ID   A0A0D2CZ50_9EURO        Unreviewed;       832 AA.
AC   A0A0D2CZ50;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   05-FEB-2025, entry version 26.
DE   RecName: Full=Choline kinase N-terminal domain-containing protein {ECO:0000259|Pfam:PF04428};
GN   ORFNames=PV04_02738 {ECO:0000313|EMBL:KIW70471.1};
OS   Phialophora macrospora.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX   NCBI_TaxID=1851006 {ECO:0000313|EMBL:KIW70471.1, ECO:0000313|Proteomes:UP000054266};
RN   [1] {ECO:0000313|EMBL:KIW70471.1, ECO:0000313|Proteomes:UP000054266}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 27337 {ECO:0000313|EMBL:KIW70471.1,
RC   ECO:0000313|Proteomes:UP000054266};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capronia semiimmersa CBS27337.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC       {ECO:0000256|ARBA:ARBA00038211}.
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DR   EMBL; KN846957; KIW70471.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D2CZ50; -.
DR   HOGENOM; CLU_012712_4_0_1; -.
DR   Proteomes; UP000054266; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR   GO; GO:0004103; F:choline kinase activity; IEA:TreeGrafter.
DR   GO; GO:0004305; F:ethanolamine kinase activity; IEA:TreeGrafter.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:TreeGrafter.
DR   CDD; cd05157; ETNK_euk; 1.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   InterPro; IPR007521; Choline_kin_N.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR   PANTHER; PTHR22603:SF93; RE24176P; 1.
DR   Pfam; PF04428; Choline_kin_N; 1.
DR   Pfam; PF01633; Choline_kinase; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054266}.
FT   DOMAIN          145..215
FT                   /note="Choline kinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04428"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          52..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          677..722
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          744..789
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        54..69
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        697..717
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        765..785
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   832 AA;  93496 MW;  8CDFA83F716B0EBC CRC64;
     MSYFSLDDNN PTEPSPLAGG GSMTSGATPT ESKTADLRGV LSQVADWLQE EKSKRHKWSR
     HRHSHHHGQH LQTPEIQPSE VRTYDSASDQ GQDVSLEKLE SILQGFTSDA TRSMRKASTA
     GLRKGSIASK FKQARSAPAA SSDTEFFGDD VLVPNVEAKL DNTKTMAFTG GLTEGNETDK
     AKRKDYDHWV TFKQDILRLT HTLKIKGWRR IPLERAAEID VARLSGALTN AVYVVHPPKN
     LPELDKSAQS DSTSAPASLV PRQRASSLLL RIYGPQVEHL IDRDAELNIL RRLARKRIGP
     RLLGSFDNGR FEEFLQAKTL TAEDLRVPET SKQIAKRMRE LHDGIELLES ELDSGPATFV
     NWDKWVDRCE KVITWLDAQI HQAEEELKAG TSRRNSLVNL RYVRRGLICG VDWPVFRRTY
     DAYRKRLIAE SGGPEGIRKQ LVFAHNDTQY GNLMRLQPSG TSPLLQPSNH HKQLVVIDFE
     YAAQNLAGLE FANHFTEWCY NYHNTPDKSF VCDTRRYPTE QEQYRFVRSY VMHRPQFNPS
     ASATPKMEAR EKTNISDFML DARTPGGASG SSTGYIGGAG AVFDYDKEET EREKAQEEEI
     QRLLRQARVW RLANSAMWVA WGIVQAKVPE LDAMEEKEKL GTKAGHLLKE RRKSLTDKVS
     AGEMKIVDKV KKMVADHGYK GGQRPLPMSD PLTEEERELR MESHWDRPEG RAQETAHQEG
     NGDVVIEQSD HASVDGTSAE AMPDLEHGVT SNNGHDTSDG APESHSGTQP GADSSSHSGT
     NSPEQESSEE FDYLAYAQDR AMFFWGDCIQ MGLIKEEELP KELVEKVKVV PY
//