ID   A0A0D2XCY9_FUSOF        Unreviewed;       302 AA.
AC   A0A0D2XCY9;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   18-JUN-2025, entry version 43.
DE   RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE            EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
OS   Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=660025 {ECO:0000313|EnsemblFungi:FOXG_01764P0, ECO:0000313|Proteomes:UP000002489};
RN   [1] {ECO:0000313|Proteomes:UP000002489}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fo5176 {ECO:0000313|Proteomes:UP000002489};
RX   PubMed=21942452; DOI=10.1094/mpmi-08-11-0212;
RA   Thatcher L.F., Gardiner D.M., Kazan K., Manners J.;
RT   "A highly conserved effector in Fusarium oxysporum is required for full
RT   virulence on Arabidopsis.";
RL   Mol. Plant Microbe Interact. 25:180-190(2012).
RN   [2] {ECO:0000313|EnsemblFungi:FOXG_01764P0}
RP   IDENTIFICATION.
RC   STRAIN=4287 / CBS 123668 / FGSC 9935 / NRRL 34936
RC   {ECO:0000313|EnsemblFungi:FOXG_01764P0};
RG   EnsemblFungi;
RL   Submitted (MAR-2025) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC         EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A0D2XCY9; -.
DR   STRING; 426428.A0A0D2XCY9; -.
DR   EnsemblFungi; FOXG_01764T0; FOXG_01764P0; FOXG_01764.
DR   Proteomes; UP000002489; Unassembled WGS sequence.
DR   GO; GO:0035861; C:site of double-strand break; IEA:EnsemblFungi.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR   CDD; cd20356; Rcat_RBR_HHARI-like; 1.
DR   FunFam; 1.20.120.1750:FF:000007; RBR-type E3 ubiquitin transferase; 1.
DR   Gene3D; 1.20.120.1750; -; 1.
DR   InterPro; IPR045840; Ariadne.
DR   InterPro; IPR031127; E3_UB_ligase_RBR.
DR   InterPro; IPR002867; IBR_dom.
DR   InterPro; IPR044066; TRIAD_supradom.
DR   PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR   Pfam; PF19422; Ariadne; 1.
DR   Pfam; PF01485; IBR; 1.
DR   Pfam; PF22191; IBR_1; 1.
DR   SMART; SM00647; IBR; 2.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS51873; TRIAD; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002489};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          1..132
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51873"
SQ   SEQUENCE   302 AA;  34514 MW;  BAE010B9AD678338 CRC64;
     MSKTRTILSG ALPPDCPNAL ECGVKKKDLG KIVPTVECRC GYRFCFGCPN PDHQPAPCEL
     VKKWLKKCAD DSETANWISA NTKECPKCNS TIEKNGGCNH MTCRKCKYEF CWMCMGLWSE
     HGTSWYNCNR YEEKSGSEAR DAQAKSRTSL ERYLHYYNRY ANHEQSAKLD KDIAQKTEKK
     MVQLQTASGM SWIEVQYLNS ASQALQTCRQ TLKWTYAFAF YLARNNLTEI FEDNQKDLEM
     AVENLSEMFE KPTAELSDPK LKVDIMDKTS YCNKRRVILL EDTAENLAIG ITTLTPSSIP
     FI
//