ID A0A086SVR2_HAPC1 Unreviewed; 654 AA.
AC A0A086SVR2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 18-JUN-2025, entry version 40.
DE SubName: Full=Hsk1-interacting molecule-like protein {ECO:0000313|EMBL:KFH41194.1};
GN ORFNames=ACRE_080960 {ECO:0000313|EMBL:KFH41194.1};
OS Hapsidospora chrysogenum (strain ATCC 11550 / CBS 779.69 / DSM 880 / IAM
OS 14645 / JCM 23072 / IMI 49137) (Acremonium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Bionectriaceae; Hapsidospora.
OX NCBI_TaxID=857340 {ECO:0000313|EMBL:KFH41194.1, ECO:0000313|Proteomes:UP000029964};
RN [1] {ECO:0000313|Proteomes:UP000029964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11550 / CBS 779.69 / DSM 880 / IAM 14645 / JCM 23072 / IMI
RC 49137 {ECO:0000313|Proteomes:UP000029964};
RX PubMed=25291769; DOI=10.1128/genomea.00948-14;
RA Terfehr D., Dahlmann T.A., Specht T., Zadra I., Kuernsteiner H., Kueck U.;
RT "Genome sequence and annotation of Acremonium chrysogenum, producer of the
RT beta-lactam antibiotic cephalosporin C.";
RL Genome Announc. 2:E0094814-E0094814(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFH41194.1}.
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DR EMBL; JPKY01000141; KFH41194.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A086SVR2; -.
DR STRING; 857340.A0A086SVR2; -.
DR HOGENOM; CLU_017715_0_0_1; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000029964; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000029964};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 593..642
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 171..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..285
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..546
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..576
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 654 AA; 73174 MW; FC45B72AB089A2FA CRC64;
MSSRRGPLTN NPNVVNSPLR AAGATSLAAK QKRSHANVQR EEAYGQPPPK KQAVEATVSQ
RAARSPSKLP RSQVLAQRGI SAPSTTRTAP KERVSKPPTV YKTSNQDEGV DKEVWKKHYR
AKFPKMVFYF ESIPDEIRAK LTKRVQYLGA RQEPFFSIEV THVITTRNIP TGRTDTQAAE
PEVQEREPEE QPQTINPSLL DRNTAARRKL LFEFRNVPSR PQHVNDPTKA NKGIRNNDVL
HKAREMGKKI WSLEKFQTMV SVLLESETDS GQQSSRTTNS RATSRPQGQT RGGHENNLLQ
LLQHERINGP TDRDLGVFNR EVSYFKGPYI YVFDMEERHK PMMVREYAKV ANKADGDWPQ
FRSVGNGRCP FVDEEPQERE YRKLREQREQ RREQERARAA AAKPAEVTTV KARDAATAAA
AAATRPVTGK RTLAEMEDGH NKVRAPAASG VLNPAKAALS KQTLQNAFTS RAAEGRVVHG
EPVASGVQPS NVTSAIRSQM ISSQAGVSAI KAGTSKELHG LQRKVLQKTA PTSQEASSRR
PVEHSLEGPS SRSTTLSRQA SKAAQTQEEG GRQAAEGQEK RGQAESQPMK SKKDMKPGYC
ENCQDKFRDF DEHIVSRKHR KFAENTDNWG ELDALLSKLK RSPKDFYMDV DYDL
//
