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Database: UniProt
Entry: A0A0L7LW62_PLAF4
LinkDB: A0A0L7LW62_PLAF4
Original site: A0A0L7LW62_PLAF4 
ID   A0A0L7LW62_PLAF4        Unreviewed;       331 AA.
AC   A0A0L7LW62;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   02-JUN-2021, entry version 19.
DE   RecName: Full=S-antigen protein {ECO:0000256|ARBA:ARBA00015853};
GN   ORFNames=PFDG_00158 {ECO:0000313|EMBL:KOB84824.1};
OS   Plasmodium falciparum (isolate Dd2).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=57267 {ECO:0000313|EMBL:KOB84824.1, ECO:0000313|Proteomes:UP000054282};
RN   [1] {ECO:0000313|Proteomes:UP000054282}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA   Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA   Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA   Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "Annotation of Plasmodium falciparum Dd2.";
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000054282}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Henn M., Jaffe D.,
RA   Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA   Brockman W., MacCallum I.A., Rounsley S., Young S., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Kodira C., Zeng Q., O'Leary S., Yandava C., Alvarado L., Wirth D.,
RA   Volkman S., Hartl D.;
RT   "The genome sequence of Plasmodium falciparum Dd2.";
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: S antigens are soluble heat-stable proteins present in the
CC       sera of some infected individuals. {ECO:0000256|ARBA:ARBA00003457}.
CC   -!- SUBCELLULAR LOCATION: Parasitophorous vacuole
CC       {ECO:0000256|ARBA:ARBA00004290}. Vacuole
CC       {ECO:0000256|ARBA:ARBA00004116}.
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DR   EMBL; DS016067; KOB84824.1; -; Genomic_DNA.
DR   EnsemblProtists; KOB84824; KOB84824; PFDG_00158.
DR   OMA; AGTEGPK; -.
DR   Proteomes; UP000054282; Unassembled WGS sequence.
DR   GO; GO:0020003; C:symbiont-containing vacuole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008825; S-antigen.
DR   Pfam; PF05756; S-antigen; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054282};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..331
FT                   /note="S-antigen protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005573565"
FT   DOMAIN          1..92
FT                   /note="S-antigen"
FT                   /evidence="ECO:0000259|Pfam:PF05756"
FT   REGION          47..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..90
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        96..267
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   331 AA;  38017 MW;  6BA4A0214FA0AD22 CRC64;
     MNRILSVSFY LFFLYLYIYK TYGKVKNTDQ EISNIYGTNY YLRNGFLNGK NGKGNKYEDL
     QEEGEGENDD EEHSNSEESD NDEENEIIVG QDGSDQEVKV QKEQEDQEVK VQKEQEDQEV
     KVQKEQEDQE VKVQKEQEDQ EVKVQKEQED QEVKVQKEQE DQEVKVQKEQ EDQEVKVQKE
     QEDQEVKVQK EQEDQEVKVQ KEQEDQEVKV QKEQEDQEVK VQKEQEDQEV KVQKEQEDQE
     VKVQKEQEDQ EVKVQKEQED QEVKVQKEQG PKGTGGPGSE AGTEGPKGTG GPGSEAGTEG
     PKGTGGPGSG GEHSHNKKKS KKSIMNMLIG V
//
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