ID A0A0D9P4U1_METAN Unreviewed; 1153 AA.
AC A0A0D9P4U1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 08-OCT-2025, entry version 37.
DE RecName: Full=Histone deacetylase domain-containing protein {ECO:0000259|Pfam:PF00850};
GN ORFNames=H634G_03758 {ECO:0000313|EMBL:KJK81224.1};
OS Metarhizium anisopliae BRIP 53293.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1291518 {ECO:0000313|EMBL:KJK81224.1, ECO:0000313|Proteomes:UP000054544};
RN [1] {ECO:0000313|Proteomes:UP000054544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRIP 53293 {ECO:0000313|Proteomes:UP000054544};
RX PubMed=25102932; DOI=10.1186/1471-2164-15-660;
RA Pattemore J.A., Hane J.K., Williams A.H., Wilson B.A., Stodart B.J.,
RA Ash G.J.;
RT "The genome sequence of the biocontrol fungus Metarhizium anisopliae and
RT comparative genomics of Metarhizium species.";
RL BMC Genomics 15:660-660(2014).
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DR EMBL; KE384727; KJK81224.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D9P4U1; -.
DR STRING; 1291518.A0A0D9P4U1; -.
DR OrthoDB; 5232919at2759; -.
DR Proteomes; UP000054544; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:TreeGrafter.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:TreeGrafter.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProtKB-ARBA.
DR CDD; cd09998; HDAC_Hos3; 1.
DR FunFam; 3.40.800.20:FF:000011; Histone deacetylase HOS3; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR053244; HDAC_HD_type_1.
DR InterPro; IPR000286; HDACs.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR47558; HISTONE DEACETYLASE HOS3; 1.
DR PANTHER; PTHR47558:SF1; HISTONE DEACETYLASE HOS3; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054544}.
FT DOMAIN 258..585
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 654..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 728..1061
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1128..1153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..40
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..88
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..132
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..697
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 845..854
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..876
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 956..976
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1036..1054
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1131..1153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1153 AA; 124067 MW; 0992C4352D0FC1FA CRC64;
MSHSIHGSLS PRQGPTSPAS NRANDDNSGL TQSLSQLSLT NEPKTLKPLP SPRNSWGTPA
KPPPRRSSSA SPLPRTPSRS PSNGPGSRRA SHAESPPLLR KASMNSLHSA NGVAPGRPLA
RRSSSSHIIS TSPANRTPPE EKPPLTARSI ASDYFAAELA EYHGATPTLP TDTVVILNDA
VYGHRFSRPR TSRSALSTIV ERPERIKAAV LGISTAYVRL GGRHCQGHLP IHPKRNLSDI
NSIPFRIHKT TRQLSLLSSA VTNVHGTKWM EELKLMCGSA ESILAMGGKE LQRPDISRGP
EHPAPQKLHE GDLYLCEESL NAMQGALGAV CEAVDTVFGS GPRKAFVGVR PPGHHCSASH
PSGFCWVNNV HVGIMHAALQ HGLTHAAIID FDLHHGDGSQ AITWQHNARA NAANKSHASW
KRMSIGYFSL HDINSYPCEM GDEDKVKNAS LCIDSAHGQS IWNIHLQSWK TEQEFWTLYE
STYAILLEKT RRYLKNETAK LRASNQVPKA AVFFSAGFDA SEWESAGMQR HHVNVPTEFY
ARLSQDVVKL AAEEGLAVDG RVISVLEGGY SDRALCSGIM SHLSGLVGGS HDKEQSTIET
EQESSGLAYE MGQRIGAINL NADPIMKPPA SMYDPAWWAT NELDLLEEPE APLAVPRKPR
NSTPPTYSSP TQASTARVAD PMKMKNSLSG LSASYSKVPQ RPTSPPPPEV PWHIAAKELC
KTLIPSDRQT DSCTAEDLNA EASRARRDRQ SLLLGNQPPT PSGSDRSLSR MSLRERKSRP
IGPIDEEMSE VLPKTRRKPA STPISSPAKA GRSTPRPAGA QSARKSSRRL SVASTNLPPP
REEPPPVPPI PATAPVPSRT ASRPNSRTGR TQSSNKVPVK KTQAVPSRID PAPKGGRNAA
RASTPAKGAK QSTIAADTPT PATGLPLNAA GNDAKSDIDS LTDGVKKIRI NLITKAQRDG
KQKAKPEQSV EPHRQLGQDS SIVKSEKPPT PEGMSSIPNA PEQLPTQLAP ASGLPEAPPT
PSLSGGISTP VEEMYTSNTS SPTPTPSIPT GSSPDVPHVT IQPASDANDV FIPYQPEGPE
PVTMVQHEHL KWLPPNIQTP SSVTPVHTPL PSATKTKDSL FHYTSGIRFA PRPDTELQGR
PGSVDKPRTG HEQ
//
