ID A0A0D8XSG6_DICVI Unreviewed; 782 AA.
AC A0A0D8XSG6;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 18-JUN-2025, entry version 44.
DE SubName: Full=Collagenase NC10 and Endostatin {ECO:0000313|EMBL:KJH46684.1};
GN ORFNames=DICVIV_07248 {ECO:0000313|EMBL:KJH46684.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH46684.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH46684.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH46684.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
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DR EMBL; KN716340; KJH46684.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8XSG6; -.
DR STRING; 29172.A0A0D8XSG6; -.
DR OrthoDB; 5983381at2759; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 1.20.5.320; 6-Phosphogluconate Dehydrogenase, domain 3; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023:SF1112; COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR Pfam; PF01391; Collagen; 1.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..782
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002335914"
FT DOMAIN 471..504
FT /note="Collagen type XV/XVIII trimerization"
FT /evidence="ECO:0000259|Pfam:PF20010"
FT DOMAIN 599..763
FT /note="Collagenase NC10/endostatin"
FT /evidence="ECO:0000259|Pfam:PF06482"
FT REGION 36..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..346
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 782 AA; 86481 MW; 122266029FA04526 CRC64;
MMFIIYLLIF VLPYLYIADP PNHQLVNNEK KFSNLDDNFG PTPSPNETPN LESTTELSSP
VTNSMIKVDD ELGGVMFHFT IAQDDEAASD KMSNLNKNNE FTLPPMFEPI EGAIQELKII
DDPSEAAKQC DELWGAIQEL KIIDDPSEAA KQCDELWTDD EGSGLDQFKD QGDKEVKNDL
EYPSSSISFP VSPEESDQKQ LNDRDERDLL YPFGDSLLLP FHRHKSPNSI ERVKECYRGL
LESIEAILHK SESYDFLIPE NVQSTIKGEK GDPGQPGVCL QQCRDGMPGP SGPIGPQGPQ
GVAGPPGPPG QPGEPGYVQQ SVSGGAEVRA MPGPPGVAGP PGPPGPRGMQ GPRGETGYPG
RDGRDFRGLS EHDIELIVRH PLLKGEKGEC IHSAASELRP VLRDISHDNL RSDYYKGEKG
DRGMPGPPGA TGPIGPPGPP GSFGHPGSVY QIHEGGRSIA RVYPSTHELF SSRVHTGTLA
FATSTQQLYI KVNNGWKEVM LGTYHPIVEQ RQSMPIVSEP DLNSNHLEYW GTARSQSQPE
IRSLASSPRE AQQPSSDKKE DLPSVSIPAY MQDTPKTARL HPNKLPSDYF PSFEKDKVIH
MIALNNPYDG NMHGMRGADL QCYREARMTG FTTTFRAMLS SNVQDMLRIV HSVDWDTPVV
NLRGEHLFPS WRAVLNDGQR TARPIYSFDK RDILTNDHWP HKRIWHGTKA GGIRAGEYCD
GWRNNDSSLS AMSGDLRIPG GLISDAKLMS CDQKLVVLCV ENMSKYHGDR ILKKKRVGEI
VW
//
