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Database: UniProt
Entry: A0A0L1I5S9_PLAFA
LinkDB: A0A0L1I5S9_PLAFA
Original site: A0A0L1I5S9_PLAFA 
ID   A0A0L1I5S9_PLAFA        Unreviewed;       492 AA.
AC   A0A0L1I5S9;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   02-JUN-2021, entry version 18.
DE   RecName: Full=S-antigen protein {ECO:0000256|ARBA:ARBA00015853};
GN   ORFNames=PFMG_01038 {ECO:0000313|EMBL:KNG74832.1};
OS   Plasmodium falciparum IGH-CR14.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=580059 {ECO:0000313|EMBL:KNG74832.1, ECO:0000313|Proteomes:UP000054562};
RN   [1] {ECO:0000313|Proteomes:UP000054562}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG   The Broad Institute Genome Sequencing Platform;
RA   Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA   Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA   Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA   Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "Annotation of Plasmodium falciparum IGH-CR14.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000054562}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG   The Broad Institute Genome Sequencing Platform;
RA   Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Godfrey P., Alvarado L.,
RA   Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA   Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA   White J., Yandava C., Wirth D.F., Nusbaum C., Birren B.;
RT   "The genome sequence of Plasmodium falciparum IGH-CR14.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: S antigens are soluble heat-stable proteins present in the
CC       sera of some infected individuals. {ECO:0000256|ARBA:ARBA00003457}.
CC   -!- SUBCELLULAR LOCATION: Parasitophorous vacuole
CC       {ECO:0000256|ARBA:ARBA00004290}. Vacuole
CC       {ECO:0000256|ARBA:ARBA00004116}.
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DR   EMBL; GG665008; KNG74832.1; -; Genomic_DNA.
DR   EnsemblProtists; KNG74832; KNG74832; PFMG_01038.
DR   Proteomes; UP000054562; Unassembled WGS sequence.
DR   GO; GO:0020003; C:symbiont-containing vacuole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008825; S-antigen.
DR   Pfam; PF05756; S-antigen; 1.
PE   4: Predicted;
KW   Collagen {ECO:0000313|EMBL:KNG74832.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054562};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          1..88
FT                   /note="S-antigen"
FT                   /evidence="ECO:0000259|Pfam:PF05756"
FT   REGION          49..492
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..76
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..455
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        458..477
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   492 AA;  48176 MW;  406876091CA55A23 CRC64;
     MNRILSVSFY LFFLYLYIYK TYGKVKNTDH ELSNIYGIKY YLRNGLSDKK NGKGQKYQDL
     EEDENDDEED SNSEESNNDE ENKLIEGQGN QTEGTSGGKG DQTEGTSGGK GDQTEGTSGG
     KGDQTEGTSG GKGDQTEGTS GGKGDQTEGT SGGKGDQTEG TSGGKGDQTE GTSGGKGDQT
     EGTSGGKGDQ TEGTSGGKGD QTEGTSGGKG DQTEGSSGGK GDQTEGTSGG KGDQTEGTSG
     GKGDQTEGTS GGKGDQTEGS SGGKGDQTEG TSGGKGDQTE GTSGGKGDQT EGSSGGKGDQ
     TEGTSGGKGD QTEGTSGGKG DQTEGTSGGK GDQTEGTSGG KGDQTEGSSG GKGDQTEGTS
     GGKGDQTEGT SGGKGDQTEG SSGGKGDQTE GSSGGKGDQT EGSSGGKGDQ TEGSSGGKGD
     QTEGSSGGKG DQTEGSSGGK GDQTEGSSGG KGDQTEGSSG GDGKDGKHSH NSGNDNKNKK
     SKYSIINMLI GI
//
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