ID   A0A0E0B4R0_9ORYZ        Unreviewed;      1413 AA.
AC   A0A0E0B4R0;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   28-JAN-2026, entry version 33.
DE   RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Oryza glumipatula.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=40148 {ECO:0000313|EnsemblPlants:OGLUM09G15560.2};
RN   [1] {ECO:0000313|EnsemblPlants:OGLUM09G15560.2}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (APR-2015) to UniProtKB.
RN   [2] {ECO:0000313|EnsemblPlants:OGLUM09G15560.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Zhang J., Kudrna D., Lee S., Talag J., Welchert J., Wing R.A.;
RT   "OgluRS3 (Oryza glumaepatula Reference Sequence Version 3).";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EnsemblPlants; OGLUM09G15560.2; OGLUM09G15560.2; OGLUM09G15560.
DR   Gramene; OGLUM09G15560.2; OGLUM09G15560.2; OGLUM09G15560.
DR   HOGENOM; CLU_002480_1_0_1; -.
DR   Proteomes; UP000026961; Chromosome 9.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   CDD; cd08958; FR_SDR_e; 4.
DR   FunFam; 3.40.50.720:FF:000085; Dihydroflavonol reductase; 2.
DR   FunFam; 3.40.50.720:FF:000382; NAD(P)-binding Rossmann-fold superfamily protein; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 6.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR050425; NAD(P)_dehydrat-like.
DR   PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR   PANTHER; PTHR10366:SF500; OS09G0491852 PROTEIN; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   Pfam; PF01370; Epimerase; 4.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 5.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000026961}.
FT   DOMAIN          13..141
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
FT   DOMAIN          322..499
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
FT   DOMAIN          650..770
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
FT   DOMAIN          799..1031
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
FT   DOMAIN          1088..1322
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   1413 AA;  155281 MW;  AFAB4AB226F54B2A CRC64;
     MASPAPAPAP PRVCVTGGGG FIASWLVKLL LSRGYAVHAT LRDPCDPKNA HLERLQDASQ
     AAPANLRLFT ADVLDLDTLT HAVQGCDGVF HLATPVPEDK IVDPEAKVID PAVKGTLNVL
     KACSVAKVQK VVVMSSNAAV DVNPDWPPNR LKYESCWSDL ALCEKNEPTV NISSKFLIYV
     MKGGPDAMNN KLWHIVDVRD VADALLLLYE KPESSGRYVC SSDHICTRDL VNLLKKMYPN
     IPDVEHKASL TSQKLMSLGW APRRLEETLS DSVDCYENAG ILKILDGHPC RLPHLFSDLD
     FDMAGQQEQP EMAPPPPRRR VVCVTGAGGF VGSWLVELLL SRGYAVHATV RDPDDPKNAF
     LKQLENAPEN LQLFEADVLD CGSLTAAFAG CEGVFHLATP VPEEKIKEMM APTVEGTRNV
     LEACSAASVQ KLVVASSIAT VCLNPSWPQD MPKDETSWSD KKLCIENEDW YSVAKIEAEE
     MALEYGKKNG LHTVEINTSS KVLLYMIKGG DGPHVMNNKF WPMVDVRDVA DALLLAYHKA
     GPSERYLCTL EQMDLKHLLD LMKNMYPNYN YADKMVDVDY KVEVTSEKLK NLGWNPRKRE
     ETLADNIEFF EKAGLLDGRP CRLPYFAGLR FQSDQSGKVQ PEMPPRRVCV TGAGGFIGSW
     LVKLLLSRGY FVHGTVRNPD DPKNAFLKQL ENATENLQLF KADVLDGGSL TAAFAGCEGV
     FHPATPVPEE QMKEMMAPAV KGTRNVLEAC SAAGVQKLVV VSSIAAVFFN PSWPHDRPKD
     ETSWRNMAAM ASPPPTTRVC VTGAGGFIGS WLVKLLLSRG YAVHATLRDP CDPKNAHLKQ
     LDGASEMLSL FKADVLDAGE LSAAIAGCEG VFHVASPVPG DKIVDPELEV MAPAVKGTLN
     VLEVCSSSKK VQKVVVVSST AAVHYNPNWP PGKPKDESCW SDRKICMEKK EWYSASKVIA
     EKMALEYAEK KGLNVVTVCP CLVFGPQLQP TVNTSNELLI YITKGGPNVM RNMLLHIVDV
     RDVAEALILS LGWKPRKLEE TLTDSIEYYE KTGILQDAGG RPCPTLHTEV QWWQPEMTPP
     PPPPRRLVCV TGAGGFIGSW LVKLLLSRGY AVHATVRDPH DPKNAFLKQL ENAPENLRLF
     KADVLDGGSL TAAFAGCEGV FHPATPVPEE KTKEMLDPAV KGTRNVLEAC SAAGVQKLVV
     VSSIGAVCFN PSLPRDRIID ETCWSDKKSC KENENWYCLA KTEAEEMALE YSEKNGLHVI
     TVCPALVLGP LLQTVLLSTS SKVLLYVMKG GPDAIGNTFF PIVDVRDVAD ALLLVYDKAG
     PSERYICSQE QMDTKDFLDL MKSMYPNYSY TFKVVDVDTR VGLTSEKLKK LGWKPRKLEE
     TLVDSVESHE KAGLVDDEPC RLPYLYRVPD AQE
//