KEGG   Trichosurus vulpecula (common brushtail): 118854947
Entry
118854947         CDS       T10126                                 
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8
  KO
K08048  adenylate cyclase 8 [EC:4.6.1.1]
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp00230  Purine metabolism
tvp01100  Metabolic pathways
tvp01522  Endocrine resistance
tvp04015  Rap1 signaling pathway
tvp04020  Calcium signaling pathway
tvp04022  cGMP-PKG signaling pathway
tvp04024  cAMP signaling pathway
tvp04062  Chemokine signaling pathway
tvp04072  Phospholipase D signaling pathway
tvp04081  Hormone signaling
tvp04082  Neuroactive ligand signaling
tvp04114  Oocyte meiosis
tvp04211  Longevity regulating pathway
tvp04213  Longevity regulating pathway - multiple species
tvp04261  Adrenergic signaling in cardiomyocytes
tvp04270  Vascular smooth muscle contraction
tvp04371  Apelin signaling pathway
tvp04540  Gap junction
tvp04611  Platelet activation
tvp04713  Circadian entrainment
tvp04714  Thermogenesis
tvp04720  Long-term potentiation
tvp04723  Retrograde endocannabinoid signaling
tvp04724  Glutamatergic synapse
tvp04725  Cholinergic synapse
tvp04727  GABAergic synapse
tvp04742  Taste transduction
tvp04750  Inflammatory mediator regulation of TRP channels
tvp04911  Insulin secretion
tvp04912  GnRH signaling pathway
tvp04913  Ovarian steroidogenesis
tvp04914  Progesterone-mediated oocyte maturation
tvp04915  Estrogen signaling pathway
tvp04916  Melanogenesis
tvp04918  Thyroid hormone synthesis
tvp04921  Oxytocin signaling pathway
tvp04923  Regulation of lipolysis in adipocytes
tvp04925  Aldosterone synthesis and secretion
tvp04926  Relaxin signaling pathway
tvp04927  Cortisol synthesis and secretion
tvp04928  Parathyroid hormone synthesis, secretion and action
tvp04934  Cushing syndrome
tvp04935  Growth hormone synthesis, secretion and action
tvp04970  Salivary secretion
tvp04971  Gastric acid secretion
tvp04972  Pancreatic secretion
tvp04976  Bile secretion
tvp05032  Morphine addiction
tvp05163  Human cytomegalovirus infection
tvp05166  Human T-cell leukemia virus 1 infection
tvp05200  Pathways in cancer
tvp05207  Chemical carcinogenesis - receptor activation
tvp05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tvp00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    118854947 (ADCY8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    118854947 (ADCY8)
   04371 Apelin signaling pathway
    118854947 (ADCY8)
   04020 Calcium signaling pathway
    118854947 (ADCY8)
   04072 Phospholipase D signaling pathway
    118854947 (ADCY8)
   04024 cAMP signaling pathway
    118854947 (ADCY8)
   04022 cGMP-PKG signaling pathway
    118854947 (ADCY8)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    118854947 (ADCY8)
   04081 Hormone signaling
    118854947 (ADCY8)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    118854947 (ADCY8)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    118854947 (ADCY8)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118854947 (ADCY8)
   04062 Chemokine signaling pathway
    118854947 (ADCY8)
  09152 Endocrine system
   04911 Insulin secretion
    118854947 (ADCY8)
   04923 Regulation of lipolysis in adipocytes
    118854947 (ADCY8)
   04912 GnRH signaling pathway
    118854947 (ADCY8)
   04913 Ovarian steroidogenesis
    118854947 (ADCY8)
   04915 Estrogen signaling pathway
    118854947 (ADCY8)
   04914 Progesterone-mediated oocyte maturation
    118854947 (ADCY8)
   04921 Oxytocin signaling pathway
    118854947 (ADCY8)
   04926 Relaxin signaling pathway
    118854947 (ADCY8)
   04935 Growth hormone synthesis, secretion and action
    118854947 (ADCY8)
   04918 Thyroid hormone synthesis
    118854947 (ADCY8)
   04928 Parathyroid hormone synthesis, secretion and action
    118854947 (ADCY8)
   04916 Melanogenesis
    118854947 (ADCY8)
   04925 Aldosterone synthesis and secretion
    118854947 (ADCY8)
   04927 Cortisol synthesis and secretion
    118854947 (ADCY8)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118854947 (ADCY8)
   04270 Vascular smooth muscle contraction
    118854947 (ADCY8)
  09154 Digestive system
   04970 Salivary secretion
    118854947 (ADCY8)
   04971 Gastric acid secretion
    118854947 (ADCY8)
   04972 Pancreatic secretion
    118854947 (ADCY8)
   04976 Bile secretion
    118854947 (ADCY8)
  09156 Nervous system
   04724 Glutamatergic synapse
    118854947 (ADCY8)
   04727 GABAergic synapse
    118854947 (ADCY8)
   04725 Cholinergic synapse
    118854947 (ADCY8)
   04720 Long-term potentiation
    118854947 (ADCY8)
   04723 Retrograde endocannabinoid signaling
    118854947 (ADCY8)
  09157 Sensory system
   04742 Taste transduction
    118854947 (ADCY8)
   04750 Inflammatory mediator regulation of TRP channels
    118854947 (ADCY8)
  09149 Aging
   04211 Longevity regulating pathway
    118854947 (ADCY8)
   04213 Longevity regulating pathway - multiple species
    118854947 (ADCY8)
  09159 Environmental adaptation
   04713 Circadian entrainment
    118854947 (ADCY8)
   04714 Thermogenesis
    118854947 (ADCY8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118854947 (ADCY8)
   05207 Chemical carcinogenesis - receptor activation
    118854947 (ADCY8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118854947 (ADCY8)
   05163 Human cytomegalovirus infection
    118854947 (ADCY8)
  09165 Substance dependence
   05032 Morphine addiction
    118854947 (ADCY8)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    118854947 (ADCY8)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118854947 (ADCY8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118854947 (ADCY8)
Enzymes [BR:tvp01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     118854947 (ADCY8)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD
Other DBs
NCBI-GeneID: 118854947
NCBI-ProteinID: XP_036621017
Position
1:105485991..105887426
AA seq 1253 aa
MELSDVRCLSSTEELYTINPTPPASGGSGGSCSGAGGGSRPQRLLWQTAVRHITEQRFIH
QSGVCGGNGKTSDPGGPNHHAPHLQQAPALPLYPLGQPGRLGSAGKGGHNNGGGPTKVFP
ERRGSSGDLGFLHLDCAPSNSDFFLNWGYTYRGVIFPTLRNSFKSRDLERLYQRYFLGQR
RKSEVVMNILDVLTKLTLLVLHLTLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTS
YTYLQYSGLVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLV
TSLVQIVLELIIPRLAVNSINQIVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVE
ARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHKIYIHRYENVSILFA
DVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDH
AHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIAN
KLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLTLP
EDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQAL
HVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVC
AFIVLLFITAIQSLLPSSRMMPMVIQFSLLIMLHSALVLITTAEDYKCLPLVLRKTCCWI
NETYLARNVIIFASILINFLGAILNILWCDFDKSVPLKNQTSNSSAVFTDICSYPEYFVF
TGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYSLLMETIYASLFLHYDNFNHNGEDFLGTK
EASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSH
VARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADF
DELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALNESIQEIN
KHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYL
ILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPLILPPRKLPGQYSLAAVVLG
LVQSLNRQRQKQILNENNNPGIIKAHYNRRTLLTASGPEPAAQAEGVDKSDLP
NT seq 3762 nt   +upstreamnt  +downstreamnt
atggagttatccgatgtgcgctgcttgagcagcacggaagaactctacaccattaacccg
acacccccggccagcggcggcagcggggggagctgcagcggtgccggcggtggctcgcga
ccccagaggctgctgtggcagaccgcggtgcggcacatcaccgagcagcgcttcatccac
cagagcggcgtctgcggcgggaacggcaagaccagcgaccctggcggccccaaccaccac
gcgccccacctccagcaagccccagccctccccctctaccctttgggtcagcccgggcgt
ctgggctcggccgggaaaggcggtcacaacaacgggggtggccccaccaaagtcttcccg
gagcggaggggcagcagcggtgacctgggtttcctgcaccttgactgcgctcccagtaac
tcggatttttttctcaactggggttacacctaccgaggggtgatcttccccaccctacgg
aactcctttaagtcccgggacctggagcgcctctaccagcgctatttcctgggacagcgg
cgcaagtccgaggtggtcatgaacatcttggacgtgttgaccaaactaaccttgctcgtg
ctccacctgaccctggcgtcggcccccatggaccccctcaagggcatccttctgggtttc
tttacaggcatcgaggtggtcatctgtgctttggtggtggtcaggaaggacaccacttcc
tacacatacctacagtacagcgggctggtgacctgggtggccatgacgactcagatcctg
gccgcaggtctgggctacgggctcctaggggatgggattggctatgtgctcttcactctc
ttcgccacctacagcatgctgccgctgcccctcacctgggccatccttgcggggctggta
acatctctagtgcagatcgtcctggaactaatcatcccccggttggcggtgaattccatc
aaccagatagtggctcaggcggtcttgttcatgtgcatgaacacagcaggaatcttcatt
agctacctgtcagacagagcccaacgtcaagccttcctggaaacccgaagatgtgtggaa
gcaaggttgagactagaaacggagaatcagagacaggaaagactggtactttctgtcctg
cctcggtttgtcgtcctagagatgatcaatgatatgaccaacgtggaagacgagcatttg
cagcaccagttccacaagatctacatccatcgctatgagaatgtcagtattctttttgca
gatgttaaaggatttaccaacctttccacgaccttgtcagcacaggagctggtcaggatg
ttgaatgaactctttgccagatttgatcgactggcccatgaacatcattgtcttcgaatt
aagatattgggggactgttactattgtgtgtctggactccctgaacctcgtcaggaccat
gcccactgctgtgttgaaatggggctcagtatgatcaagaccatcaggtatgttaggtca
aggacaaagcatgacgttgacatgcgcataggcatccattctggatcagtcctctgtgga
gtgttgggtctccggaagtggcagtttgatgtttggtcctgggacgtggacatcgcaaat
aagctagaatcaggtggaatccctgggaggattcacatctccaaagccacactggactgc
ctcaatggggattataacgttgaagaagggcacggtaaagaacgaaatgagttcttgaga
aaacataacatagagacctatttaataaagcagcccgaggaaagtctcttgactttgccc
gaagacattgtaaaggagtcagtcagctcctcagataggagaaacagtggggccacattt
acagaaggatcctggagccctgaactcccatttgataacattgtggggaaacagaatact
ctggctgccctaacaagaaattcaataaatctgcttccaaaccatcttgcacaagctttg
catgtccagtctgggcctgaggaaattaacaagagaatagagcacaccatcgacttacgg
agtggcgataaattgagaagagagcatatcaagcctttctcactgatgtttaaagactcc
agcctggagcataagtattctcaaatgagggatgaagtattcaaatcaaacttggtctgt
gcatttatcgtacttctctttatcaccgcaatccaaagtttgcttccttcttcaaggatg
atgccaatggtcattcaattttctctcttgatcatgctgcactcggcccttgttcttatc
accacagcagaggattataagtgtttaccacttgtgctgcggaaaacttgctgttggatt
aatgagacctatctggccagaaatgttatcatctttgcctccatcttgattaatttcctt
ggtgccatcttaaatattctgtggtgtgattttgacaagtcagtacccttgaagaaccag
acttccaattcctcggctgtgtttacagatatctgctcatacccagagtacttcgtcttc
acgggtgtgttggccatggtgacctgtgcagttttcctccgacttaactctgtcctgaag
ctggctgtgttgctgattatgattgcaatctattctctactgatggagaccatttatgct
tcgctctttctgcactatgacaactttaatcacaatggagaggatttcctgggaaccaag
gaggcctctctgcttttgatggccatgtttctccttgctgtgttttaccatggacagcag
ctagaatacacagctcgtctggacttcctctggcgtgttcaggccaaagaggagatcaat
gagatgaaagaactgagggagcacaatgagaacatgcttcgtaacattctgcccagtcac
gtggcccgacatttcttagagaaggaccgagataacgaggagctgtattcccaatcctat
gatgctgttggtgtgatgtttgcctccatcccaggatttgctgatttttattctcaaacc
gaaatgaataaccaaggagtggaatgtcttcgcttgctgaatgaaatcatcgctgacttt
gatgagttacttggggaagaccgatttcaagatatcgaaaaaattaagacgatcggcagc
acttacatggcagtatcaggcttatcacctgagaaacagcaatgcgaagataagtgggga
cacttatgtgctctggctgacttctctctcgccctgaacgaaagcatacaggagatcaac
aagcattcatttaataattttgagctccgcattggtatcagccatggatctgtggtagca
ggagttattggcgccaagaagccacagtatgatatctggggcaaaaccgtcaacctggca
agtcgtatggatagcacaggcgtcagtggccggatccaagtgccggaggagacatatctc
atcctgaaggaccaaggctttgcttttgactacagaggagagatttatgtcaaaggcatc
agtgaacaggaaggaaaaatcaaaacatattttcttctgggaagagtacaacccaatcca
ttaatcttaccaccaagaaaactgcctggacagtactccttggcagctgttgtcctggga
ctggttcaatcactaaacaggcaaagacagaagcaaatactcaatgagaacaacaacccc
ggcattataaaggctcattataaccgacggactttgttgactgccagtggacctgaacca
gcagcccaagcagaaggcgttgataaatctgacttgccataa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (8)   

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