ID   A0A0D2D114_9EURO        Unreviewed;       274 AA.
AC   A0A0D2D114;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   05-FEB-2025, entry version 30.
DE   RecName: Full=Protein lifeguard 4 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PV04_03371 {ECO:0000313|EMBL:KIW71176.1};
OS   Phialophora macrospora.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX   NCBI_TaxID=1851006 {ECO:0000313|EMBL:KIW71176.1, ECO:0000313|Proteomes:UP000054266};
RN   [1] {ECO:0000313|EMBL:KIW71176.1, ECO:0000313|Proteomes:UP000054266}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 27337 {ECO:0000313|EMBL:KIW71176.1,
RC   ECO:0000313|Proteomes:UP000054266};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capronia semiimmersa CBS27337.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000256|RuleBase:RU004379}.
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DR   EMBL; KN846957; KIW71176.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D2D114; -.
DR   STRING; 5601.A0A0D2D114; -.
DR   HOGENOM; CLU_058671_0_0_1; -.
DR   Proteomes; UP000054266; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd10429; GAAP_like; 1.
DR   InterPro; IPR006214; Bax_inhibitor_1-related.
DR   PANTHER; PTHR23291; BAX INHIBITOR-RELATED; 1.
DR   PANTHER; PTHR23291:SF50; PROTEIN LIFEGUARD 4; 1.
DR   Pfam; PF01027; Bax1-I; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004379};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054266};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU004379};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU004379}.
FT   TRANSMEM        73..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        106..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        133..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        160..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        216..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        247..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   274 AA;  30976 MW;  C80D16269C457AC6 CRC64;
     MASSTKYQPA PQRDSLDEQH YPQAPPEYQA AGPSDVGYGT PRAEDDNVPD DFKFGGSVSE
     ATLDIRMQFI RKVYTILTVQ ILLTAGLSSL SFFSLGYRTW IQSNSWMMWV SLFGAIGFML
     LTFWKRKSYP TNMIFLAGFT ALEAYSISVI TSFYESRIVI EALIITLGIF VFLTLFACQT
     KYDFTSWMPY LFGALWILII FGFMAAFFPH SSTMETVYGA VAALVFSGYI LVDTQLVLRH
     YHVEEEIAAS ISLYLDVLNL FLAILRILNS QNNN
//