgatggctgcgttggctgcaggacacctagtcaaa
agccacatgatccacaacaggtcaaaagtaaacctacaaaatctccaaggaacctgcacc
aagaaagtggcttga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (7)   

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