ID A0A0L8LJ54_9ACTN Unreviewed; 337 AA.
AC A0A0L8LJ54;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 28-JAN-2026, entry version 41.
DE SubName: Full=RNA polymerase sigma factor {ECO:0000313|EMBL:KOG38147.1};
GN ORFNames=ADK37_10425 {ECO:0000313|EMBL:KOG38147.1};
OS Streptomyces resistomycificus.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=67356 {ECO:0000313|EMBL:KOG38147.1, ECO:0000313|Proteomes:UP000037251};
RN [1] {ECO:0000313|Proteomes:UP000037251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2290 {ECO:0000313|Proteomes:UP000037251};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOG38147.1}.
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DR EMBL; LGUS01000094; KOG38147.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8LJ54; -.
DR STRING; 67356.AQJ84_13760; -.
DR PATRIC; fig|67356.5.peg.2248; -.
DR eggNOG; COG1191; Bacteria.
DR Proteomes; UP000037251; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.20.120.1810; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR014322; RNA_pol_sigma-B/F/G.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02980; SigBFG; 1.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30385:SF4; RNA POLYMERASE SIGMA-E FACTOR; 1.
DR PANTHER; PTHR30385; SIGMA FACTOR F FLAGELLAR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037251};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 117..186
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 199..257
FT /note="RNA polymerase sigma-70 region 3"
FT /evidence="ECO:0000259|Pfam:PF04539"
FT DOMAIN 282..331
FT /note="RNA polymerase sigma-70 region 4"
FT /evidence="ECO:0000259|Pfam:PF04545"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 337 AA; 37546 MW; 290E5D595F80529C CRC64;
MADGIDGIPE QARPHPEDAS SESGFLEDGQ RDREGAVQST PLDGRIGVSP VRAQARARGR
ATGGTMSEHE RDDEKAAQRV QATRHSPQDR SGARAMFLEL RALKDGSPEY AELRNQLVRM
HLPLVEHLAR RFRNRGEPLD DLTQVATIGL IKSVDRFDPD RGVEFSTYAT PTVVGEIKRH
FRDKGWAVRV PRRLQELRLS LTTATAELSQ QHGRSPTVHE LAEKLAISEE EVLEGLESAN
AYSTLSLDVP DTDDESPAVA DTLGAEDEAL EGVEYRESLK PLLEDLPPRE KRILLLRFFG
NMTQSQIAQE VGISQMHVSR LLARTLAQLR EKLLVEE
//
