ID A0A0J1IR04_9FIRM Unreviewed; 631 AA.
AC A0A0J1IR04;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 28-JAN-2026, entry version 45.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:KLU67121.1};
GN ORFNames=DEAC_c10600 {ECO:0000313|EMBL:KLU67121.1};
OS Desulfosporosinus acididurans.
OC Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales;
OC Desulfitobacteriaceae; Desulfosporosinus.
OX NCBI_TaxID=476652 {ECO:0000313|EMBL:KLU67121.1, ECO:0000313|Proteomes:UP000036356};
RN [1] {ECO:0000313|EMBL:KLU67121.1, ECO:0000313|Proteomes:UP000036356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M1 {ECO:0000313|EMBL:KLU67121.1,
RC ECO:0000313|Proteomes:UP000036356};
RA Poehlein A., Petzsch P., Johnson B.D., Schloemann M., Daniel R.,
RA Muehling M.;
RT "Draft genome of the moderately acidophilic sulfate reducer Candidatus
RT Desulfosporosinus acididurans strain M1.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLU67121.1}.
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DR EMBL; LDZY01000003; KLU67121.1; -; Genomic_DNA.
DR RefSeq; WP_047808955.1; NZ_LDZY01000003.1.
DR AlphaFoldDB; A0A0J1IR04; -.
DR STRING; 476652.DEAC_c10600; -.
DR PATRIC; fig|476652.3.peg.1086; -.
DR Proteomes; UP000036356; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR FunFam; 2.40.30.10:FF:000020; Translation elongation factor EF-1; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:KLU67121.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000036356}.
FT DOMAIN 3..174
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 631 AA; 71081 MW; 8CF1336CA46D2062 CRC64;
MVERHYLIGT AGHVDHGKTE LIRALSGIET DRLREEKQRG ISIELGFAHM LLPSGRKVGI
VDVPGHEKFI RQMLAGASGM DIVMLVIAAD EGIMPQTKEH LDILTLLEIP RGIVVINKVD
LVDEEWLELM EEDIREKLKD TVFHDAPICR VSAVKGLGID ALKNEIDKLL SEVECKSSSG
PIRMPIDRVF SIQGFGTVVT GTLQSGTISL GQELLIEPGE IVAKVRSIQV HNQKVKDSGA
GQRVAVNLAG VEVAEVERGS VLVSPKVFQV GNILDLSLHN LPSSVKPITQ RQRVRFHLGT
TEILGRIHLL NHDELPPGQN GFAQILLEEP VLAAPGDRFV LRFYSPTQTI GGGKVLGVAD
FKKKRFKENV LDQMRIKDLG DPLELLEKEI NEPRSFEELL TCLQINAEEL DKRITTLKNN
NRVEIFMEDD TKLLWGIEEA EKWRRSLIEV VMNYEKQNPL RLGISRGELK TRLGIQWTNR
RWQTVLEQGA KYNTYYLKGS KVQTTEHAIM PPLIAKRLQE LSGRWESFKL MPPDLQAGAE
NVGISKNEAV EYAQYLCEIG EWIHIDQLYY PQKEIEGAQT VLTDFLKKQG EIAVSEVREL
LGISRKYAVP LLEYFDQQKV TKRVGDKRTL C
//
