ID A0A0E0KJ01_ORYPU Unreviewed; 623 AA.
AC A0A0E0KJ01;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 08-OCT-2025, entry version 30.
DE RecName: Full=YTH domain-containing family protein {ECO:0000256|RuleBase:RU369095};
OS Oryza punctata (Red rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4537 {ECO:0000313|EnsemblPlants:OPUNC03G31210.1};
RN [1] {ECO:0000313|EnsemblPlants:OPUNC03G31210.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
RN [2] {ECO:0000313|EnsemblPlants:OPUNC03G31210.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang J., Kudrna D., Lee S., Talag J., Welchert J., Wing R.A.;
RT "OpunRS2 (Oryza punctata Reference Sequence Version 2).";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Specifically recognizes and binds N6-methyladenosine (m6A)-
CC containing RNAs, and regulates mRNA stability. M6A is a modification
CC present at internal sites of mRNAs and some non-coding RNAs and plays a
CC role in mRNA stability and processing. {ECO:0000256|RuleBase:RU369095}.
CC -!- SIMILARITY: Belongs to the YTHDF family.
CC {ECO:0000256|RuleBase:RU369095}.
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DR AlphaFoldDB; A0A0E0KJ01; -.
DR SMR; A0A0E0KJ01; -.
DR STRING; 4537.A0A0E0KJ01; -.
DR EnsemblPlants; OPUNC03G31210.1; OPUNC03G31210.1; OPUNC03G31210.
DR Gramene; OPUNC03G31210.1; OPUNC03G31210.1; OPUNC03G31210.
DR eggNOG; KOG1901; Eukaryota.
DR HOGENOM; CLU_017795_5_1_1; -.
DR OMA; YDAPKYS; -.
DR Proteomes; UP000026962; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0003729; F:mRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:1990247; F:N6-methyladenosine-containing RNA reader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0061157; P:mRNA destabilization; IEA:TreeGrafter.
DR CDD; cd21134; YTH; 1.
DR Gene3D; 3.10.590.10; ph1033 like domains; 1.
DR InterPro; IPR007275; YTH_domain.
DR InterPro; IPR045168; YTH_prot.
DR PANTHER; PTHR12357:SF99; YTH DOMAIN-CONTAINING PROTEIN ECT2-RELATED; 1.
DR PANTHER; PTHR12357; YTH YT521-B HOMOLOGY DOMAIN-CONTAINING; 1.
DR Pfam; PF04146; YTH; 1.
DR PROSITE; PS50882; YTH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000026962};
KW RNA-binding {ECO:0000256|RuleBase:RU369095}.
FT DOMAIN 434..571
FT /note="YTH"
FT /evidence="ECO:0000259|PROSITE:PS50882"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 566..599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 67133 MW; 69E16243A9446214 CRC64;
MAAVAPGAGD QATDMMQKLS LESKKEGAAP DAAKKPAGMT YGSASAGDAQ NAASPVDRSI
TPLLQEAVNA NILYQTNGYG PSAYYYPTGY DGSANEWDSR YAGHDGTEMP PQSVYGDMYH
GYGYAPYGPY PSGSPVPTVG HDGQSYGAQH YQYPGQYYQQ PAPTNASHGV NAVNSQSEMP
SVAAHQARVP VDSAKASANG TANGMANTNS SSLPHKQTHQ NVSVANSSSY GRGTLQGGPS
ANNYGHSGLH SPVQWYDGPV YSNGHQRSNT NSTPYGSNSY LAKNQSQRPT ANLMGMHAQI
PSSGMGLTSP SYHTRMYPDS RLYGQYGNTL KTGLGFGSNM YNSRNNGRWG IVDSKYKPRG
RASFGFGSEN QDGFTELNRG PRSGGFKHQK QFGPSVTIAV KGQAIPSVGK QENSAILDRG
QFNQEGFPVT YKDAKFFVIK SYSEDDVHKS IKYNVWASTP NGNKKLDAGY REAQEKSSEC
PVFLFFSVNT SGQFVGVAEM VGPVDFDKTV DYWQQDKWNG CFPIKWHIVK DVPNNILKHI
TLDNNDNKPV TNSRDTQEVK LEQGLEMGSL DNASHEKEKN AIDGKSTAQK QALSKEGTPI
VGEMLNASKS IGHAVESNVT NGN
//
