ID A0A024HQ86_PSEKB Unreviewed; 638 AA.
AC A0A024HQ86;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 02-APR-2025, entry version 44.
DE SubName: Full=Esterase estA {ECO:0000313|EMBL:CDF86717.1};
DE EC=3.1.1.1 {ECO:0000313|EMBL:CDF86717.1};
GN Name=esta3 {ECO:0000313|EMBL:CDF86717.1};
GN ORFNames=PKB_5405 {ECO:0000313|EMBL:CDF86717.1};
OS Pseudomonas knackmussii (strain DSM 6978 / CCUG 54928 / LMG 23759 / B13).
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Pseudomonadales; Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1301098 {ECO:0000313|EMBL:CDF86717.1, ECO:0000313|Proteomes:UP000025241};
RN [1] {ECO:0000313|EMBL:CDF86717.1, ECO:0000313|Proteomes:UP000025241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B13 {ECO:0000313|EMBL:CDF86717.1,
RC ECO:0000313|Proteomes:UP000025241};
RA Linke B.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDF86717.1, ECO:0000313|Proteomes:UP000025241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B13 {ECO:0000313|EMBL:CDF86717.1,
RC ECO:0000313|Proteomes:UP000025241};
RA Miyazaki R., Bertelli C., Falquet L., Robinson-Rechavi M., Gharib W.,
RA Roy S., Van der Meer J.R.;
RT "Genome sequence of the 3-chlorobenzoate degrading bacterium Pseudomonas
RT knackmussii B13 shows multiple evidence for horizontal gene transfer.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000256|ARBA:ARBA00008668}.
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DR EMBL; HG322950; CDF86717.1; -; Genomic_DNA.
DR RefSeq; WP_043256044.1; NZ_HG322950.1.
DR AlphaFoldDB; A0A024HQ86; -.
DR STRING; 1301098.PKB_5405; -.
DR KEGG; pkc:PKB_5405; -.
DR PATRIC; fig|1301098.3.peg.5393; -.
DR eggNOG; COG3240; Bacteria.
DR eggNOG; COG4625; Bacteria.
DR HOGENOM; CLU_023098_5_0_6; -.
DR OrthoDB; 5292073at2; -.
DR Proteomes; UP000025241; Chromosome.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR GO; GO:0106435; F:carboxylesterase activity; IEA:UniProtKB-EC.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd01847; Triacylglycerol_lipase_like; 1.
DR Gene3D; 2.40.128.130; Autotransporter beta-domain; 1.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR048099; Esterase_EstP/EstA.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR051058; GDSL_Est/Lipase.
DR InterPro; IPR017186; Lipase_autotranspt_EstA.
DR InterPro; IPR008265; Lipase_GDSL_AS.
DR InterPro; IPR006315; OM_autotransptr_brl_dom.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR NCBIfam; TIGR01414; autotrans_barl; 1.
DR NCBIfam; NF041609; esterase_EstP; 1.
DR PANTHER; PTHR45648; GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700); 1.
DR PANTHER; PTHR45648:SF22; GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700); 1.
DR Pfam; PF03797; Autotransporter; 1.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR PIRSF; PIRSF037375; Autotrns_EstA; 1.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; Autotransporter; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
DR PROSITE; PS01098; LIPASE_GDSL_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:CDF86717.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000025241};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..638
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001533571"
FT DOMAIN 359..638
FT /note="Autotransporter"
FT /evidence="ECO:0000259|PROSITE:PS51208"
FT ACT_SITE 37
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR037375-1"
FT ACT_SITE 303
FT /evidence="ECO:0000256|PIRSR:PIRSR037375-1"
FT ACT_SITE 306
FT /evidence="ECO:0000256|PIRSR:PIRSR037375-1"
SQ SEQUENCE 638 AA; 67879 MW; AABCEDC2AEBEB5FD CRC64;
MIKQVLTPLA AACLLGIAGQ ASASPSPYST MVIFGDSLSD AGQFPDAGGP AGASTRFTNR
VGPTYLDGSG EIFGPTAAMI IGGRLGVSAA DRGPSTSLVN AANGLPDGNN WAVGGYRTDQ
IYDSITAPGG SVVSANGQTR TRDGYLVGRR ADPNALYYLT GGGNDFLQLR ITNDPTARAA
AGRLVDSVNA LNQAGARYIM VWLLPDLGLT PATNGTALQS FGTQLSGIFN EELVSELSAS
GANVIPLNIP KMLGEVLADP GAYGLATGQN LVGTCFSGNS CPENATYGRH GASPDPTKLI
FNDGVHPTIA GQTIIADYAY SILSAPWEAS LLPEMALGTL NTFQPPRPSQ WLADWGEWQR
VGQWRGFISG GGQHLDYDDQ DSAANGDGFG YNLNLGGSYR LDEAWRIGVA AGIYGQKLEA
GPEDSDYKLN SYLGSLFAQF QQDRWWADAA VSAGYLDYAD ANRKFAIYKR TVEEKADTNG
NLIAFSGRLG YDIAQGGENW HLSPFVSADW ARVKVDGYTE GSGDAEAISF DEQNRYSRRL
GAGLQGKYDL SAETRLFGEV GVEREYADDT QNIGMNLTSL STLDFTLQGY TPQSHMQHAT
LGFDQKLTPE LSLRGGYSAH RSDDNLQQGV NLALSLDF
//
