ID A0A087SNK8_AUXPR Unreviewed; 1005 AA.
AC A0A087SNK8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 10-JUN-2026, entry version 52.
DE SubName: Full=Superkiller viralicidic activity 2-like 2 {ECO:0000313|EMBL:KFM27312.1};
GN ORFNames=F751_4582 {ECO:0000313|EMBL:KFM27312.1};
OS Auxenochlorella protothecoides (Green microalga) (Chlorella
OS protothecoides).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Auxenochlorella.
OX NCBI_TaxID=3075 {ECO:0000313|EMBL:KFM27312.1, ECO:0000313|Proteomes:UP000028924};
RN [1] {ECO:0000313|EMBL:KFM27312.1, ECO:0000313|Proteomes:UP000028924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0710 {ECO:0000313|EMBL:KFM27312.1,
RC ECO:0000313|Proteomes:UP000028924};
RX PubMed=25012212; DOI=10.1186/1471-2164-15-582;
RA Gao C., Wang Y., Shen Y., Yan D., He X., Dai J., Wu Q.;
RT "Oil accumulation mechanisms of the oleaginous microalga Chlorella
RT protothecoides revealed through its genome, transcriptomes, and
RT proteomes.";
RL BMC Genomics 15:582-582(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DExH box helicase family. SKI2 subfamily.
CC {ECO:0000256|ARBA:ARBA00061045}.
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DR EMBL; KL662144; KFM27312.1; -; Genomic_DNA.
DR RefSeq; XP_011400279.1; XM_011401977.1.
DR STRING; 3075.A0A087SNK8; -.
DR GeneID; 23615973; -.
DR KEGG; apro:F751_4582; -.
DR eggNOG; KOG0948; Eukaryota.
DR OrthoDB; 64767at2759; -.
DR Proteomes; UP000028924; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0000460; P:maturation of 5.8S rRNA; IEA:TreeGrafter.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR FunFam; 3.40.50.300:FF:000083; ATP-dependent RNA helicase DOB1; 1.
DR FunFam; 3.40.50.300:FF:000141; ATP-dependent RNA helicase DOB1; 1.
DR FunFam; 1.10.3380.30:FF:000006; DExH-box ATP-dependent RNA helicase DExH10; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 2.40.30.300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR025696; Beta-barrel_MTR4.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C-like.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR050699; RNA-DNA_Helicase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000028924}.
FT DOMAIN 96..252
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 329..532
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 22..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..321
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1005 AA; 110479 MW; EB55B3A609E7B45C CRC64;
MEATAEGLAK AAATREALKK KKRELELIED GPPSKKPTGA APSAVCTHEV ACPKGFDPSS
ITLDPELYGT LEDPQWKGKP AKEYPFVLDS FQAKAVACVE RKENVLVAAH TSAGKTAIAE
YAIAKAFAMG QRVFYTSPIK ALSNQKFREL SEEFGDVGLM TGDVSINPNA ACIVMTTEIL
RSMIYRGSEL LRETAWIVFD EVHYMQDRER GVIWEETIIF APKDARMVFL SATLSNATEF
ADWVASVHQS PCHVVYTEFR PTPLRHFAFP SGGDGLYLVM NEFGEFRDDN FQKLQKVLGK
GGDGGQEGKG KRGGGGGGGK PTGASAAQDL RKIVMLIKER KLDPVIVFSF SRRECESNAM
LMAKADLGAL DFNTQEEKET VDAVFQSALQ CLSEKDRDLR AVAHIYPLLR CGIGIHHSGL
LPIIKEVVEI LFQEQLIKCL FATETFAMGL NMPARTVVFT AMRKWDGQEE RWMGSGEYIQ
MSGRAGRRGK DDRGMTIMMM NNSMDEATCK AIIKGKANPL LSSFRLSYYT LLNLMRRVEG
SGASMEYVIQ HSFSQFQHEK ELPALEARLE EVQAAVAAIG DAGEETAAEY TRLKTRLAEL
ESTLAAEVRK PERCLHYLRP GRLVRVVQEG VDWGWGVVVS AMREERGNAP PAAAPAYHMD
TLLCCAGVVG GEPTPALLDD ERGSMEVIPV PLGLLHALST LRISIPQDLR PPEARRAVLQ
TLKALRGRYP GGALPLLHPV DDMGIEDTGV AAAAAEREEV AAALTANPIS KAERGEGEAS
LMAPLREKAR LMAEAESLAA RMRASQLTSF RDEARHRGAV LRKLGYVDGE GVVTLKGRVA
CEINTADELL ATELMLNGTF NALDRHQLVA MVSCLVQVEK SNEQIRLKES LARPLQALQD
AARRIAEVSV ECRLEVKVDE YVESFWPFLM DVIYAWSKGA SFAEICEMTD LFEGSIVRAT
RRLDELMSEL ERAALAVGDA GLAAKIAESR DTIRRDIMFA ASLYI
//
