ID A0A0B7J099_9PROT Unreviewed; 271 AA.
AC A0A0B7J099;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 28-JAN-2026, entry version 36.
DE RecName: Full=hydroxymethylpyrimidine kinase {ECO:0000256|ARBA:ARBA00012135};
DE EC=2.7.1.49 {ECO:0000256|ARBA:ARBA00012135};
GN ORFNames=BN1209_1748 {ECO:0000313|EMBL:CEN56785.1};
OS Candidatus Methylopumilus turicensis.
OC Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC Nitrosomonadales; Methylophilaceae; Candidatus Methylopumilus.
OX NCBI_TaxID=1581680 {ECO:0000313|EMBL:CEN56785.1, ECO:0000313|Proteomes:UP000056322};
RN [1] {ECO:0000313|Proteomes:UP000056322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS-10A-171 {ECO:0000313|Proteomes:UP000056322};
RA Salcher M.M.;
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004948}.
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DR EMBL; LN794158; CEN56785.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B7J099; -.
DR STRING; 1581680.BN1209_1748; -.
DR KEGG; mbac:BN1209_1748; -.
DR HOGENOM; CLU_020520_0_2_4; -.
DR UniPathway; UPA00060; UER00138.
DR Proteomes; UP000056322; Chromosome 1.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0008902; F:hydroxymethylpyrimidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd01169; HMPP_kinase; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CEN56785.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000056322};
KW Transferase {ECO:0000313|EMBL:CEN56785.1}.
FT DOMAIN 12..256
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
SQ SEQUENCE 271 AA; 29548 MW; DC73D7B7AB41AD78 CRC64;
MPPSVMTFAA TDPSSGAGLQ ADILTFASIG CHPLSVVTGI TVQDTVGIEN VMVFDAEWIN
EQARTILEDM QVMAFKIGMI GSVENVAVIA EIMADYPDTP LLIDPVLSSG RGDELANDDV
QAAMIDLLFP QATLITPNSI EARRLAFYND DSDEAENASL DESAQRLLDI GCEYVLVTGT
HERSHEVVNT LYGETGLIKS YNWERLPGSY HGSGCTLTSA IAACIAHGLS MEEAILEAQE
YTWQTLKAGF RPGMGQYIPD RMFWARDDEE E
//
