ID A0A0F8B1I8_CERFI Unreviewed; 1395 AA.
AC A0A0F8B1I8;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 18-JUN-2025, entry version 35.
DE SubName: Full=Checkpoint serine/threonine-protein kinase bub1 {ECO:0000313|EMBL:KKF95056.1};
DE EC=2.7.11.1 {ECO:0000313|EMBL:KKF95056.1};
GN Name=bub1 {ECO:0000313|EMBL:KKF95056.1};
GN ORFNames=CFO_g2581 {ECO:0000313|EMBL:KKF95056.1};
OS Ceratocystis fimbriata f. sp. platani.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=88771 {ECO:0000313|EMBL:KKF95056.1, ECO:0000313|Proteomes:UP000034841};
RN [1] {ECO:0000313|EMBL:KKF95056.1, ECO:0000313|Proteomes:UP000034841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFO {ECO:0000313|EMBL:KKF95056.1,
RC ECO:0000313|Proteomes:UP000034841};
RA Belbahri L.;
RT "Genome sequence of Ceratocystis platani, a major pathogen of plane
RT trees.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF95056.1}.
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DR EMBL; LBBL01000123; KKF95056.1; -; Genomic_DNA.
DR OrthoDB; 643121at147550; -.
DR Proteomes; UP000034841; Unassembled WGS sequence.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:TreeGrafter.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProtKB-ARBA.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0051754; P:meiotic sister chromatid cohesion, centromeric; IEA:TreeGrafter.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR CDD; cd13981; STKc_Bub1_BubR1; 1.
DR FunFam; 1.25.40.430:FF:000003; Checkpoint serine/threonine-protein kinase BUB1; 1.
DR Gene3D; 1.25.40.430; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR015661; Bub1/Mad3.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR013212; Mad3/Bub1_I.
DR InterPro; IPR012572; Mad3/Bub1_II.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR14030:SF4; BUB1 KINASE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR14030; MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1; 1.
DR Pfam; PF08311; Mad3_BUB1_I; 1.
DR Pfam; PF08171; Mad3_BUB1_II; 1.
DR SMART; SM00777; Mad3_BUB1_I; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51489; BUB1_N; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Kinase {ECO:0000313|EMBL:KKF95056.1};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Reference proteome {ECO:0000313|Proteomes:UP000034841};
KW Transferase {ECO:0000313|EMBL:KKF95056.1}.
FT DOMAIN 63..222
FT /note="BUB1 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51489"
FT DOMAIN 1014..1395
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 17..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..461
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..484
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..677
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..763
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..812
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..827
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 855..870
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..888
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1395 AA; 156838 MW; F0BD9F57351EFC61 CRC64;
MSDAQDPVDF EILEGQKENI QSLPGGRSAR KLAQLYSPNP LKPLSTPNPA DTQDAHSAKR
AEFEQEVAAI DESDDPLDVY DRYVRWTLEA YPSAQATPQS QLDQLLERAT KSFVSSAQYR
NDPRYLKMWV YYIQFFSDAP RETFLFLSRH GIGESLALFY EEYATWLEGQ SRWAQAEEVY
KLGIECEARP QARLLRKFKE FEHRMSEQPA ESVRPTSPAI PPVRAALAAK VDPFAIAMLP
DDPQVPRPSA GLPGYASPKA NKTKGKMAIF SDSNAKEPAM GERATAGSRG WDSIGSLSER
KKENVIEPKP WAGETLKAGG KKPSGPKMAI FKDTSQKSKI HSSQPSQTVF DQLSQYKISS
ASDQVVVNPR TGKMERILVD LEVIYPQPDV RGAELSFEEV WARNRGWLDR SWEEEEGEER
EMTMVDVDES VSQYDESFIL QQQRLQHEEE QRRQQEQEQQ KKPVQRQKKL EMYHDDTSIS
RDENSPIQGT SRLEHQNMAV CRDSPEGRPH KMQIHRDGVV PQKQKLSIHR DDEPVVPKKQ
KMAIHRDEFV DEENRLVSSL SSPVARPPVQ KIPIHRDEPV DENGMVIQQQ QKPAKSKKKI
MDYNETQIIK AKLDSPSRPK ISKRKSIAAD PTMTIHTKSA TDDIYDIFNA PLPSKTGDKG
GSDDDEEYDS DEYESDGESM GTTRNVDLED SDDDDAKSDW SDYTVKKKAS GLDDLTCKTN
PDFTVRGVID DEEEEEEEDD GDDDDDESDE EEEGETEAEE QSEISEMRGP DEGNQSSQFS
EQEPSLQSVE NDLVAQTGQQ TQQQQSHTIT HTKFIPVPPE DYVPPTRPYR DPAEVANNRL
PFMTPITERT EMSLDFQQTQ GKTPSRSRGT MHSMPEEDED EDEDEDEEKA YNPTTDLNEA
MSSPLIDMGK SPISYNTKIA QPAFPKPTTK ALAPKGPIIK DLQINPMDEG IRSQILDKTR
PPLATYVGFF DHRDQNYEKG NEIRRFARAM SKAKSSGDHL AGPVIRLPDS QGMYTVKKEL
GAGAFAPVYL VENSAPYSSQ ADEAIVLLGP KAPLSRHRNH LEALKMETPP SLWEFFMMRL
THNRLGPQDR AAASLSYAHE LHLYRDEGFL VLPYHPHGTL LDVVNHFRAE PSGVMDEQLA
MFFSIELLRT VEALHSKAIM HGDLKADNCL LRIDAASSAS GPASALATFG SAGSPDPETT
VLTSQYHIDG SGGWATRGVT LIDFGRGIDM RAFVADQVQF IADWKTTSQD CAEMREGRSW
TWHIDYHGLA GIIHTLLFGK YIETVRMDQG PGTTGGISGT AVGGPLNIGI GSRKYRIRES
LKRYWQTDIW AECFDLLLNP GHFVERDGEG GRMPVTRGLK RVRESMEEWL SANCERGAGL
KTLVNKVEAF AKGRR
//
