KEGG   Ursus maritimus (polar bear): 103665538
Entry
103665538         CDS       T03271                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr01522  Endocrine resistance
umr04010  MAPK signaling pathway
umr04015  Rap1 signaling pathway
umr04068  FoxO signaling pathway
umr04071  Sphingolipid signaling pathway
umr04114  Oocyte meiosis
umr04148  Efferocytosis
umr04218  Cellular senescence
umr04261  Adrenergic signaling in cardiomyocytes
umr04370  VEGF signaling pathway
umr04380  Osteoclast differentiation
umr04517  IgSF CAM signaling
umr04519  Cadherin signaling
umr04550  Signaling pathways regulating pluripotency of stem cells
umr04611  Platelet activation
umr04613  Neutrophil extracellular trap formation
umr04620  Toll-like receptor signaling pathway
umr04621  NOD-like receptor signaling pathway
umr04622  RIG-I-like receptor signaling pathway
umr04625  C-type lectin receptor signaling pathway
umr04657  IL-17 signaling pathway
umr04658  Th1 and Th2 cell differentiation
umr04659  Th17 cell differentiation
umr04660  T cell receptor signaling pathway
umr04664  Fc epsilon RI signaling pathway
umr04668  TNF signaling pathway
umr04670  Leukocyte transendothelial migration
umr04714  Thermogenesis
umr04722  Neurotrophin signaling pathway
umr04723  Retrograde endocannabinoid signaling
umr04728  Dopaminergic synapse
umr04750  Inflammatory mediator regulation of TRP channels
umr04912  GnRH signaling pathway
umr04914  Progesterone-mediated oocyte maturation
umr04917  Prolactin signaling pathway
umr04926  Relaxin signaling pathway
umr04932  Non-alcoholic fatty liver disease
umr04933  AGE-RAGE signaling pathway in diabetic complications
umr04935  Growth hormone synthesis, secretion and action
umr04936  Alcoholic liver disease
umr05014  Amyotrophic lateral sclerosis
umr05020  Prion disease
umr05022  Pathways of neurodegeneration - multiple diseases
umr05132  Salmonella infection
umr05133  Pertussis
umr05135  Yersinia infection
umr05140  Leishmaniasis
umr05142  Chagas disease
umr05145  Toxoplasmosis
umr05152  Tuberculosis
umr05161  Hepatitis B
umr05163  Human cytomegalovirus infection
umr05167  Kaposi sarcoma-associated herpesvirus infection
umr05169  Epstein-Barr virus infection
umr05170  Human immunodeficiency virus 1 infection
umr05171  Coronavirus disease
umr05205  Proteoglycans in cancer
umr05208  Chemical carcinogenesis - reactive oxygen species
umr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
umr05415  Diabetic cardiomyopathy
umr05417  Lipid and atherosclerosis
umr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103665538 (MAPK13)
   04015 Rap1 signaling pathway
    103665538 (MAPK13)
   04370 VEGF signaling pathway
    103665538 (MAPK13)
   04668 TNF signaling pathway
    103665538 (MAPK13)
   04068 FoxO signaling pathway
    103665538 (MAPK13)
   04071 Sphingolipid signaling pathway
    103665538 (MAPK13)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    103665538 (MAPK13)
   04519 Cadherin signaling
    103665538 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103665538 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103665538 (MAPK13)
   04218 Cellular senescence
    103665538 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103665538 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103665538 (MAPK13)
   04613 Neutrophil extracellular trap formation
    103665538 (MAPK13)
   04620 Toll-like receptor signaling pathway
    103665538 (MAPK13)
   04621 NOD-like receptor signaling pathway
    103665538 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    103665538 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    103665538 (MAPK13)
   04660 T cell receptor signaling pathway
    103665538 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    103665538 (MAPK13)
   04659 Th17 cell differentiation
    103665538 (MAPK13)
   04657 IL-17 signaling pathway
    103665538 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    103665538 (MAPK13)
   04670 Leukocyte transendothelial migration
    103665538 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103665538 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    103665538 (MAPK13)
   04917 Prolactin signaling pathway
    103665538 (MAPK13)
   04926 Relaxin signaling pathway
    103665538 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    103665538 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103665538 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    103665538 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    103665538 (MAPK13)
   04722 Neurotrophin signaling pathway
    103665538 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103665538 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103665538 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    103665538 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103665538 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    103665538 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103665538 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103665538 (MAPK13)
   05161 Hepatitis B
    103665538 (MAPK13)
   05171 Coronavirus disease
    103665538 (MAPK13)
   05163 Human cytomegalovirus infection
    103665538 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103665538 (MAPK13)
   05169 Epstein-Barr virus infection
    103665538 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103665538 (MAPK13)
   05135 Yersinia infection
    103665538 (MAPK13)
   05133 Pertussis
    103665538 (MAPK13)
   05152 Tuberculosis
    103665538 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103665538 (MAPK13)
   05140 Leishmaniasis
    103665538 (MAPK13)
   05142 Chagas disease
    103665538 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103665538 (MAPK13)
   05020 Prion disease
    103665538 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    103665538 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103665538 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    103665538 (MAPK13)
   05415 Diabetic cardiomyopathy
    103665538 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103665538 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    103665538 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103665538 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103665538 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:umr01001]
    103665538 (MAPK13)
Enzymes [BR:umr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103665538 (MAPK13)
Protein kinases [BR:umr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103665538 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 RIO1 APH Kdo Kinase-like
Other DBs
NCBI-GeneID: 103665538
NCBI-ProteinID: XP_040500632
UniProt: A0A8M1H0L7
Position
Unknown
AA seq 366 aa
MSFTRKKGFYKQDVNKTSWELPKTYVSPTHIGSGAYGAVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELRLLKHMQHENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIMGM
EFSEDKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLSQILKVTG
VPGAEFVQKLHDKAAKSYIQALPQSPKKDFSQLFPRASPQAIDVLEKMLELDVDKRLTAS
QALAHPFFELFRDPEEETEAPQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPVARKDSRRR
SGMKLQ
NT seq 1101 nt   +upstreamnt  +downstreamnt
atgagcttcacccggaaaaagggcttctacaagcaggacgtcaacaagaccagctgggag
ctgcccaagacctacgtgtccccgacgcacataggcagcggggcttatggcgccgtgtgc
tccgccatcgacaagcggtcaggggagaaggtggccatcaagaagctgagccggcccttc
cagtccgagatcttcgccaagcgggcctaccgagagctgcggctgctgaagcacatgcag
catgagaacgtcatcgggctcctggatgtcttcaccccagcctcctccctgcgcagcttc
catgacttctacctggtgatgcccttcatgcagacggacctgcagaagatcatggggatg
gagttcagcgaggacaagatccagtacctggtgtatcagatgcttaaggggctcaagtac
atccactcagctggggtcgtccacagggacctaaagccgggcaacctggctgtgaacgag
gactgcgagctgaagatcttggatttcggcctggcccggcacgcggacgcggagatgacg
ggctacgtggtgacccgctggtaccgggcccccgaggtgatcctcagctggatgcactac
aaccagaccgtggacatctggtctgtgggctgtatcatggcagagatgctgacggggaag
actctgttcaaggggaaagattacctggaccagctgtcccagatcctgaaagtgaccggg
gtgccgggcgcagagtttgtgcagaagttgcacgacaaagcagccaaatcctacatccag
gccctgccacagagccccaagaaggatttctctcagctcttcccgcgcgccagcccccag
gccatagacgtgctggagaagatgctggagctggacgtggacaagcgcctgacggcctcg
caggccctcgcgcaccccttctttgaactcttccgagacccggaggaggagacagaggcc
ccgcagccttttgatgattccctggaacatgagaaactcacagtggatgaatggaagcag
cacatctacaaggagatcgtgaacttcagccccgttgcccggaaggactcacggcgccgg
agcggcatgaagctgcagtga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (13)   

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