ID A0A0M2UTZ6_9BACT Unreviewed; 677 AA.
AC A0A0M2UTZ6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 28-JAN-2026, entry version 34.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=BROFUL_01760 {ECO:0000313|EMBL:KKO19533.1};
OS Candidatus Brocadia fulgida.
OC Bacteria; Pseudomonadati; Planctomycetota; Candidatus Brocadiia;
OC Candidatus Brocadiales; Candidatus Brocadiaceae; Candidatus Brocadia.
OX NCBI_TaxID=380242 {ECO:0000313|EMBL:KKO19533.1, ECO:0000313|Proteomes:UP000034954};
RN [1] {ECO:0000313|EMBL:KKO19533.1, ECO:0000313|Proteomes:UP000034954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RU1 {ECO:0000313|EMBL:KKO19533.1};
RX PubMed=24267221; DOI=10.1186/1471-2180-13-265;
RA Ferousi C., Speth D.R., Reimann J., Op den Camp H.J., Allen J.W.,
RA Keltjens J.T., Jetten M.S.;
RT "Identification of the type II cytochrome c maturation pathway in anammox
RT bacteria by comparative genomics.";
RL BMC Microbiol. 13:265-265(2013).
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKO19533.1}.
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DR EMBL; LAQJ01000182; KKO19533.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2UTZ6; -.
DR PATRIC; fig|380242.3.peg.2182; -.
DR Proteomes; UP000034954; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR FunFam; 3.40.50.300:FF:001064; Selenocysteine-specific translation elongation factor; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:KKO19533.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000034954}.
FT DOMAIN 15..186
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 677 AA; 74625 MW; 6D93234079883CB4 CRC64;
MKQASLQQPT GAHHIEHIII GTAGHIDHGK TSLVKALTGI DTDRLPEEKK RGLTIDLGFA
YLDLNENRRV SIVDVPGHER FVKNMLAGAT SINLVIFVVA ADDGIMPQTI EHLEIINLLG
IRHGIIALTK KDLVTDEWLA VVQEDIKKTV TGTSLEHAPI IPVSVVTGEG IETCETAIRE
LIARAQTQSS RRVFRMPIDR SFTIPGYGCV VTGPVLGGQI AVEDEIELLP TKKALRVRGI
EVTGERVTSA FAGQRAALNL AGVKSAEIQR GYELSVPGYL QPASAIDALL RLIKSAKTVL
KNRARIRFYL NTAEVMGRVV LLDRDALKPG EEVLCQVLLE DLITTEREDR FIIRSYSPAY
TIGGGKVLRY NTTRLKRFQE KTIKTLKILA SGNLPDIVEQ VYLNNIHVCR DERPFAPTVD
DVSRQVNIHP STAEDAIAGL VKKGLLLKFL VEGKDIVVHR DVIAAVKEQI LSTLKAFHKE
NPVKTGIEES QLRTSVATGL LPALKKVKAR AGESRPKSIS GEELHPFLFT AALSVLKNEK
AIKITDNKLS LMDFRLEVSA RDKGAADKIE EAFLKAGFTP PFAEEVVTKF GASGKAAISL
LAEQKKLIMI ENGLYFHATI LNKIKELVRD HVAKNGPMSV AQFRDLIRTT RKYAVPLLEY
LDAIHFTKRT GDVRIVL
//
