ID A0A0K3C8N5_RHOTO Unreviewed; 719 AA.
AC A0A0K3C8N5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 18-JUN-2025, entry version 36.
DE SubName: Full=BY PROTMAP: gi|472586719|gb|EMS24238.1| regulatory subunit for Cdc7p protein kinase [Rhodosporidium toruloides NP11] gi|647398132|emb|CDR41759.1| RHTO0S06e05710g1_1 [Rhodosporidium toruloides] {ECO:0000313|EMBL:CTR06099.1};
DE SubName: Full=Dfp1/Him1, central region-domain containing protein {ECO:0000313|EMBL:PRQ76196.1};
GN Name=FGENESH: predicted gene_3.411 {ECO:0000313|EMBL:CTR06099.1};
GN ORFNames=AAT19DRAFT_13218 {ECO:0000313|EMBL:PRQ76196.1},
GN BN2166_0019600 {ECO:0000313|EMBL:CTR06099.1};
OS Rhodotorula toruloides (Yeast) (Rhodosporidium toruloides).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=5286 {ECO:0000313|EMBL:CTR06099.1, ECO:0000313|Proteomes:UP000199069};
RN [1] {ECO:0000313|EMBL:CTR06099.1, ECO:0000313|Proteomes:UP000199069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Single colony {ECO:0000313|EMBL:CTR06099.1};
RA Cajimat M.N.B., Milazzo M.L., Fulhorst C.F.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PRQ76196.1, ECO:0000313|Proteomes:UP000239560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 0880 {ECO:0000313|EMBL:PRQ76196.1,
RC ECO:0000313|Proteomes:UP000239560};
RX PubMed=29521624;
RA Coradetti S.T., Pinel D., Geiselman G., Ito M., Mondo S., Reilly M.C.,
RA Cheng Y.F., Bauer S., Grigoriev I., Gladden J.M., Simmons B.A., Brem R.,
RA Arkin A.P., Skerker J.M.;
RT "Functional genomics of lipid metabolism in the oleaginous yeast
RT Rhodosporidium toruloides.";
RL Elife 7:0-0(2018).
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DR EMBL; CWKI01000003; CTR06099.1; -; Genomic_DNA.
DR EMBL; LCTV02000003; PRQ76196.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K3C8N5; -.
DR STRING; 5286.A0A0K3C8N5; -.
DR OMA; GMKIWAI; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000199069; Unassembled WGS sequence.
DR Proteomes; UP000239560; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CTR06099.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000199069};
KW Transferase {ECO:0000313|EMBL:CTR06099.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 165..213
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 588..637
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 86..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 130..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..108
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..241
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..553
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..666
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..703
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 719 AA; 77095 MW; 0E54F11BD2202846 CRC64;
MATATTPNSH RQATQSHNSR THSVRTVSCA QLAQDSRPPA PPFVEQQLRF VQALGGGAND
VGPTSVPMQT SRIDGRTAAA AAAAAAGSRK RAAVEQDDTR SPDAADKRQA KRSRGANPLA
ALSVNVAAGG AEKGAADGTK RKSRKTYAGA EKEKLQHESQ QWRAKYRKAF PSFTFYFDAV
DDSTKASLSA AVKKLGASVD NFFSKKVTHV VTSRPLPSTS GKENAGAAAS KASTSASAST
SRSKKTSARS PKTYELPNGQ KLWPLANATD HDKNPFIDSQ DILSKALDFG LKVWASEKLQ
LIIDRINHAS PNKDKASLQR DPSLPTLLRD EQLYGTRERD PLVARADMHY FPSTKSYLLV
EDSTGEHRPI VVKEYERPKK NEVPSWPVLW GGIEGRTGFY YYDGPEITYE RRVPPRPAPA
PAATNGKAGG FGSTAARAVA PNLRRAVSLQ NVARGQQATY GYAGYEPAGR RDSYIAASGN
SQIITSNIQS ATSTAARSGT AQANRFGNPY VDKRLAVLSN RTVSVAGGSI LGSGSTAGGS
GGVASGSAGG SGGRLAALKR SERPGALKRS LSVDGHLARV PNPPVRDEPK KAGYCENCRI
KYDCFREHVR SSKHRRFALN PKNWADLDKL LQRIARKPLE AGEWERGEEG ASSELAADEG
EYEDSGYFDA SVLAGDAEEC EGDSAQDDGD EDEVMDEEEE EEESSKPLEA QVLAQAVRA
//
