ID A0A0C2HXZ8_9BACT Unreviewed; 593 AA.
AC A0A0C2HXZ8;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 18-JUN-2025, entry version 41.
DE SubName: Full=NADH dehydrogenase {ECO:0000313|EMBL:KIH77612.1};
GN ORFNames=GFER_02745 {ECO:0000313|EMBL:KIH77612.1};
OS Geoalkalibacter ferrihydriticus DSM 17813.
OC Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfuromonadia;
OC Desulfuromonadales; Geoalkalibacteraceae; Geoalkalibacter.
OX NCBI_TaxID=1121915 {ECO:0000313|EMBL:KIH77612.1, ECO:0000313|Proteomes:UP000035068};
RN [1] {ECO:0000313|EMBL:KIH77612.1, ECO:0000313|Proteomes:UP000035068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17813 {ECO:0000313|EMBL:KIH77612.1,
RC ECO:0000313|Proteomes:UP000035068};
RA Badalamenti J.P., Torres C.I., Krajmalnik-Brown R., Bond D.R.;
RT "Genomes of Geoalkalibacter ferrihydriticus and Geoalkalibacter
RT subterraneus, two haloalkaliphilic metal-reducing members of the
RT Geobacteraceae.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIH77612.1}.
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DR EMBL; JWJD01000001; KIH77612.1; -; Genomic_DNA.
DR RefSeq; WP_040095829.1; NZ_JWJD01000001.1.
DR AlphaFoldDB; A0A0C2HXZ8; -.
DR Proteomes; UP000035068; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR FunFam; 1.20.1440.230:FF:000001; Mitochondrial NADH dehydrogenase flavoprotein 1; 1.
DR FunFam; 3.40.50.11540:FF:000001; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR NCBIfam; NF010120; PRK13596.1; 1.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13237; Fer4_10; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000035068}.
FT DOMAIN 538..567
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 568..593
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 593 AA; 64542 MW; 8D43777BE806C8B6 CRC64;
MAAIEEQIRV LICQGTGGLA AGAKPVEEAF RAEFEKHGVE AKVGKRCTLV GTGCRGLCAN
DVLVDIVIPG QEAVTYDFVK PEMVPQLVEE HILQGQIVEK KKAGNYYQKF LEKQMRVVFS
RCGTIDAESL EEFLAHDGFT GIKKAVTMTP QEVIEEVKKS GLRGRGGGGF PTGVKWSFCA
ASPGKDKYLI CNADEGDPGA FMDRSILEGD PYGLIEGMMI ASYAIGAESG YVYVRAEYPL
AIKRLQKAID VCYEKGFLGK DCLGLGFDFD LRIKAGAGAF VCGEETALMA SIEGERGMPR
PRPPFPAVRG LWTKPTNINN VETFANVSYI FYRGGDWFAS IGTEGTKGTK IFALTGKVKH
TGLVEVPAGI TVREVIYDVC GGILNNRKFK AVQAGGPSGG CLPSEAIDAE VDYDSLIKAG
AMMGSGGLVV MDETTCMVDI ARFFLNFTRA ESCGKCVPCR IGLKIMLDIL ERITEGKGRE
GDIELLEDMC QDIKKASLCG LGQTAPNPVL STIRYFRHEY EAHIHHQRCP SNSCKALLKF
EVVDAACKKC GLCYKICPVD AVRWEKGQLA VIDKEKCTKC TSCYDACRFM AIE
//
