ID   A0A091DWC4_FUKDA        Unreviewed;       856 AA.
AC   A0A091DWC4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   28-JAN-2026, entry version 30.
DE   SubName: Full=Zinc finger protein 598 {ECO:0000313|EMBL:KFO34718.1};
GN   ORFNames=H920_03746 {ECO:0000313|EMBL:KFO34718.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO34718.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO34718.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO34718.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN121905; KFO34718.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091DWC4; -.
DR   STRING; 885580.ENSFDAP00000020089; -.
DR   eggNOG; KOG2231; Eukaryota.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0043022; F:ribosome binding; IEA:TreeGrafter.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:TreeGrafter.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:InterPro.
DR   InterPro; IPR057634; PAH_ZNF598/HEL2.
DR   InterPro; IPR056437; Znf-C2H2_ZNF598/HEL2.
DR   InterPro; IPR044288; ZNF598/HEL2.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   InterPro; IPR059042; Znf_C2H2_ZNF598.
DR   PANTHER; PTHR22938:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZNF598; 1.
DR   PANTHER; PTHR22938; ZINC FINGER PROTEIN 598; 1.
DR   Pfam; PF23202; PAH_ZNF598; 1.
DR   Pfam; PF25447; RING_ZNF598; 1.
DR   Pfam; PF23230; zf-C2H2_13; 1.
DR   Pfam; PF23208; zf_C2H2_ZNF598; 1.
DR   SMART; SM00355; ZnF_C2H2; 5.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990}.
FT   DOMAIN          130..151
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS00028"
FT   REGION          267..429
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          460..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        268..284
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        299..311
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        312..341
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..377
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        484..493
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        513..532
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        551..565
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   856 AA;  93952 MW;  8CE9FF6D395C4E19 CRC64;
     MAAMGASLAQ VSSEEVVFGR KLPAFATIPI HQLQHEKKYD IYFADGKVFA LYRQLLQHEC
     PQCPQLPPFG LFGDLEQHMR KQHELFCCKL CLKHLKIFTY ERKWYSRKDL ARHRMQGDPD
     DTSHRGHPLC KFCDERYLDN DELLKHLRRD HYFCHFCDSD GAQDYYSDYA YLREHFREKH
     FLCEEGRCNT EQFTHAFRTE IDLKAHRMAC HSRSRAEARQ NRQIDLQFSF TPRHSRRSEG
     PRTVTGCVLT TGVISGEDYE EVDRYNRQGR AGRASGRGAQ QSRRGSWRYK REEEDREVAA
     AIQASVAAPQ QDETRRSEDH EEGSKPKKEE TAARGSEEPR GPRRLPRTQG EGPGPKEASG
     NDPVGQETSS APGSSTAAVP PSALLPPTPK LKDEDFPSLH ASASSCCPVT APGPVGLTLA
     YPGPARGRNA FQEEDFPALV SSASKPSTTT RSLISAWNSS CGKKGALPTP GAQAASGGSQ
     PPKKPGKGIR GCRKGGSAPM EEEEGGGLIV QELRTTPTTV AVSTLLGSAP THTSTKVSKK
     KKVGSEKPGA MPSPPVPPEH TPNPPVAEQA LDIPVSRAEG PVPVVVNGHT EGPALTRSAP
     KEPPGLPRPL GPLPCPAPQE DFPALGGPCL PRMPPPPGFN AVVLLKGTPP PPPPGLVPPI
     SKPPPGFSNL LPGPHPACIP SPNTTTVKTP RLTPSSRSYL VPENFRERNL QLIQSIKDFL
     QSNEARFSKF KSHSGEFRQG MISAAQYYRS CRDLLGENFQ RIFRELLVLL PDTAKQQELL
     SAHTDFCSRE KPPVAKSKKN KKNAWQASTQ QMGLDCCVCP TCQQVLAHGD VSSHQALHAA
     RDDDFPSLQA IARIIT
//