ID A0A085U984_YERRU Unreviewed; 720 AA.
AC A0A085U984;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 18-JUN-2025, entry version 57.
DE RecName: Full=ornithine decarboxylase {ECO:0000256|ARBA:ARBA00034138};
DE EC=4.1.1.17 {ECO:0000256|ARBA:ARBA00034138};
GN Name=speF {ECO:0000313|EMBL:SUQ00352.1};
GN ORFNames=CSF007_2345 {ECO:0000313|EMBL:CEK26252.1}, NCTC10476_01635
GN {ECO:0000313|EMBL:SUQ00352.1};
OS Yersinia ruckeri.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Enterobacterales; Yersiniaceae; Yersinia.
OX NCBI_TaxID=29486 {ECO:0000313|EMBL:CEK26252.1};
RN [1] {ECO:0000313|EMBL:CEK26252.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CSF007-82 {ECO:0000313|EMBL:CEK26252.1};
RA Nelson M.C., LaPatra S.E., Welch T.J., Graf J.;
RT "Complete Genome Sequence of Yersinia ruckeri Strain CSF007-82, Etiologic
RT Agent of Red Mouth Disease in Salmonid Fish.";
RL Genome Announc. 3:1-2(2015).
RN [2] {ECO:0000313|EMBL:SUQ00352.1, ECO:0000313|Proteomes:UP000255169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10476 {ECO:0000313|EMBL:SUQ00352.1,
RC ECO:0000313|Proteomes:UP000255169};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-ornithine + H(+) = putrescine + CO2; Xref=Rhea:RHEA:22964,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:46911,
CC ChEBI:CHEBI:326268; EC=4.1.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00049127};
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
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DR EMBL; LN681231; CEK26252.1; -; Genomic_DNA.
DR EMBL; UHJG01000001; SUQ00352.1; -; Genomic_DNA.
DR RefSeq; WP_004720425.1; NZ_VDHI01000017.1.
DR AlphaFoldDB; A0A085U984; -.
DR STRING; 29486.UGYR_12145; -.
DR GeneID; 66878239; -.
DR KEGG; yrb:UGYR_12145; -.
DR PATRIC; fig|29486.44.peg.828; -.
DR eggNOG; COG1982; Bacteria.
DR OrthoDB; 9761189at2; -.
DR Proteomes; UP000255169; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0004586; F:ornithine decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:TreeGrafter.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR CDD; cd00615; Orn_deC_like; 1.
DR FunFam; 3.40.640.10:FF:000008; Lysine decarboxylase, inducible; 1.
DR FunFam; 3.90.1150.10:FF:000032; Ornithine decarboxylase SpeF; 1.
DR Gene3D; 3.40.50.220; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR027568; ODC_inducible.
DR InterPro; IPR005308; OKR_de-COase_N.
DR InterPro; IPR011193; Orn/lys/arg_de-COase.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR027464; Ornithine_deCO2ase_N.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR04301; ODC_inducible; 1.
DR NCBIfam; NF010092; PRK13578.1; 1.
DR PANTHER; PTHR45229:SF3; BIODEGRADATIVE ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR45229; CONSTITUTIVE ORNITHINE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR Pfam; PF03709; OKR_DC_1_N; 1.
DR PIRSF; PIRSF009393; Orn_decarb; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00703; OKR_DC_1; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:CEK26252.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR009393-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000255169}.
FT DOMAIN 350..364
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|PROSITE:PS00703"
FT MOD_RES 355
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR009393-1"
SQ SEQUENCE 720 AA; 81065 MW; F83C44C1F1F7F038 CRC64;
MKKLNIAASA SAISCFETQR EVVDVLHTDF TDISAVVLSV QDINNGVIES IHSLGFNIPI
FAAVCCEEEL NNDVLPSLNG VFELCGDNTD FYGKQLESAA EKYENELLPP FFNTLTKYVE
MGNSTFACPG HQGGQFFRKH PAGRQFFDFY GETIFRSDMC NADVKLGDLL IHEGAPCDAQ
KHAAKVFNAD KTYFVLNGTS ASNKVATNAI LARGDLVLFD RNNHKSNHHG ALIQAGATPV
YLETARNPFG FIGGIDAHCF EEKYLREQIR SVSPERADAP RPFRLAIIQL GTYDGTIYNA
RQVVDKIGHL CDYILFDSAW VGYEQFIPMM KDCSPLLLEL NENDPGIIVT QSVHKQQAGF
SQTSQIHKKD KHIKGQDRYC NHKRFNNAFM LHASTSPFYP LFAALDVNAK MHEGESGRRM
WLECVKNGIE ARKMLLNTCT MIKPFVPDTV DGKPWQEYDT DAMAQDLRFF NFIPGEKWHA
FEGYETSQYF VDPCKLLLTT PGIDTNTGKY THSGIPATIL ANFLRENGIV PEKCDLNSIL
FLLTPAEDLA KMQHLVAQIA RFERFIEEDA LLCDVLPTVY RNNEARYKDY TIGRLCQEMH
DLYVSYDVKQ LQKEMFRKQY FPKVVMNPQD ANIEFVRGNA ELVPLCKAEG RIAAEGALPY
PPGVLCVVPG EVWGGAAQRY FLALEESINL LPGFAPELQG VYLQVDEDGW NRAYGYMMKQ
//
