ID A0A0C3S9P8_PHLG1 Unreviewed; 286 AA.
AC A0A0C3S9P8;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 05-FEB-2025, entry version 36.
DE RecName: Full=Transcription initiation factor IIE subunit beta {ECO:0000256|PIRNR:PIRNR016398};
GN ORFNames=PHLGIDRAFT_30492 {ECO:0000313|EMBL:KIP06370.1};
OS Phlebiopsis gigantea (strain 11061_1 CR5-6) (White-rot fungus) (Peniophora
OS gigantea).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Phanerochaetaceae; Phlebiopsis.
OX NCBI_TaxID=745531 {ECO:0000313|EMBL:KIP06370.1, ECO:0000313|Proteomes:UP000053257};
RN [1] {ECO:0000313|EMBL:KIP06370.1, ECO:0000313|Proteomes:UP000053257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=11061_1 CR5-6 {ECO:0000313|EMBL:KIP06370.1,
RC ECO:0000313|Proteomes:UP000053257};
RX PubMed=25474575; DOI=10.1371/journal.pgen.1004759;
RA Hori C., Ishida T., Igarashi K., Samejima M., Suzuki H., Master E.,
RA Ferreira P., Ruiz-Duenas F.J., Held B., Canessa P., Larrondo L.F.,
RA Schmoll M., Druzhinina I.S., Kubicek C.P., Gaskell J.A., Kersten P.,
RA St John F., Glasner J., Sabat G., Splinter BonDurant S., Syed K., Yadav J.,
RA Mgbeahuruike A.C., Kovalchuk A., Asiegbu F.O., Lackner G., Hoffmeister D.,
RA Rencoret J., Gutierrez A., Sun H., Lindquist E., Barry K., Riley R.,
RA Grigoriev I.V., Henrissat B., Kues U., Berka R.M., Martinez A.T.,
RA Covert S.F., Blanchette R.A., Cullen D.;
RT "Analysis of the Phlebiopsis gigantea genome, transcriptome and secretome
RT provides insight into its pioneer colonization strategies of wood.";
RL PLoS Genet. 10:E1004759-E1004759(2014).
CC -!- FUNCTION: Recruits TFIIH to the initiation complex and stimulates the
CC RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase
CC activities of TFIIH. Both TFIIH and TFIIE are required for promoter
CC clearance by RNA polymerase. {ECO:0000256|ARBA:ARBA00025581,
CC ECO:0000256|PIRNR:PIRNR016398}.
CC -!- SUBUNIT: Tetramer of two alpha and two beta chains.
CC {ECO:0000256|PIRNR:PIRNR016398}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR016398}.
CC -!- SIMILARITY: Belongs to the TFIIE beta subunit family.
CC {ECO:0000256|PIRNR:PIRNR016398}.
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DR EMBL; KN840519; KIP06370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C3S9P8; -.
DR STRING; 745531.A0A0C3S9P8; -.
DR HOGENOM; CLU_056580_1_0_1; -.
DR OrthoDB; 3907302at2759; -.
DR Proteomes; UP000053257; Unassembled WGS sequence.
DR GO; GO:0005673; C:transcription factor TFIIE complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0001097; F:TFIIH-class transcription factor complex binding; IEA:TreeGrafter.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:UniProtKB-UniRule.
DR CDD; cd07977; TFIIE_beta_winged_helix; 1.
DR InterPro; IPR040501; TFA2_Winged_2.
DR InterPro; IPR016656; TFIIE-bsu.
DR InterPro; IPR003166; TFIIE_bsu_DNA-bd.
DR PANTHER; PTHR12716:SF8; TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA; 1.
DR PANTHER; PTHR12716; TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT; 1.
DR Pfam; PF18121; TFA2_Winged_2; 1.
DR Pfam; PF02186; TFIIE_beta; 1.
DR PIRSF; PIRSF016398; TFIIE-beta; 1.
DR PROSITE; PS51351; TFIIE_BETA_C; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR016398};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR016398};
KW Reference proteome {ECO:0000313|Proteomes:UP000053257};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR016398};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR016398}.
FT DOMAIN 55..132
FT /note="TFIIE beta"
FT /evidence="ECO:0000259|PROSITE:PS51351"
FT REGION 19..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 286 AA; 32154 MW; 86B1F8C7BEAD8FE4 CRC64;
MSISSLARDA AAFKSALSRQ DYSSWHAQPP PLQASQEPPA EPSKKKKRPK SNVVYSQPTE
TGKGTDVNTQ LVYAVNYLKT TGNPMRLQDL AAYAQVPLDT DKVLLEKFKS HDRVVHDPKT
DLYSYRFDFN VRNKISLLTE IQRQTRKGGG LSVRTLKESW KEAPQAIEEL EKEGEVYVTR
TLKDGQLRMV FWNEIKPDEE AGGTQVEKEF LDLWHSLQVP NDVDLLKQLA NEGLQATAGE
TLVPKGLAGK KKGKKTAPRQ RQIRLTNTHL KGQIDLSRDY VAPGKS
//
